Christopher Haiman, ScD

Professor of Population and Public Health Sciences

AFLAC Chair in Cancer Research

Director, Center for Genetic Epidemiology

Division Chief, Epidemiology and Genetics

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Overview

Christopher Haiman, ScD, is a professor of preventive medicine at the Keck School of Medicine of USC and AFLAC Chair in Cancer Research. He also leads the Cancer Epidemiology Program at USC Norris Comprehensive Cancer Center and the Epidemiology and Genetics division in the Department of Preventive Medicine. Dr. Haiman is a genetic epidemiologist whose research is focused on exploring racial and ethnic disparities in cancer risk, with the goal of developing approaches to reduce these disparities. He is co-principal investigator of the Multiethnic Cohort (MEC), a large prospective study of cancer in primarily non-European ancestry populations (n>215,000) that has been the foundation of his scientific investigation into the genetic risk of cancer, initially through genome-wide association studies (GWAS) and more recently in large-scale genomic consortia in minority populations that employ next-generation sequencing technology. In addition to these leadership and administrative research positions, he has vast experience in directing large consortia and is currently the scientific leader of the African Ancestry Prostate Cancer Consortium (AAPC). He has also served as a steering committee member for numerous NIH consortia, including the NCI GAME-ON Consortium, NHGRI Population Architecture Using Genomics and Epidemiology Consortium (PAGE), NHGRI Gene Environment Association Studies (GENEVA) Consortium and the NCI Breast and Prostate Cancer Cohort Consortium (BPC3). He is also the principal investigator of the RESPOND African-American prostate cancer initiative. He has co-authored more than 450 peer-reviewed publications, with many in prominent journals, including Nature Genetics, The New England Journal of Medicine and Journal of the National Cancer Institute.

Research Funding

  • Post-Doctoral Training in Integrative Cancer Epidemiology
    NIH · T32CA315091 · Sep 1, 2026 – Aug 31, 2031 · Role: Principal Investigator
  • Family RESPOND: Defining the Genetic Basis of Prostate Cancer Risk in African American Families
    NIH · R01CA289492 · Apr 1, 2025 – Mar 31, 2030 · Role: Principal Investigator
  • Identifying factors associated with prostate cancer progression and survival in African American men: The RESPOND Cohort
    NIH · U01CA287036 · Jul 23, 2024 – Jun 30, 2029 · Role: Principal Investigator
  • Leveraging whole-exome sequence data from diverse biobanks and cohorts to study rare coding variation in prostate cancer
    NIH · R01CA276826 · Sep 20, 2023 – Aug 31, 2028 · Role: Principal Investigator
  • Multiethnic GWAS and TWAS to Inform Risk Prediction for Prostate Cancer
    NIH · U01CA257328 · May 1, 2021 – Apr 30, 2026 · Role: Principal Investigator
  • Multidisciplinary Training in Ethnic Diversity and Cancer Disparities
    NIH · T32CA229110 · Apr 1, 2019 – Mar 31, 2024 · Role: Co-Principal Investigator
  • PAGE III: Population Architecture using Genomics and Epidemiology
    NIH · R56HG010297 · Sep 12, 2018 – Jun 14, 2019 · Role: Co-Principal Investigator
  • Research on Prostate Cancer in Men of African Ancestry: Defining the Roles of Genetics, Immunity and Stress (RESPOND)
    NIH · U19CA214253 · Jul 5, 2018 – Jun 30, 2025 · Role: Principal Investigator
  • Hispanic Latino Lipid Consortium
    NIH · R01HL142302 · May 1, 2018 – Mar 31, 2027 · Role: Co-Principal Investigator
  • Polygenic Risk Prediction of Breast Cancer for Women of African Descent
    NIH · R01CA228198 · Apr 19, 2018 – Jul 1, 2028 · Role: Co-Principal Investigator
  • The Genetic Basis of Aggressive Prostate Cancer: The Role of Rare Variation
    NIH · R01CA196931 · Aug 5, 2016 – Jul 31, 2021 · Role: Principal Investigator
  • African-ancestry Breast Cancer Genetic Consortium
    NIH · R01CA202981 · Jul 1, 2016 – Jul 31, 2030 · Role: Co-Principal Investigator
  • Leveraging ancestral diversity to map adiposity loci in Hispanics
    NIH · R01DK101855 · Aug 15, 2014 – Jul 31, 2019 · Role: Co-Principal Investigator
  • Epidemiologic Studies of Putative Functional Variation in Multiethnic Cohort
    NIH · U01HG007397 · Sep 1, 2013 – Nov 30, 2018 · Role: Principal Investigator
  • Genome-wide sequencing of prostate cancer in men of African ancestry
    NIH · R01CA165862 · Sep 21, 2012 – Jul 31, 2018 · Role: Principal Investigator
  • Understanding Population Differences in Cancer: The MEC Study
    NIH · U01CA164973 · Sep 1, 2012 – Aug 31, 2027 · Role: Co-Principal Investigator
  • Genome-wide association study of breast cancer in high-risk women
    NIH · R01CA165038 · Aug 1, 2012 – May 31, 2019 · Role: Principal Investigator
  • Genome Wide Admixture Scan for Multiple Myeloma in African Americans
    NIH · R01CA134786 · Aug 1, 2010 – May 31, 2017 · Role: Co-Principal Investigator
  • Discovery, Biology and Risk of Inherited Variants in Breast Cancer
    NIH · U19CA148065 · Jul 15, 2010 – Jun 30, 2016 · Role: Co-Principal Investigator
  • Elucidating Loci Involved in Prostate Cancer Suceptibility
    NIH · U19CA148537 · Jul 13, 2010 – Dec 31, 2016 · Role: Co-Principal Investigator
  • Expanding resources for understanding the genetic basis for prostate cancer in Af
    NIH · RC2CA148085 · Sep 30, 2009 – Aug 31, 2012 · Role: Principal Investigator
  • A Multiethnic Genome-Wide Scan of Prostate Cancer
    NIH · U01HG004726 · Sep 20, 2008 – Dec 31, 2011 · Role: Principal Investigator
  • Fine-mapping of 8q24 and Loci Identified in Genome-Wide Studies for Breast &Colo
    NIH · R01CA132839 · Mar 15, 2008 – Feb 28, 2012 · Role: Principal Investigator
  • A Comprehensive Analysis of Genetic Variation in DNA Repair Genes in Relation to
    NIH · R03CA123587 · Aug 1, 2006 – Jul 31, 2008 · Role: Principal Investigator

Publications

  • Multi-ancestry transcriptome-wide association studies uncover insights into breast cancer genetics and biology. Nat Commun. 2026 May 30; 17(1).. View in PubMed
  • Polygenic risk score with KLK3 SNP-SNP interaction pairs for predicting prostate cancer aggressiveness. Commun Med (Lond). 2026 May 28.. View in PubMed
  • Polygenic scores for risk of pancreatic ductal adenocarcinoma: evaluation of novel and published models. NPJ Precis Oncol. 2026 May 27.. View in PubMed
  • An efficient LASSO framework for admixture-aware polygenic scores. HGG Adv. 2026 Jul 09; 7(3):100628.. View in PubMed
  • Meta-analysis of over 8,000 individuals from Hawai’i and Samoa for genetic associations to cardiometabolic phenotypes. medRxiv. 2026 May 12.. View in PubMed
  • African ancestry and risk variants associated with triple-negative breast cancer susceptibility in African American women. Genome Med. 2026 05 07; 18(1).. View in PubMed
  • Sex differences in cancer incidence persist across race and ethnicity. Biol Sex Differ. 2026 04 28; 17(1).. View in PubMed
  • Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries. Lancet Diabetes Endocrinol. 2026 Jul; 14(7):558-569.. View in PubMed
  • Multi ancestry genome wide association meta analysis of urinary aMT6s levels. Sci Rep. 2026 Apr 22; 16(1).. View in PubMed
  • Novel Genetic Risk Loci for Pancreatic Ductal Adenocarcinoma Identified in a Genome-wide Study of African Ancestry Individuals. medRxiv. 2026 Apr 22.. View in PubMed