Cheng Ji, PhD

Professor of Research Medicine

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Overview

Dr. Ji joined the faculty of Keck School of Medicine of USC in September 2000. Prior to the faculty, he earned his M.S. in Chemistry from Shanghai Jiao Tong Univ. and completed his PhD in Biochemistry and postdoctoral fellowships in Pathology/Medicine at Univ. of California and Keck School of Medicine of USC, respectively. Dr. Ji’s research interests include cellular organelle (e.g., ER, Golgi, mitochondria, or lysosomes) stress and liver disease, alcohol-induced hyperhomocysteinemia, and hepatotoxicity of anti-viral drugs and substance use disorders. He was among the first discovered in vivo the association of ER stress response with development of liver disease. Dr. Ji has published original research papers in leading journals such as Gastroenterology, Journal of Hepatology, Hepatology, PNAS, Cell, Nature Nanotech. and Advanced Materials.

Publications

  • Use of monoclonal antibodies to identify cytochrome P450 isozymes in rat liver microsomes that hydroxylate N-nitrosomethylamylamine at each of six positions. IARC Sci Publ. 1991.. View in PubMed
  • Oxidation of polycyclic hydrocarbons by oxygen radicals. Princess Takamatsu Symp. 1990; 21:63-73.. View in PubMed
  • Formation of hydroxy derivatives, aldehydes, and nitrite from N-nitrosomethyl-n-amylamine by rat liver microsomes and by purified cytochrome P-450 IIB1. Cancer Res. 1989 Oct 01; 49(19):5299-304.. View in PubMed
  • [Determination of chlorogenic acid in various processed samples of Lonicera japonica Thunb]. Zhong Yao Tong Bao. 1987 Nov; 12(11):18-9.. View in PubMed
  • Delayed internal fixation of femoral shaft fractures–is there an advantage? A review of 320 fractures. J Bone Joint Surg Br. 1987 May; 69(3):391-4.. View in PubMed
  • Metabolism of the oesophageal carcinogen N-nitrosomethylamylamine: changes with age, clearance from blood and DNA alkylation. IARC Sci Publ. 1987.. View in PubMed
  • [Induction of papilloma and carcinoma in the forestomach of mice by in vivo formation of N-3-methylbutyl-N-1-methylacetonylnitrosamine (MAMBNA)]. Zhonghua Zhong Liu Za Zhi. 1986 Jul; 8(4):245-6.. View in PubMed
  • Synthesis of nitrosomethylisoamylamine from isoamylamine and sodium nitrite by fungi. Carcinogenesis. 1986 Feb; 7(2):301-3.. View in PubMed
  • Occurrence of nitroso compounds in fungi-contaminated foods: a review. Nutr Cancer. 1986; 8(1):63-9.. View in PubMed
  • [N-nitrosoproline ethylester in moldy millet]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1985 Apr; 7(2):130-2.. View in PubMed