Jeannie Chen, PhD

Professor of Physiology and Neuroscience

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Research Funding

Genetically Encoded Probes of Huntingtin Misfolding
NIH · R01NS125769 · Aug 1, 2022 – Jul 31, 2027 · Role: Co-Principal Investigator
Molecular Mechanism of Huntingtin Misfolding and its Inhibition by Designed and Cellular Proteins
NIH · R01NS120704 · Sep 17, 2021 – Aug 31, 2026 · Role: Co-Principal Investigator
Innate Immune IL-10/STAT3 Signaling in Alzheimer's Disease
NIH · RF1AG053982 · Sep 1, 2017 – Mar 31, 2022 · Role: Principal Investigator
CALCIUM HOMEOSTASIS IN MAMMALIAN ROD AND CONE PHOTORECEPTORS
NIH · R01EY027387 · Jul 1, 2017 – Jun 30, 2021 · Role: Co-Principal Investigator
Analyses of retinal circuits after rod rescue in a mouse model of human blindness
NIH · R01EY027193 · Sep 1, 2016 – Aug 31, 2021 · Role: Principal Investigator
Peripheral TGF-beta Pathway Inhibitor Therapy in Alzheimer's Rats
NIH · R01NS076794 · Jun 1, 2011 – May 31, 2022 · Role: Principal Investigator
NEW APPROACHES TO THE MECHANISM AND THERAPY FOR MYASTHENIA GRAVIS
NIH · R21NS061184 · Jun 1, 2008 – Apr 30, 2011 · Role: Principal Investigator
Calcium Feedback Mechanisms in Visual Adaptation
NIH · R01EY012703 · Sep 17, 1999 – Nov 30, 2009 · Role: Principal Investigator
Phototransduction in health and disease
NIH · R01EY012155 · Mar 1, 1998 – Feb 29, 2028 · Role: Principal Investigator
RECOVERIN–VISUAL ADAPTATION AND RETINAL DEGENERATION
NIH · F32EY006405 · Aug 28, 1992 · Role: Principal Investigator

Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration. Exp Eye Res. 2018 02; 167:56-90.. View in PubMed
Separation of photoreceptor cell compartments in mouse retina for protein analysis. Mol Neurodegener. 2017 04 11; 12(1):28.. View in PubMed
Effect of Rhodopsin Phosphorylation on Dark Adaptation in Mouse Rods. J Neurosci. 2016 06 29; 36(26):6973-87.. View in PubMed
Induction of the unfolded protein response by constitutive G-protein signaling in rod photoreceptor cells. J Biol Chem. 2014 Oct 17; 289(42):29310-21.. View in PubMed