Christopher P. Gayer, MD, PhD

Associate Professor of Clinical Surgery

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Overview

I am interested in bile acid metabolism and how specific bile acid receptors, such as FXR, influence the intestinal epithelial barrier in injury models

Publications

  • FXR deletion attenuates intestinal barrier dysfunction in murine acute intestinal inflammation. Am J Physiol Gastrointest Liver Physiol. 2024 08 01; 327(2):G175-G187.. View in PubMed
  • Clinical Characteristics of Avoidable Patient Transfers for Suspected Pediatric Appendicitis. J Surg Res. 2024 08; 300:54-62.. View in PubMed
  • Utility of colonic manometry in children with Hirschsprung disease. J Pediatr Gastroenterol Nutr. 2024 06; 78(6):1217-1224.. View in PubMed
  • A Standardized Post-gastrostomy Feeding Protocol for Pediatric Patients Reduces Time to Postoperative Goal Feeding Volume. Am Surg. 2024 Oct; 90(10):2600-2608.. View in PubMed
  • Evaluation of Postoperative Outcomes After Enterostomy Closure in Low Body Weight Infants: A Multi-Center Retrospective Analysis. Am Surg. 2024 Oct; 90(10):2534-2542.. View in PubMed
  • Children with large primary spontaneous pneumothoraxes may benefit from early operative intervention. Pediatr Surg Int. 2022 Mar; 38(3):423-429.. View in PubMed
  • The Pathophysiology of Farnesoid X Receptor (FXR) in the GI Tract: Inflammation, Barrier Function and Innate Immunity. Cells. 2021 11 17; 10(11).. View in PubMed
  • Decreased secondary faecal bile acids in children with ulcerative colitis and Clostridioides difficile infection. Aliment Pharmacol Ther. 2021 09; 54(6):792-804.. View in PubMed
  • Primary Adrenal Malignant Rhabdoid Tumor in a 14-Year-Old Female: A Case Report and Literature Review. Int J Surg Pathol. 2022 Apr; 30(2):172-176.. View in PubMed
  • EP2 Receptor Blockade Attenuates COX-2 Upregulation During Intestinal Inflammation. Shock. 2020 09; 54(3):394-401.. View in PubMed