Jesse A. Goodrich, PhD

Assistant Professor of Population and Public Health Sciences

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Overview

Dr. Jesse Goodrich is an Assistant Professor in the Division of Environmental Health at the University of Southern California. His research combines data on environmental exposures with information on molecular-level biological processes to understand the effects of environmental pollutants on the risk of obesity, type 2 diabetes, and cancer. He is particularly interested in examining these questions in children and adolescents because they may be more susceptible to the adverse health effects of environmental pollutants.

Research Funding

  • PFAS Exposure and Diabetic Kidney Disease in Youth with Type 2 Diabetes: A Multi-Omic Approach for Prevention and Treatment
    NIH · R01DK140831 · Sep 10, 2024 – Jun 30, 2029 · Role: Principal Investigator
  • PFAS and Diabetic Kidney Disease in Young Onset Type 2 Diabetes: Emerging Risk Factors and Underlying Mechanisms
    NIH · K01ES036193 · Apr 16, 2024 – Mar 31, 2027 · Role: Principal Investigator

Publications

  • Clustering of Omic Data Using Semi-Supervised Transfer Learning for Gaussian Mixture Models via Natural-Gradient Variational Inference: Method and Applications to Bulk and Single-Cell Transcriptomics. bioRxiv. 2025 Nov 14.. View in PubMed
  • Associations between per- and polyfluoroalkyl substances and metabolic dysfunction-associated steatotic liver disease in adolescents and young adults: modifying roles of age, lifestyle factors, and PNPLA3 genotype. Environ Res. 2026 Jan 01; 288(Pt 2):123320.. View in PubMed
  • Ultra-processed food intake is associated with altered glucose homeostasis in young adults with a history of overweight or obesity: a longitudinal study. Nutr Metab (Lond). 2025 Nov 10; 22(1):135.. View in PubMed
  • Mediating role of proteomics in the association between per- and polyfluoroalkyl substance exposure and blood pressure in youth. Environ Pollut. 2025 Dec 15; 387:127336.. View in PubMed
  • Translational framework linking perfluoroheptanoic acid (PFHpA) exposure to metabolic dysfunction associated steatotic liver disease in adolescents. Commun Med (Lond). 2025 Oct 29; 5(1):430.. View in PubMed
  • Plasma Metabolomic and Proteomic Signatures of Blood Pressure Management After Bariatric Surgery Among Adolescents. Hypertension. 2025 Dec; 82(12):2183-2196.. View in PubMed
  • A scoping review on per- and poly-fluoroalkyl substances (PFAS) and colorectal cancer: Evidence from in vitro, animal, and epidemiological studies. Environ Int. 2025 Sep; 203:109778.. View in PubMed
  • Ultra-Processed Food Intake is Associated with Altered Glucose Homeostasis in Young Adults. Res Sq. 2025 Jul 01.. View in PubMed
  • Chrome Plating Facility Siting Is Associated with Neighborhood Demographic and Socioeconomic Factors and Elevated Per- and Polyfluoroalkyl Substances in Blood in California. Environ Sci Technol. 2025 Jul 01; 59(25):12520-12532.. View in PubMed
  • Short-chain per- and polyfluoroalkyl substances associate with elevated alanine aminotransferase: Cross-sectional analysis results from the STRIVE cohort. Environ Res. 2025 Oct 15; 283:122139.. View in PubMed