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Francesca Mariani, PhD

Associate Professor of Stem Cell Biology and Regenerative Medicine

Director for the Stem Cell Biology and Regenerative Medicine Master's Program

Course Director of Stem Cell Biology Regenerative Medicine

Well-being Director, Stem Cell Biology & Regenerative Medicine

Director of Curriculum

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Phone +1 323 442 7855
Email [email protected]
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Overview

Our laboratory studies the development and repair of the mammalian skeleton, with an emphasis on large-scale regeneration of bone and cartilage. To conduct our experiments, we use standard and conditional knock-out techniques in mouse models and in vitro stem and progenitor cell culture.

Publications

  • Ectoderm-mesoderm crosstalk in the embryonic limb: The role of fibroblast growth factor signaling. Dev Dyn. 2017 04; 246(4):208-216.. View in PubMed
  • Prkci is required for a non-autonomous signal that coordinates cell polarity during cavitation. Dev Biol. 2016 08 01; 416(1):82-97.. View in PubMed
  • Ihha induces hybrid cartilage-bone cells during zebrafish jawbone regeneration. Development. 2016 06 15; 143(12):2066-76.. View in PubMed
  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222.. View in PubMed
  • Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway. Stem Cell Reports. 2015 Nov 10; 5(5):866-880.. View in PubMed
  • Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State. Dev Cell. 2015 Nov 09; 35(3):358-65.. View in PubMed
  • Natural large-scale regeneration of rib cartilage in a mouse model. J Bone Miner Res. 2015 Feb; 30(2):297-308.. View in PubMed
  • A surgical procedure for resecting the mouse rib: a model for large-scale long bone repair. J Vis Exp. 2015 Jan 21; (95):52375.. View in PubMed
  • Updated embryology of the upper limb. J Hand Surg Am. 2014 Apr; 39(4):811-2.. View in PubMed
  • Evidence that the limb bud ectoderm is required for survival of the underlying mesoderm. Dev Biol. 2013 Sep 15; 381(2):341-52.. View in PubMed

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