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Jianfu Chen

Professor of Biomedical Sciences

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Email [email protected]
CTSI Profile

Research Funding

  • Broader Evaluation of TMD Treatment Efficacy and Response (BETTER TMD)
    NIH · U01DE036113 · Sep 11, 2025 – Jun 30, 2030 · Role: Principal Investigator
  • Multiplex meningeal lymphatic activation for Alzheimer?s disease
    NIH · R21AG089268 · Aug 15, 2024 – May 31, 2026 · Role: Principal Investigator
  • Mapping temporomandibular joint (TMJ) degeneration and pain
    NIH · R01DE033511 · Jul 1, 2024 – Apr 30, 2029 · Role: Principal Investigator
  • MSC implantation as a treatment for developmental brain defects in craniosynostosis
    NIH · R01NS136377 · Jun 1, 2024 – May 31, 2029 · Role: Principal Investigator
  • Brain lymphatic activation for craniosynostosis and Alzheimer?s disease
    NIH · RF1NS137467 · Jun 1, 2024 – May 31, 2027 · Role: Principal Investigator
  • Center for TMD IMPACT
    NIH · R34DE033572 · Sep 19, 2023 – Sep 18, 2024 · Role: Co-Principal Investigator
  • Mechanisms and rescue of craniosynostosis associated with gene-environment interaction
    NIH · R01DE030901 · Jul 1, 2021 – Apr 30, 2026 · Role: Principal Investigator
  • Mechanisms regulating neural progenitor expansion in the developing brain
    NIH · R01NS097231 · Sep 1, 2016 – Aug 31, 2021 · Role: Principal Investigator
  • Genetic analysis of a microRNA pathway regulating neural tube closure
    NIH · R01NS096176 · Apr 1, 2016 – Jan 31, 2021 · Role: Principal Investigator
  • Wdr62 in neural development and malformations of cortical development disease
    NIH · R00HD073269 · Aug 1, 2012 – Dec 31, 2017 · Role: Principal Investigator
  • Wdr62 in neural development and malformations of cortical development disease
    NIH · K99HD073269 · Aug 1, 2012 – Jul 31, 2014 · Role: Principal Investigator

Publications

  • MiR-302/367 regulate neural progenitor proliferation, differentiation timing, and survival in neurulation. Dev Biol. 2015 Dec 01; 408(1):140-50.. View in PubMed
  • Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 01; 142(9):1616-27.. View in PubMed
  • Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. Nat Commun. 2014 May 30; 5:3885.. View in PubMed
  • A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice. Dev Neurobiol. 2014 May; 74(5):483-97.. View in PubMed
  • The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev. 2012 Apr 15; 26(8):803-15.. View in PubMed
  • CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res. 2012 Mar 16; 110(6):818-30.. View in PubMed
  • The histone methyltransferase Set7/9 promotes myoblast differentiation and myofibril assembly. J Cell Biol. 2011 Aug 22; 194(4):551-65.. View in PubMed
  • Transgenic overexpression of miR-133a in skeletal muscle. BMC Musculoskelet Disord. 2011 May 26; 12:115.. View in PubMed
  • Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects. Arterioscler Thromb Vasc Biol. 2010 Dec; 30(12):2575-86.. View in PubMed
  • microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. J Cell Biol. 2010 Sep 06; 190(5):867-79.. View in PubMed

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