Division of Neurocritical Care and Stroke

Research

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Featured Publication

Exploring the feasibility of EEG for pre-hospital detection of medium and large vessel occlusion strokes: a proof-of-concept study

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Explore Published Research

Our researchers harness ingenuity and dedication to drive transformative advancements in healthcare.

The link between insurance and blood pressure control in U.S. stroke survivors
Health Equity and Actionable Disparities
The National Institutes of Health Stroke Scale is comparable to the ICH score in predicting outcomes in spontaneous acute intracerebral hemorrhage
Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery
The National Institutes of Health Stroke Scale is comparable to the ICH score in predicting outcomes in spontaneous acute intracerebral hemorrhage
Trial of Thrombectomy for Stroke with a Large Infarct of Unrestricted Size
Persistent Inequities in Intravenous Thrombolysis for Acute Ischemic Stroke in the United States: Results from the Nationwide Inpatient Sample
Circadian variation in stroke onset: Differences between ischemic and hemorrhagic stroke and weekdays versus weekends
Before, during, and after: An Argument for Safety and Improved Outcome of Thrombolysis in Acute Ischemic Stroke with Direct Oral Anticoagulant Treatment

DEFUSE 3

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging
CT perfusion core and ASPECT score prediction of outcomes in DEFUSE 3
Results From DEFUSE 3: Good Collaterals Are Associated With Reduced Ischemic Core Growth but Not Neurologic Outcome

About Our Research

The Comprehensive Cerebrovascular and Stroke Center of USC is a leader in research, attracting students, residents and fellows to participate in groundbreaking clinical trials and research projects. Our research includes prehospital stroke studies, acute stroke research, as well as stroke prevention and recovery after stroke.

Oceanic-Stroke

A phase 3 study to investigate the efficacy and safety of the oral FXIa inhibitor asundexian (BAY 2433334) compared with placebo for the prevention of ischemic stroke in male and female participants aged 18 years and older after an acute non-cardioembolic ischemic stroke or high-risk TIA.

Oceanic-Stroke MRI

The focus of this sub-study is to correlate baseline MRI findings with future events (e.g. covert brain infarction, recurrent strokes, intracranial bleeding), identify asundexian responders, further characterize the study population by MRI and add additional safety information on the asundexian 50 mg dose (to the Phase 2 study).

Saturn

Study objective is to determine the effects of continuation vs. discontinuation of statins on the risk of ICH recurrence during 24 months of follow-up in patients presenting with a spontaneous lobar lCH while taking a statin drug. It also seeks to determine the effects of discontinuation vs. continuation of statins on the occurrence of major adverse cardiac and cerebrovascular events.

Saturn-MRI

Saturn-MRI is an ancillary study to SATURN, to evaluate the effects of continuation vs. discontinuation of statin drugs on hemorrhagic and    ischemic MRI markers of cerebral small vessel disease, and whether the presence/burden of hemorrhagic markers on baseline MRI influences the risk of ICH recurrence on/off statin therapy.

Protect

The purpose of this study is to determine the efficacy of an investigational stroke sensor. The study device is manufactured by StrokeDx, Inc., a medical device company based in Pasadena, CA.