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Senta K. Georgia, PhD

Associate Professor of Pediatrics and Stem Cell Biology & Regenerative Medicine

Admissions Chair for the Programs in Biomedical & Biological Sciences

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Phone +1 323 361 6003
Email [email protected]
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Overview

Georgia Lab Website

Georgia attended Stanford University, earning her BS in Biological Sciences, and dual departmental honors in Biological Sciences and Ethics in Society. She earned her PhD at UCLA in Molecular Biology. Her dissertation focused on the role of cell cycle molecules in the establishment, expansion and maintenance of beta cell mass. She was a postdoctoral fellow and assistant adjunct professor at the Hillblom Islet Research Center at UCLA.

Publications

  • Secretory stimuli distinctly regulate insulin secretory granule maturation through structural remodeling. Structure. 2025 Nov 06; 33(11):1831-1843.e4.. View in PubMed
  • Spike in Diabetic Ketoacidosis Rates in Pediatric Type 2 Diabetes During the COVID-19 Pandemic. Diabetes Care. 2021 06; 44(6):1451-1453.. View in PubMed
  • Gene Editing and Human Pluripotent Stem Cells: Tools for Advancing Diabetes Disease Modeling and Beta-Cell Development. Curr Diab Rep. 2017 Oct 05; 17(11):116.. View in PubMed
  • Neuropeptide Y expression marks partially differentiated β cells in mice and humans. JCI Insight. 2017 Jun 15; 2(12).. View in PubMed
  • Fibroblast growth factor 10 alters the balance between goblet and Paneth cells in the adult mouse small intestine. Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15; 308(8):G678-90.. View in PubMed
  • Congenital proprotein convertase 1/3 deficiency causes malabsorptive diarrhea and other endocrinopathies in a pediatric cohort. Gastroenterology. 2013 Jul; 145(1):138-148.. View in PubMed
  • DNMT1 represses p53 to maintain progenitor cell survival during pancreatic organogenesis. Genes Dev. 2013 Feb 15; 27(4):372-7.. View in PubMed
  • Skp2 is required for incretin hormone-mediated β-cell proliferation. Mol Endocrinol. 2011 Dec; 25(12):2134-43.. View in PubMed
  • Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx. Dev Cell. 2011 Apr 19; 20(4):419-29.. View in PubMed
  • Differential effects of prenatal and postnatal nutritional environment on ß-cell mass development and turnover in male and female rats. Endocrinology. 2010 Dec; 151(12):5647-56.. View in PubMed

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