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Paul M. Thompson, PhD
Professor of Ophthalmology, Neurology, Psychiatry and The Behavioral Sciences, Radiology, Psychiatry, and Engineering
Associate Director, USC Mark and Mary Stevens Neuroimaging and Informatics Institute
USC Institute for Neuroimaging and Informatics
ISI, 4676 Admiralty Way, Ste. 200 Health Sciences Campus Marina Del Rey
+1 323 442 7246

Overview

Paul Thompson is a Professor in the Keck School of Medicine of USC. His team's research projects focus on the neuroscience, mathematics, computer science, software engineering and clinical aspects of neuroimaging and brain mapping.

Paul Thompson directs the ENIGMA Consortium, a global alliance of 307 scientists in 33 countries who conduct the largest studies of 10 major brain diseases – ranging from schizophrenia, depression, ADHD, bipolar illness and OCD, to HIV and addictions on the brain. ENIGMA’s genomic screens of over 31,000 people’s brain scans and genome-wide data (published in Nature Genetics, 2012; Nature, 2015) have brought together experts from 185 institutions to unearth genetic variants that affect brain structure, disease risk, and brain connectivity. At USC, Dr. Thompson is a Professor of Neurology, Psychiatry, Radiology, Pediatrics, Engineering, and Ophthalmology, and Director of the ENIGMA Center for Worldwide Medicine, Imaging & Genomics - a $11M NIH Center of Excellence in Big Data Computing. Using worldwide medication screens, ENIGMA discovers factors that affect progression of Alzheimer’s disease and other dementias, schizophrenia, depression and childhood brain
disorders. One study unites teams from the Thai Red Cross, the US, and South Africa, and uses methods developed by Dr Thompson’s team (Nature, 2000) to study how treatments restore brain growth in HIV+ children. Dr. Thompson also directs the USC Imaging Genetics Center– a group of 40 scientists in Marina del Rey. His team created the first maps of Alzheimer’s disease and schizophrenia spreading in the living brain, and a method to track brain growth in children. Dr. Thompson has an M.A. in mathematics and Greek and Latin Languages from Oxford University, and a PhD in neuroscience from UCLA.

Collaborating with imaging labs around the world, Dr. Thompson and his students have published over 1,300 publications (h-index: 116) describing novel mathematical and computational strategies for analyzing brain image databases, for detecting pathology in individual patients and groups, and for creating disease-specific atlases of the human brain.

Recent work has discovered new structural and functional brain changes during brain development and degeneration, Alzheimer's Disease and other dementias, schizophrenia and bipolar illness, HIV/AIDS, methamphetamine abuse, and autism. For many of these illnesses, Dr. Thompson's Center is creating population-based tools to understand factors that resist them. New computational tools, developed in the lab, are used to map how these diseases spread in the living brain, and in drug trials and basic research studies.

Awards

Kent Innovations in Academia Award

Eiduson Award for Neuroscience Research

Di Chiro Outstanding Scientific Paper Award

Outstanding Graduate Student of the Year, UCLA, UCLA Chancellor's Service Award

SPIE Medical Imaging Award, Best Paper

Publications

Continuous representations of brain connectivity using spatial point processes. Med Image Anal. 2017 Oct; 41:32-39. View in: PubMed

Volumetric grey matter alterations in adolescents and adults born very preterm suggest accelerated brain maturation. Neuroimage. 2017 Sep 20. View in: PubMed

Genetic influences on individual differences in longitudinal changes in global and subcortical brain volumes: Results of the ENIGMA plasticity working group. Hum Brain Mapp. 2017 Sep; 38(9):4444-4458. View in: PubMed

Association of White Matter With Core Cognitive Deficits in Patients With Schizophrenia. JAMA Psychiatry. 2017 Sep 01; 74(9):958-966. View in: PubMed

Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study. Alzheimers Dement. 2017 Jul 22. View in: PubMed

The attribution of animacy and agency in frontotemporal dementia versus Alzheimer's disease. Cortex. 2017 Jul; 92:81-94. View in: PubMed

Mapping 22q11. 2 Gene Dosage Effects on Brain Morphometry. J Neurosci. 2017 Jun 28; 37(26):6183-6199. View in: PubMed

White matter hyperintensities correlate to cognition and fiber tract integrity in older adults with HIV. J Neurovirol. 2017 Jun; 23(3):422-429. View in: PubMed

Association and Causation in Brain Imaging in the Case of OCD: Response to McKay et al. Am J Psychiatry. 2017 Jun 01; 174(6):597-599. View in: PubMed

Improving data availability for brain image biobanking in healthy subjects: Practice-based suggestions from an international multidisciplinary working group. Neuroimage. 2017 Jun; 153:399-409. View in: PubMed

Multi-Source Multi-Target Dictionary Learning for Prediction of Cognitive Decline. Inf Process Med Imaging. 2017 Jun; 10265:184-197. View in: PubMed

Genome-wide association study of working memory brain activation. Int J Psychophysiol. 2017 May; 115:98-111. View in: PubMed

Emerging Global Initiatives in Neurogenetics: The Enhancing Neuroimaging Genetics through Meta-analysis (ENIGMA) Consortium. Neuron. 2017 Apr 19; 94(2):232-236. View in: PubMed

The C677T variant in MTHFR modulates associations between brain integrity, mood, and cognitive functioning in old age. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Apr; 2(3):280-288. View in: PubMed

EMPOWERING CORTICAL THICKNESS MEASURES IN CLINICAL DIAGNOSIS OF ALZHEIMER'S DISEASE WITH SPHERICAL SPARSE CODING. Proc IEEE Int Symp Biomed Imaging. 2017 Apr; 2017:446-450. View in: PubMed

Fractional anisotropy derived from the diffusion tensor distribution function boosts power to detect Alzheimer's disease deficits. Magn Reson Med. 2017 Mar 07. View in: PubMed

3D tract-specific local and global analysis of white matter integrity in Alzheimer's disease. Hum Brain Mapp. 2017 Mar; 38(3):1191-1207. View in: PubMed

Brain Structure and Function Associated with Younger Adults in Growth Hormone Receptor-Deficient Humans. J Neurosci. 2017 Feb 15; 37(7):1696-1707. View in: PubMed

Predicting brain network changes in Alzheimer's disease with link prediction algorithms. Mol Biosyst. 2017 Feb 15. View in: PubMed

Relationship of a common OXTR gene variant to brain structure and default mode network function in healthy humans. Neuroimage. 2017 Feb 15; 147:500-506. View in: PubMed

Reproducibility of tract-based white matter microstructural measures using the ENIGMA-DTI protocol. Brain Behav. 2017 Feb; 7(2):e00615. View in: PubMed

Multimodal neuroimaging of male and female brain structure in health and disease across the life span. J Neurosci Res. 2017 Jan 02; 95(1-2):371-379. View in: PubMed

Distinct Subcortical Volume Alterations in Pediatric and Adult OCD: A Worldwide Meta- and Mega-Analysis. Am J Psychiatry. 2017 01 01; 174(1):60-69. View in: PubMed

Generalized reduced rank latent factor regression for high dimensional tensor fields, and neuroimaging-genetic applications. Neuroimage. 2017 Jan 01; 144(Pt A):35-57. View in: PubMed

Independent value added by diffusion MRI for prediction of cognitive function in older adults. Neuroimage Clin. 2017; 14:166-173. View in: PubMed

Diverging volumetric trajectories following pediatric traumatic brain injury. Neuroimage Clin. 2017; 15:125-135. View in: PubMed

Enhancing Diffusion MRI Measures By Integrating Grey and White Matter Morphometry With Hyperbolic Wasserstein Distance. Proc IEEE Int Symp Biomed Imaging. 2017; 2017:520-524. View in: PubMed

Heritability of the shape of subcortical brain structures in the general population. Nat Commun. 2016 Dec 15; 7:13738. View in: PubMed

Cerebral amyloid is associated with greater white-matter hyperintensity accrual in cognitively normal older adults. Neurobiol Aging. 2016 Dec; 48:48-52. View in: PubMed

An advanced white matter tract analysis in frontotemporal dementia and early-onset Alzheimer's disease. Brain Imaging Behav. 2016 Dec; 10(4):1038-1053. View in: PubMed

Heterochronicity of white matter development and aging explains regional patient control differences in schizophrenia. Hum Brain Mapp. 2016 Dec; 37(12):4673-4688. View in: PubMed

ApoE e4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60. J Acquir Immune Defic Syndr. 2016 Dec 01; 73(4):426-432. View in: PubMed

Diffusion-weighted imaging uncovers likely sources of processing-speed deficits in schizophrenia. Proc Natl Acad Sci U S A. 2016 Nov 22; 113(47):13504-13509. View in: PubMed

Relationships Between Altered Functional Magnetic Resonance Imaging Activation and Cortical Thickness in Patients With Euthymic Bipolar I Disorder. Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Nov; 1(6):507-517. View in: PubMed

Neural correlates of proactive and reactive aggression in adolescent twins. Aggress Behav. 2016 Oct 21. View in: PubMed

Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. Brain Imaging Behav. 2016 Oct 13. View in: PubMed

Hyperbolic Space Sparse Coding with Its Application on Prediction of Alzheimer's Disease in Mild Cognitive Impairment. Med Image Comput Comput Assist Interv. 2016 Oct; 9900:326-334. View in: PubMed

Effect of Electroconvulsive Therapy on Striatal Morphometry in Major Depressive Disorder. Neuropsychopharmacology. 2016 Sep; 41(10):2481-91. View in: PubMed

The C677T variant in MTHFR modulates associations between blood-based and cerebrospinal fluid biomarkers of neurodegeneration. Neuroreport. 2016 Aug 17; 27(12):948-51. View in: PubMed

Age, APOE and sex: Triad of risk of Alzheimer's disease. J Steroid Biochem Mol Biol. 2016 Jun; 160:134-47. View in: PubMed

Heritability and genetic correlation between the cerebral cortex and associated white matter connections. Hum Brain Mapp. 2016 Jun; 37(6):2331-47. View in: PubMed

Tensor-Based Morphometry Reveals Volumetric Deficits in Moderate=Severe Pediatric Traumatic Brain Injury. J Neurotrauma. 2016 May 01; 33(9):840-52. View in: PubMed

MORPHOMETRIC ANALYSIS OF HIPPOCAMPUS AND LATERAL VENTRICLE REVEALS REGIONAL DIFFERENCE BETWEEN COGNITIVELY STABLE AND DECLINING PERSONS. Proc IEEE Int Symp Biomed Imaging. 2016 Apr; 2016:14-18. View in: PubMed

APPLYING SPARSE CODING TO SURFACE MULTIVARIATE TENSOR-BASED MORPHOMETRY TO PREDICT FUTURE COGNITIVE DECLINE. Proc IEEE Int Symp Biomed Imaging. 2016 Apr; 2016:646-650. View in: PubMed

Heritability and reliability of automatically segmented human hippocampal formation subregions. Neuroimage. 2016 Mar; 128:125-37. View in: PubMed

Disrupted rich club network in behavioral variant frontotemporal dementia and early-onset Alzheimer's disease. Hum Brain Mapp. 2016 Mar; 37(3):868-83. View in: PubMed

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nat Neurosci. 2016 Mar; 19(3):420-431. View in: PubMed

Heritability of complex white matter diffusion traits assessed in a population isolate. Hum Brain Mapp. 2016 Feb; 37(2):525-35. View in: PubMed

The common genetic influence over processing speed and white matter microstructure: Evidence from the Old Order Amish and Human Connectome Projects. Neuroimage. 2016 Jan 15; 125:189-197. View in: PubMed

Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. PLoS One. 2016; 11(3):e0152082. View in: PubMed

Influence of APOE Genotype on Hippocampal Atrophy over Time - An N=1925 Surface-Based ADNI Study. PLoS One. 2016; 11(4):e0152901. View in: PubMed

Genes influence the amplitude and timing of brain hemodynamic responses. Neuroimage. 2016 Jan 01; 124(Pt A):663-71. View in: PubMed

Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. PLoS One. 2016; 11(9):e0163669. View in: PubMed

Head Motion and Inattention/Hyperactivity Share Common Genetic Influences: Implications for fMRI Studies of ADHD. PLoS One. 2016; 11(1):e0146271. View in: PubMed

Genetic imaging consortium for addiction medicine: From neuroimaging to genes. Prog Brain Res. 2016; 224:203-23. View in: PubMed

MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trials. Neurobiol Aging. 2016 Jan; 37:26-37. View in: PubMed

Quantitative magnetic resonance imaging traits as endophenotypes for genetic mapping in epilepsy. Neuroimage Clin. 2016; 12:526-534. View in: PubMed

Cracking the brain's genetic code. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):15269-70. View in: PubMed

Heritability of the network architecture of intrinsic brain functional connectivity. Neuroimage. 2015 Nov 01; 121:243-52. View in: PubMed

Carriers of a common variant in the dopamine transporter gene have greater dementia risk, cognitive decline, and faster ventricular expansion. Alzheimers Dement. 2015 Oct; 11(10):1153-62. View in: PubMed

Brain Imaging and Neurodevelopment in HIV-uninfected Thai Children Born to HIV-infected Mothers. Pediatr Infect Dis J. 2015 Sep; 34(9):e211-6. View in: PubMed

Structural Brain Changes in Early-Onset Alzheimer's Disease Subjects Using the LONI Pipeline Environment. J Neuroimaging. 2015 Sep-Oct; 25(5):728-37. View in: PubMed

Genomic structural variants are linked with intellectual disability. J Neural Transm (Vienna). 2015 Sep; 122(9):1289-301. View in: PubMed

Rich club analysis in the Alzheimer's disease connectome reveals a relatively undisturbed structural core network. Hum Brain Mapp. 2015 Aug; 36(8):3087-103. View in: PubMed

Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans. Alzheimers Dement. 2015 Jul; 11(7):792-814. View in: PubMed

Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2. Alzheimers Dement. 2015 Jul; 11(7):740-56. View in: PubMed

Novel Neuroimaging Methods to Understand How HIV Affects the Brain. Curr HIV/AIDS Rep. 2015 Jun; 12(2):289-98. View in: PubMed

Altered regional brain volumes in elderly carriers of a risk variant for drug abuse in the dopamine D2 receptor gene (DRD2). Brain Imaging Behav. 2015 Jun; 9(2):213-22. View in: PubMed

Accelerated vs. unaccelerated serial MRI based TBM-SyN measurements for clinical trials in Alzheimer's disease. Neuroimage. 2015 Jun; 113:61-9. View in: PubMed

Plasma BDNF levels associate with Pittsburgh compound B binding in the brain. Alzheimers Dement (Amst). 2015 Jun 01; 1(2):187-193. View in: PubMed

Abnormal hippocampal morphology in dissociative identity disorder and post-traumatic stress disorder correlates with childhood trauma and dissociative symptoms. Hum Brain Mapp. 2015 May; 36(5):1692-704. View in: PubMed

Common genetic variants influence human subcortical brain structures. Nature. 2015 Apr 09; 520(7546):224-9. View in: PubMed

Information-Theoretic Characterization of Blood Panel Predictors for Brain Atrophy and Cognitive Decline in the Elderly. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:980-984. View in: PubMed

SPECTRAL GRAPH THEORY AND GRAPH ENERGY METRICS SHOW EVIDENCE FOR THE ALZHEIMER'S DISEASE DISCONNECTION SYNDROME IN APOE-4 RISK GENE CARRIERS. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:458-461. View in: PubMed

MAPPING ABNORMAL SUBCORTICAL BRAIN MORPHOMETRY IN AN ELDERLY HIV+ COHORT. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:971-975. View in: PubMed

Medial Demons Registration Localizes The Degree of Genetic Influence Over Subcortical Shape Variability: An N= 1480 Meta-Analysis. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:1402-1406. View in: PubMed

Detecting Genetic Risk Factors for Alzheimer's Disease in Whole Genome Sequence Data via Lasso Screening. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:985-989. View in: PubMed

AUTOMATED MULTI-ATLAS LABELING OF THE FORNIX AND ITS INTEGRITY IN ALZHEIMER'S DISEASE. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:140-143. View in: PubMed

FEATURE SELECTION IMPROVES THE ACCURACY OF CLASSIFYING ALZHEIMER DISEASE USING DIFFUSION TENSOR IMAGES. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:126-130. View in: PubMed

GENETIC ANALYSIS OF STRUCTURAL BRAIN CONNECTIVITY USING DICCCOL MODELS OF DIFFUSION MRI IN 522 TWINS. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:1167-1171. View in: PubMed

WHITE MATTER INTEGRITY IN TRAUMATIC BRAIN INJURY: EFFECTS OF PERMISSIBLE FIBER TURNING ANGLE. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:930-933. View in: PubMed

Random Forest Classification of Depression Status Based On Subcortical Brain Morphometry Following Electroconvulsive Therapy. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:92-96. View in: PubMed

Frontal and striatal alterations associated with psychopathic traits in adolescents. Psychiatry Res. 2015 Mar 30; 231(3):333-40. View in: PubMed

Communication of brain network core connections altered in behavioral variant frontotemporal dementia but possibly preserved in early-onset Alzheimer's disease. Proc SPIE Int Soc Opt Eng. 2015 Mar 20; 9413. View in: PubMed

7T Multi-shell Hybrid Diffusion Imaging (HYDI) for Mapping Brain Connectivity in Mice. Proc SPIE Int Soc Opt Eng. 2015 Mar 20; 9413. View in: PubMed

Subcortical shape and volume abnormalities in an elderly HIV+ cohort. Proc SPIE Int Soc Opt Eng. 2015 Mar 17; 9417. View in: PubMed

Brain amyloidosis ascertainment from cognitive, imaging, and peripheral blood protein measures. Neurology. 2015 Feb 17; 84(7):729-37. View in: PubMed

Effects of changing from non-accelerated to accelerated MRI for follow-up in brain atrophy measurement. Neuroimage. 2015 Feb 15; 107:46-53. View in: PubMed

Partial volume correction in quantitative amyloid imaging. Neuroimage. 2015 Feb 15; 107:55-64. View in: PubMed

Occipital sources of resting-state alpha rhythms are related to local gray matter density in subjects with amnesic mild cognitive impairment and Alzheimer's disease. Neurobiol Aging. 2015 Feb; 36(2):556-70. View in: PubMed

Higher homocysteine associated with thinner cortical gray matter in 803 participants from the Alzheimer's Disease Neuroimaging Initiative. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S203-10. View in: PubMed

Empowering imaging biomarkers of Alzheimer's disease. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S69-80. View in: PubMed

Does MRI scan acceleration affect power to track brain change? Neurobiol Aging. Does MRI scan acceleration affect power to track brain change? Neurobiol Aging. 2015 Jan; 36 Suppl 1:S167-77. View in: PubMed

Low plasma ApoE levels are associated with smaller hippocampal size in the Alzheimer's disease neuroimaging initiative cohort. Dement Geriatr Cogn Disord. 2015; 39(3-4):154-66. View in: PubMed

Thicker temporal cortex associates with a developmental trajectory for psychopathic traits in adolescents. PLoS One. 2015; 10(5):e0127025. View in: PubMed

Subregional Hippocampal Morphology and Psychiatric Outcome in Adolescents Who Were Born Very Preterm and at Term. PLoS One. 2015; 10(6):e0130094. View in: PubMed

Structural Neuroimaging Genetics Interactions in Alzheimer's Disease. J Alzheimers Dis. 2015; 48(4):1051-63. View in: PubMed

Mapping abnormal subcortical brain morphometry in an elderly HIV+ cohort. Neuroimage Clin. 2015; 9:564-73. View in: PubMed

Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly. Front Aging Neurosci. 2015; 7:221. View in: PubMed

Mapping ventricular expansion onto cortical gray matter in older adults. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S32-41. View in: PubMed

Boosting brain connectome classification accuracy in Alzheimer's disease using higher-order singular value decomposition. Front Neurosci. 2015; 9:257. View in: PubMed

Comparison of nine tractography algorithms for detecting abnormal structural brain networks in Alzheimer's disease. Front Aging Neurosci. 2015; 7:48. View in: PubMed

Larger hippocampal dimensions in meditation practitioners: differential effects in women and men. Front Psychol. 2015; 6:186. View in: PubMed

Studying ventricular abnormalities in mild cognitive impairment with hyperbolic Ricci flow and tensor-based morphometry. Neuroimage. 2015 Jan 01; 104:1-20. View in: PubMed

Connectivity network measures predict volumetric atrophy in mild cognitive impairment. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S113-20. View in: PubMed

Diffusion weighted imaging-based maximum density path analysis and classification of Alzheimer's disease. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S132-40. View in: PubMed

Genome-wide interaction analysis reveals replicated epistatic effects on brain structure. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S151-8. View in: PubMed

Seemingly unrelated regression empowers detection of network failure in dementia. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S103-12. View in: PubMed

White matter disruption in moderate/severe pediatric traumatic brain injury: advanced tract-based analyses. Neuroimage Clin. 2015; 7:493-505. View in: PubMed

Gene interactions and structural brain change in early-onset Alzheimer's disease subjects using the pipeline environment. Psychiatry Investig. 2015 Jan; 12(1):125-35. View in: PubMed

Brain connectivity and novel network measures for Alzheimer's disease classification. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S121-31. View in: PubMed

Connectopathy in ageing and dementia. Brain. 2014 Dec; 137(Pt 12):3104-6. View in: PubMed

Bi-level multi-source learning for heterogeneous block-wise missing data. Neuroimage. 2014 Nov 15; 102 Pt 1:192-206. View in: PubMed

Obesity gene NEGR1 associated with white matter integrity in healthy young adults. Neuroimage. 2014 Nov 15; 102 Pt 2:548-57. View in: PubMed

Heritability of head motion during resting state functional MRI in 462 healthy twins. Neuroimage. 2014 Nov 15; 102 Pt 2:424-34. View in: PubMed

Skull-stripping with machine learning deformable organisms. J Neurosci Methods. 2014 Oct 30; 236:114-24. View in: PubMed

Automatic clustering of white matter fibers in brain diffusion MRI with an application to genetics. Neuroimage. 2014 Oct 15; 100:75-90. View in: PubMed

Investigating brain connectivity heritability in a twin study using diffusion imaging data. Neuroimage. 2014 Oct 15; 100:628-41. View in: PubMed

Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease. BMC Genomics. 2014 Oct 03; 15:850. View in: PubMed

Functional connectivity in autosomal dominant and late-onset Alzheimer disease. JAMA Neurol. 2014 Sep; 71(9):1111-22. View in: PubMed

Medial temporal atrophy in early and late-onset Alzheimer's disease. Neurobiol Aging. 2014 Sep; 35(9):2004-12. View in: PubMed

Automatic clustering and population analysis of white matter tracts using maximum density paths. Neuroimage. 2014 Aug 15; 97:284-95. View in: PubMed

Genetic influence of apolipoprotein E4 genotype on hippocampal morphometry: An N = 725 surface-based Alzheimer's disease neuroimaging initiative study. Hum Brain Mapp. 2014 Aug; 35(8):3903-18. View in: PubMed

Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling. Neuroimage. 2014 Jul 15; 95:136-50. View in: PubMed

Improved DTI registration allows voxel-based analysis that outperforms tract-based spatial statistics. Neuroimage. 2014 Jul 01; 94:65-78. View in: PubMed

Fast and accurate modelling of longitudinal and repeated measures neuroimaging data. Neuroimage. 2014 Jul 01; 94:287-302. View in: PubMed

Impact of family structure and common environment on heritability estimation for neuroimaging genetics studies using Sequential Oligogenic Linkage Analysis Routines. J Med Imaging (Bellingham). 2014 Jun 27; 1(1):014005. View in: PubMed

The Australian, US, Scandinavian Imaging Exchange (AUSSIE): an innovative, virtually-integrated health research network embedded in health care. Australas Psychiatry. 2014 Jun; 22(3):260-265. View in: PubMed

Apolipoprotein E epsilon 4 allele is associated with ventricular expansion rate and surface morphology in dementia and normal aging. Neurobiol Aging. 2014 Jun; 35(6):1309-17. View in: PubMed

Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers. Brain Imaging Behav. 2014 Jun; 8(2):183-207. View in: PubMed

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav. 2014 Jun; 8(2):153-82. View in: PubMed

Cognitive and behavioral correlates of caudate subregion shape variation in fragile X syndrome. Hum Brain Mapp. 2014 Jun; 35(6):2861-8. View in: PubMed

Combined effects of Alzheimer risk variants in the CLU and ApoE genes on ventricular expansion patterns in the elderly. J Neurosci. 2014 May 07; 34(19):6537-45. View in: PubMed

OPTIMIZING BRAIN CONNECTIVITY NETWORKS FOR DISEASE CLASSIFICATION USING EPIC. Proc IEEE Int Symp Biomed Imaging. 2014 May; 2014:834-837. View in: PubMed

Age effects on cortical thickness in cognitively normal elderly individuals. Dement Geriatr Cogn Dis Extra. 2014 May; 4(2):221-7. View in: PubMed

A commonly carried genetic variant in the delta opioid receptor gene, OPRD1, is associated with smaller regional brain volumes: replication in elderly and young populations. Hum Brain Mapp. 2014 Apr; 35(4):1226-36. View in: PubMed

Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees. JAMA Psychiatry. 2014 Apr; 71(4):375-87. View in: PubMed

The subcortical connectome: hubs, spokes and the space between - a vision for further research in neurodegenerative disease. Aust N Z J Psychiatry. 2014 Apr; 48(4):306-9. View in: PubMed

Development of insula connectivity between ages 12 and 30 revealed by high angular resolution diffusion imaging. Hum Brain Mapp. 2014 Apr; 35(4):1790-800. View in: PubMed

A focus on structural brain imaging in the Alzheimer's disease neuroimaging initiative. Biol Psychiatry. 2014 Apr 01; 75(7):527-33. View in: PubMed

Regionally specific increased volume of the amygdala in Williams syndrome: evidence from surface-based modeling. Hum Brain Mapp. 2014 Mar; 35(3):866-74. View in: PubMed

Functional brain connectivity using fMRI in aging and Alzheimer's disease. Neuropsychol Rev. 2014 Mar; 24(1):49-62. View in: PubMed

Mapping white matter integrity in elderly people with HIV. Hum Brain Mapp. 2014 Mar; 35(3):975-92. View in: PubMed

Analysis of sampling techniques for imbalanced data: An n = 648 ADNI study. Neuroimage. 2014 Feb 15; 87:220-41. View in: PubMed

Segmentation of high angular resolution diffusion MRI using sparse riemannian manifold clustering. IEEE Trans Med Imaging. 2014 Feb; 33(2):301-17. View in: PubMed

Reprint of: Mapping connectivity in the developing brain. Int J Dev Neurosci. 2014 Feb; 32:41-57. View in: PubMed

Modeling of the hemodynamic responses in block design fMRI studies. J Cereb Blood Flow Metab. 2014 Feb; 34(2):316-24. View in: PubMed

Genetic effects on the cerebellar role in working memory: same brain, different genes? Neuroimage. Genetic effects on the cerebellar role in working memory: same brain, different genes? Neuroimage. 2014 Feb 01; 86:392-403. View in: PubMed

Shape analysis of the corpus callosum in Alzheimer's disease and frontotemporal lobar degeneration subtypes. J Alzheimers Dis. 2014; 40(4):897-906. View in: PubMed

Irritable bowel syndrome in female patients is associated with alterations in structural brain networks. Pain. 2014 Jan; 155(1):137-49. View in: PubMed

Algebraic connectivity of brain networks shows patterns of segregation leading to reduced network robustness in Alzheimer's disease. Comput Diffus MRI (2014). 2014; 2014:55-64. View in: PubMed

Why size matters: differences in brain volume account for apparent sex differences in callosal anatomy: the sexual dimorphism of the corpus callosum. Neuroimage. 2014 Jan 01; 84:820-4. View in: PubMed

Brain putamen volume changes in newly-diagnosed patients with obstructive sleep apnea. Neuroimage Clin. 2014; 4:383-91. View in: PubMed

Altered white matter microstructure is associated with social cognition and psychotic symptoms in 22q11. 2 microdeletion syndrome. Front Behav Neurosci. 2014; 8:393. View in: PubMed

Relation of callosal structure to cognitive abilities in temporal lobe epilepsy. Front Neurol. 2014; 5:16. View in: PubMed

Effects of sex chromosome dosage on corpus callosum morphology in supernumerary sex chromosome aneuploidies. Biol Sex Differ. 2014; 5:16. View in: PubMed

ApoE4 effects on automated diagnostic classifiers for mild cognitive impairment and Alzheimer's disease. Neuroimage Clin. 2014; 4:461-72. View in: PubMed

Regional differences in white matter breakdown between frontotemporal dementia and early-onset Alzheimer's disease. J Alzheimers Dis. 2014; 39(2):261-9. View in: PubMed

Rich club network analysis shows distinct patterns of disruption in frontotemporal dementia and Alzheimer's disease. Math Vis. 2014; 2014:13-22. View in: PubMed

Mismatch negativity in recent-onset and chronic schizophrenia: a current source density analysis. PLoS One. 2014; 9(6):e100221. View in: PubMed

IMAGING GENETICS VIA SPARSE CANONICAL CORRELATION ANALYSIS. Proc IEEE Int Symp Biomed Imaging. 2013 Dec 31; 2013:740-743. View in: PubMed

Global and regional alterations of hippocampal anatomy in long-term meditation practitioners. Hum Brain Mapp. 2013 Dec; 34(12):3369-75. View in: PubMed

Memory performance and fMRI signal in presymptomatic familial Alzheimer's disease. Hum Brain Mapp. 2013 Dec; 34(12):3308-19. View in: PubMed

Neuroimaging, nutrition, and iron-related genes. Cell Mol Life Sci. 2013 Dec; 70(23):4449-61. View in: PubMed

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4502-9. View in: PubMed

Relation between variants in the neurotrophin receptor gene, NTRK3, and white matter integrity in healthy young adults. Neuroimage. 2013 Nov 15; 82:146-53. View in: PubMed

Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: a pilot project of the ENIGMA-DTI working group. Neuroimage. 2013 Nov 01; 81:455-69. View in: PubMed

Mapping connectivity in the developing brain. Int J Dev Neurosci. 2013 Nov; 31(7):525-42. View in: PubMed

White matter microstructural abnormalities in girls with chromosome 22q11. 2 deletion syndrome, Fragile X or Turner syndrome as evidenced by diffusion tensor imaging. Neuroimage. 2013 Nov 01; 81:441-54. View in: PubMed

TREM2 and neurodegenerative disease. N Engl J Med. 2013 Oct 17; 369(16):1565-7. View in: PubMed

Genetics of the connectome. Neuroimage. 2013 Oct 15; 80:475-88. View in: PubMed

The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 2013 Oct 15; 81(16):1425-33. View in: PubMed

No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes. J Affect Disord. 2013 Oct; 151(1):291-7. View in: PubMed

Angular versus spatial resolution trade-offs for diffusion imaging under time constraints. Hum Brain Mapp. 2013 Oct; 34(10):2688-706. View in: PubMed

Understanding cognitive deficits in Alzheimer's disease based on neuroimaging findings. Trends Cogn Sci. 2013 Oct; 17(10):510-6. View in: PubMed

The right inhibition? Callosal correlates of hand performance in healthy children and adolescents callosal correlates of hand performance. Hum Brain Mapp. 2013 Sep; 34(9):2259-65. View in: PubMed

Surface fluid registration of conformal representation: application to detect disease burden and genetic influence on hippocampus. Neuroimage. 2013 Sep; 78:111-34. View in: PubMed

Typical and atypical brain development: a review of neuroimaging studies. Dialogues Clin Neurosci. 2013 Sep; 15(3):359-84. View in: PubMed

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Time-lapse mapping of cortical changes in schizophrenia with different treatments. Cereb Cortex. 2009 May; 19(5):1107-23. View in: PubMed

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Extending genetic linkage analysis to diffusion tensor images to map single gene effects on brain fiber architecture. Med Image Comput Comput Assist Interv. 2009; 12(Pt 2):506-13. View in: PubMed

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Three-dimensional mapping of the lateral ventricles in autism. Psychiatry Res. 2008 Jul 15; 163(2):106-15. View in: PubMed

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Abnormal cortical thickness and brain-behavior correlation patterns in individuals with heavy prenatal alcohol exposure. Cereb Cortex. 2008 Jan; 18(1):136-44. View in: PubMed

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