Alexander E. Weber, MD

Associate Professor of Clinical Orthopaedic Surgery

Chief, USC Epstein Family Center for Sports Medicine

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Overview

Alexander Weber, M.D. is an associate professor in the Department of Orthopaedic Surgery at the Keck School of Medicine of USC. Dr. Weber serves as chief of the USC Epstein Family Center for Sports Medicine. His focus is on the management of patients with sports medicine injuries and general orthopaedic surgery. He has a special interest in hip arthroscopy and the treatment of labral pathology around the hip joint. He also treats injuries of the knee and shoulder including: anterior cruciate ligament and meniscal injuries of the knee, and rotator cuff tears and degenerative arthritis of the shoulder joint.

Dr. Weber attended the University of Buffalo School of Medicine in Buffalo, New York. He served as a resident physician at the University of Michigan Department of Orthopaedic Surgery. He subsequently did his fellowship in sports medicine at the prestigious Rush Medical Center in Chicago, Illinois. Dr. Weber has been the Assistant Team Physician for the University of Michigan men’s basketball team, the Chicago White Sox and the Chicago Bulls. At the present time, he participates in the care of USC intercollegiate athletes.

Dr. Weber is actively engaged in scientific research and to date he has published 20 peer reviewed articles. He has presented his research work at a variety of national and international meetings. His areas of research interest include treatment of disorders of the hip, shoulder and knee.

Dr. Weber is a member of a number of national organizations including: the American Academy of Orthopaedic Surgeons, the Arthroscopy Association of North America, and the American Orthopaedic Society for Sports Medicine.

Awards

  • Los Angeles Magazine: Southern California Rising Star, 2018
     – 2022
  • Pasadena Magazine: Top Doctor, 2017
     – 2021
  • Expertscape: Expertscape World Expert in Hip Joints, 2021

Publications

  • Same reimbursement, different cost: risk factors for high-cost total shoulder arthroplasty. J Shoulder Elbow Surg. 2025 Dec; 34(12):2760-2768.. View in PubMed
  • Interscalene nerve block with plain bupivacaine versus liposomal bupivacaine for arthroscopic rotator cuff repair: A randomized controlled trial. Saudi J Anaesth. 2025 Apr-Jun; 19(2):243-250.. View in PubMed
  • Orthopedic Patients Are Highly Amenable to Cannabis-Based Products for the Treatment of Musculoskeletal Pain. Orthopedics. 2025 Mar-Apr; 48(2):98-103.. View in PubMed
  • Perioperative opioid use in total shoulder arthroplasty is associated with dose-dependent risk of major surgical and medical complications. J Shoulder Elbow Surg. 2025 Jul; 34(7):1628-1640.. View in PubMed
  • Tranexamic acid use in total shoulder arthroplasty continues to increase and is safe in high-risk patients. J Shoulder Elbow Surg. 2025 May; 34(5):1138-1151.. View in PubMed
  • The Relationship Between Surgeon Volume and Major Surgical Complications After Total Shoulder Arthroplasty: An Evaluation of 3177 US Orthopedic Surgeons. Orthopedics. 2025 Jan-Feb; 48(1):e15-e21.. View in PubMed
  • Preoperative Mental Health Disorders Affect Opioid Consumption and Perioperative Complications After Total Shoulder Arthroplasty. Orthopedics. 2024 Nov-Dec; 47(6):e303-e310.. View in PubMed
  • Effect of body mass index on complications following total shoulder arthroplasty: a population-wide analysis. J Shoulder Elbow Surg. 2025 Jan; 34(1):33-42.. View in PubMed
  • Subjective Causes for Failure to Return to Sport After Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis. Sports Health. 2025 Mar; 17(2):243-251.. View in PubMed
  • NCAA football players are at higher risk of upper extremity injury after first-time concussion. Phys Sportsmed. 2024 12; 52(6):556-560.. View in PubMed