Keck School Faculty

Associations between vascular function and tau PET are associated with global cognition and amyloid J Neurosci. 2020 Oct 12. . View in PubMed

Emotional detachment, gait ataxia, and cerebellar dysconnectivity associated with compound heterozygous mutations in the SPG7 gene Neurocase. 2020 Oct; 26(5):299-304. . View in PubMed

Brain delivery of supplemental docosahexaenoic acid (DHA): A randomized placebo-controlled clinical trial EBioMedicine. 2020 Sep; 59:102883. . View in PubMed

Erythrocyte omega-3 index, ambient fine particle exposure, and brain aging Neurology. 2020 Aug 25; 95(8):e995-e1007. . View in PubMed

Cerebroarterial pulsatility and resistivity indices are associated with cognitive impairment and white matter hyperintensity in elderly subjects: A phase-contrast MRI study J Cereb Blood Flow Metab. 2020 Jun 05; 271678X20927101. . View in PubMed

A novel sensitive assay for detection of a biomarker of pericyte injury in cerebrospinal fluid Alzheimers Dement. 2020 06; 16(6):821-830. . View in PubMed

APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline Nature. 2020 05; 581(7806):71-76. . View in PubMed

Exposure to fine particulate matter and temporal dynamics of episodic memory and depressive symptoms in older women Environ Int. 2020 02; 135:105196. . View in PubMed

Correction: Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline PLoS One. 2020; 15(7):e0236379. . View in PubMed

Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders Alzheimer Dis Assoc Disord. 2019 Oct-Dec; 33(4):327-330. . View in PubMed

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing Nat Genet. 2019 Sep; 51(9):1423-1424. . View in PubMed

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing Nat Genet. 2019 03; 51(3):414-430. . View in PubMed

Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction Nat Med. 2019 02; 25(2):270-276. . View in PubMed

ApoE4 Alters ABCA1 Membrane Trafficking in Astrocytes J Neurosci. 2019 11 27; 39(48):9611-9622. . View in PubMed

General and domain-specific cognitive reserve, mild cognitive impairment, and dementia risk in older women Alzheimers Dement (N Y). 2019; 5:118-128. . View in PubMed

Association of Docosahexaenoic Acid Supplementation With Alzheimer Disease Stage in Apolipoprotein E e4 Carriers: A Review JAMA Neurol. 2017 Mar 01; 74(3):339-347. . View in PubMed

A T1 and DTI fused 3D corpus callosum analysis in MCI subjects with high and low cardiovascular risk profile Neuroimage Clin. 2017; 14:298-307. . View in PubMed

Association of Serum Docosahexaenoic Acid With Cerebral Amyloidosis JAMA Neurol. 2016 Oct 01; 73(10):1208-1216. . View in PubMed

ABCA1-Mediated Cholesterol Efflux Capacity to Cerebrospinal Fluid Is Reduced in Patients With Mild Cognitive Impairment and Alzheimer's Disease J Am Heart Assoc. 2016 Feb 12; 5(2). . View in PubMed

A Multidisciplinary Model of Dementia Care in an Underserved Retirement Community, Made Possible by Telemedicine Front Neurol. 2016; 7:225. . View in PubMed

Consensus statement for diagnosis of subcortical small vessel disease J Cereb Blood Flow Metab. 2016 Jan; 36(1):6-25. . View in PubMed

A Voxel-Based Morphometry Study Reveals Local Brain Structural Alterations Associated with Ambient Fine Particles in Older Women Front Hum Neurosci. 2016; 10:495. . View in PubMed

Differential effects of ischemic vascular disease and Alzheimer's disease on brain atrophy and cognition J Cereb Blood Flow Metab. 2016 Jan; 36(1):204-15. . View in PubMed

Ambient air pollution and neurotoxicity on brain structure: Evidence from women's health initiative memory study Ann Neurol. 2015 Sep; 78(3):466-76. . View in PubMed

A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy JAMA Neurol. 2015 Apr; 72(4):414-22. . View in PubMed

Blood-brain barrier breakdown in the aging human hippocampus Neuron. 2015 Jan 21; 85(2):296-302. . View in PubMed

Clinical and imaging features of mixed Alzheimer and vascular pathologies Alzheimers Res Ther. 2015; 7(1):21. . View in PubMed

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study JAMA Neurol. 2014 Nov; 71(11):1394-404. . View in PubMed

Diagnostic criteria for vascular cognitive disorders: a VASCOG statement Alzheimer Dis Assoc Disord. 2014 Jul-Sep; 28(3):206-18. . View in PubMed

Cortical thickness mediates the effect of ß-amyloid on episodic memory Neurology. 2014 Mar 04; 82(9):761-7. . View in PubMed

APOE associations with severe CAA-associated vasculopathic changes: collaborative meta-analysis J Neurol Neurosurg Psychiatry. 2014 Mar; 85(3):300-5. . View in PubMed

Associations between serum cholesterol levels and cerebral amyloidosis JAMA Neurol. 2014 Feb; 71(2):195-200. . View in PubMed

Change in coping and defense mechanisms across adulthood: longitudinal findings in a European American sample Dev Psychol. 2014 Feb; 50(2):634-48. . View in PubMed

Differences in prefrontal, limbic, and white matter lesion volumes according to cognitive status in elderly patients with first-onset subsyndromal depression PLoS One. 2014; 9(1):e87747. . View in PubMed

10-minute delayed recall from the modified mini-mental state test predicts Alzheimer's disease pathology J Alzheimers Dis. 2014; 39(3):575-82. . View in PubMed

Assessment of cerebrovascular reactivity during resting state breathing and its correlation with cognitive function in hypertension Cerebrovasc Dis. 2014; 38(1):10-6. . View in PubMed

Cerebral atherosclerosis is associated with cystic infarcts and microinfarcts but not Alzheimer pathologic changes Stroke. 2013 Oct; 44(10):2835-41. . View in PubMed

Alzheimer pathology and angiotension receptor blockers JAMA Neurol. 2013 Mar 01; 70(3):414. . View in PubMed

Associations between white matter hyperintensities and ß amyloid on integrity of projection, association, and limbic fiber tracts measured with diffusion tensor MRI PLoS One. 2013; 8(6):e65175. . View in PubMed

Associations among vascular risk factors, carotid atherosclerosis, and cortical volume and thickness in older adults Stroke. 2012 Nov; 43(11):2865-70. . View in PubMed

Coronary risk correlates with cerebral amyloid deposition Neurobiol Aging. 2012 Sep; 33(9):1979-87. . View in PubMed

Different associations of white matter lesions with depression and cognition BMC Neurol. 2012 Aug 25; 12:83. . View in PubMed

Evidence for a role of the rare pA152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet. 2012 Aug 01; 21(15):3500-12. . View in PubMed

Cerebrovascular disease, ß-amyloid, and cognition in agingNeurobiol Aging. 2012 May; 33(5):1006. e25-36. . View in PubMed

Effect of antihypertensive therapy on cognitive function in early executive cognitive impairment: a double-blind randomized clinical trial Arch Intern Med. 2012 Mar 12; 172(5):442-4. . View in PubMed

Coronary artery disease is associated with cognitive decline independent of changes on magnetic resonance imaging in cognitively normal elderly adults J Am Geriatr Soc. 2012 Mar; 60(3):499-504. . View in PubMed

Chinese-language montreal cognitive assessment for cantonese or mandarin speakers: age, education, and gender effects Int J Alzheimers Dis. 2012; 2012:204623. . View in PubMed

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease Nat Genet. 2011 May; 43(5):436-41. . View in PubMed

Association of depressed mood and mortality in older adults with and without cognitive impairment in a prospective naturalistic study Am J Psychiatry. 2010 May; 167(5):589-97. . View in PubMed

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions Nat Genet. 2010 Mar; 42(3):234-9. . View in PubMed

Cerebral blood flow in ischemic vascular dementia and Alzheimer's disease, measured by arterial spin-labeling magnetic resonance imaging Alzheimers Dement. 2009 Nov; 5(6):454-62. . View in PubMed

An inverse association of cardiovascular risk and frontal lobe glucose metabolism Neurology. 2009 Feb 24; 72(8):738-43. . View in PubMed

Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease Arch Neurol. 2008 Dec; 65(12):1640-8. . View in PubMed

Cognitive and anatomic contributions of metabolic decline in Alzheimer disease and cerebrovascular disease Arch Neurol. 2008 May; 65(5):650-5. . View in PubMed

Co-registration of In-Vivo Human MRI Brain Images to Postmortem Histological Microscopic Images Int J Imaging Syst Technol. 2008; 18(5-6):325-335. . View in PubMed

Cognitive and neuroimaging predictors of instrumental activities of daily living J Int Neuropsychol Soc. 2007 Sep; 13(5):747-57. . View in PubMed

A community epidemiological survey of generalized anxiety disorder in Hong Kong Community Ment Health J. 2007 Aug; 43(4):305-19. . View in PubMed

Amyloid imaging in distinguishing atypical prion disease from Alzheimer disease Neurology. 2007 Jul 17; 69(3):283-90. . View in PubMed

Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease Neurology. 2007 Jan 02; 68(1):13-9. . View in PubMed

Cognitive impact of subcortical vascular and Alzheimer's disease pathology Ann Neurol. 2006 Dec; 60(6):677-87. . View in PubMed

Age effects on atrophy rates of entorhinal cortex and hippocampus Neurobiol Aging. 2006 May; 27(5):733-40. . View in PubMed

Advances in vascular cognitive impairment 2005 Stroke. 2006 Feb; 37(2):323-5. . View in PubMed

Cultural diversity in Alzheimer disease: the interface between biology, belief, and behavior Alzheimer Dis Assoc Disord. 2005 Oct-Dec; 19(4):250-5. . View in PubMed

Category fluency in a latino sample: associations with age, education, gender, and language J Clin Exp Neuropsychol. 2005 Jul; 27(5):591-8. . View in PubMed

Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia Ann Neurol. 2005 Jun; 57(6):896-903. . View in PubMed

A standardized method for brain-cutting suitable for both stereology and MRI-brain co-registration J Neurosci Methods. 2004 Oct 30; 139(2):209-15. . View in PubMed

Comparisons between global and focal brain atrophy rates in normal aging and Alzheimer disease: Boundary Shift Integral versus tracing of the entorhinal cortex and hippocampus Alzheimer Dis Assoc Disord. 2004 Oct-Dec; 18(4):196-201. . View in PubMed

A randomized controlled comparison of upper-extremity rehabilitation strategies in acute stroke: A pilot study of immediate and long-term outcomes Arch Phys Med Rehabil. 2004 Apr; 85(4):620-8. . View in PubMed

Higher atrophy rate of entorhinal cortex than hippocampus in AD Neurology. 2004 Feb 10; 62(3):422-7. . View in PubMed

Clinical and neuropsychological features in autopsy-defined vascular dementia Clin Neuropsychol. 2004 Feb; 18(1):63-74. . View in PubMed

Forgetting in dementia with and without subcortical lacunes Clin Neuropsychol. 2004 Feb; 18(1):32-40. . View in PubMed

Different patterns of N-acetylaspartate loss in subcortical ischemic vascular dementia and AD Neurology. 2003 Aug 12; 61(3):358-64. . View in PubMed

Comparison of methods for measuring longitudinal brain change in cognitive impairment and dementia Neurobiol Aging. 2003 Jul-Aug; 24(4):537-44. . View in PubMed

Depression as a risk factor for Alzheimer disease: the MIRAGE Study Arch Neurol. 2003 May; 60(5):753-9. . View in PubMed

Atrophy rates of entorhinal cortex in AD and normal aging Neurology. 2003 Feb 11; 60(3):481-6. . View in PubMed

Effects of subcortical ischemic vascular dementia and AD on entorhinal cortex and hippocampus Neurology. 2002 Jun 11; 58(11):1635-41. . View in PubMed

Executive dysfunction in subcortical ischaemic vascular disease J Neurol Neurosurg Psychiatry. 2002 Feb; 72(2):217-20. . View in PubMed

Dementia due to subcortical ischemic vascular disease Clin Cornerstone. 2001; 3(4):40-51. . View in PubMed

Hippocampal and cortical atrophy predict dementia in subcortical ischemic vascular disease Neurology. 2000 Dec 12; 55(11):1626-35. . View in PubMed

Head injury and the risk of AD in the MIRAGE study Neurology. 2000 Mar 28; 54(6):1316-23. . View in PubMed

Clinical criteria for the diagnosis of vascular dementia: a multicenter study of comparability and interrater reliability Arch Neurol. 2000 Feb; 57(2):191-6. . View in PubMed

Cerebral amyloid angiopathy in Alzheimer disease is associated with apolipoprotein E4 and cortical neuron loss Alzheimer Dis Assoc Disord. 1999 Jan; 13(1):1-8. . View in PubMed

Evaluation of dementia: a systematic study of the usefulness of the American Academy of Neurology's practice parameters Neurology. 1997 Oct; 49(4):925-35. . View in PubMed

Eligibility of Alzheimer's disease clinic patients for clinical trials J Am Geriatr Soc. 1997 Aug; 45(8):923-8. . View in PubMed

Elevated risk of Alzheimer's disease among workers with likely electromagnetic field exposure Neurology. 1996 Dec; 47(6):1477-81. . View in PubMed

Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein E epsilon 4 Am J Hum Genet. 1996 Sep; 59(3):664-75. . View in PubMed

A method to improve interrater reliability of visual inspection of brain MRI scans in dementia Neurology. 1994 Dec; 44(12):2267-76. . View in PubMed

Extrapyramidal signs and psychiatric symptoms predict faster cognitive decline in Alzheimer's disease Arch Neurol. 1994 Jul; 51(7):676-81. . View in PubMed

Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlationsIntraventricular Bethanecol Study Group. Ann Neurol. 1992 Nov; 32(5):625-32. . View in PubMed

Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer's Disease Diagnostic and Treatment Centers Neurology. 1992 Mar; 42(3 Pt 1):473-80. . View in PubMed

Association between vascular basement membrane components and the lesions of Alzheimer's disease J Neurosci Res. 1991 Dec; 30(4):673-81. . View in PubMed

Alzheimer's dementia: performance on parallel forms of the dementia assessment battery J Clin Exp Neuropsychol. 1989 Dec; 11(6):899-912. . View in PubMed

DementiaA review emphasizing clinicopathologic correlation and brain-behavior relationships. Arch Neurol. 1989 Jul; 46(7):806-14. . View in PubMed

Decreased platelet 3H-imipramine binding in Parkinson's disease Biol Psychiatry. 1988 Jul; 24(3):348-51. . View in PubMed

Functional recoveryA major risk factor for the development of postpoliomyelitis muscular atrophy. Arch Neurol. 1988 Jun; 45(6):645-7. . View in PubMed

Alzheimer's dementia: performance on the Mini-Mental State Examination J Consult Clin Psychol. 1987 Feb; 55(1):96-100. . View in PubMed

Clinical subtypes of dementia of the Alzheimer type Neurology. 1985 Nov; 35(11):1544-50. . View in PubMed

CT criteria of hemisphere asymmetry fail to predict language laterality Neurology. 1984 Aug; 34(8):1086-9. . View in PubMed

Brachial plexus involvement in familial pressure-sensitive neuropathy: electrophysiological and morphological findings Ann Neurol. 1980 Dec; 8(6):620-4. . View in PubMed

Computerized tomographic scan findings in patients with autistic behavior Arch Neurol. 1980 Aug; 37(8):504-10. . View in PubMed