Project 1: Integration of Omic Data to Estimate Mediation or Latent Structures

Overview

This project will develop statistical approaches leveraging latent structures or mediating relationships for the integration of multiple omics data to better understand gene-to-phenotype relationships. The methods will be applicable to either individual-level data or summary statistics, and they will have a direct impact on applied investigations by facilitating a better understanding of potential mechanisms driving underlying cancer etiology.