Mark S. Borchert, MD

Clinical Professor of Ophthalmology (Part-Time)

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Overview

Mark S. Borchert, MD earned a medical degree from Baylor College of Medicine. He completed his residency in the Department of Ophthalmology, University of Southern California, and a fellowship in neuro-ophthalmology at the Massachusetts Eye & Ear Infirmary, Harvard University. Dr. Borchert is the Director of Eye Birth Defects, leading the world’s largest study into optic nerve hypoplasia. Dr. Borchert, who has been listed in “Best Doctors in America,” also has received honors from the Pan American Association of Ophthalmology, the American Academy of Ophthalmology, and Society of Heed Fellows, as well as several teaching awards from the Keck School of Medicine. His research on the development of the retina and optic nerve in rats was part of an experiment on the NASA space shuttle.

Borchert investigates the development of the optic nerve and its retinotopic connections in the tectum (part of the midbrain) and thalamus (part of the forebrain). He is interested in the role that inaccurate or inadequate development of these connections plays in the pathogenesis of optic nerve hypoplasia, the leading cause of blindness in infants in the United states and Europe. His research focus also includes developing diagnostic tools using spectroscopic methods in the measurement of glucose levels in the eye.

Awards

  • Keck School of Medicine of USC: Resident Teaching Award, 1991
     – 1994
  • Keck School of Medicine of USC: Senior Resident Teaching Award, 1994
  • Keck School of Medicine of USC: Resident Teaching Award, 1996
  • Keck School of Medicine of USC: Resident Teaching Award, 1999
  • Keck School of Medicine of USC: Resident Teaching Award, 2001
  • American Academy of Ophthalmology: Achievement Award, 2002
  • America’s Top Doctors, 2006
     – 2009
  • Best Doctors in America Award, 2006
  • Pasadena Magazine Top Doctors Award, 2008
  • LA Magazine Best Doctors in Southern California, 2009
  • Best Doctors in America Award, 2009
  • LA Magazine: Super Doctors Award, 2010
  • Pasadena Magazine Top Doctors Award, 2010
  • Pasadena Magazine Top Doctors Award, 2013
     – 2014

Education and Training

  • Baylor College of Medicine — MD — 1983
  • USC Roski Eye Institute — Ophthalmology Residency — 1987
  • Massachusetts Eye & Ear Infirmary — Neuro-Ophthalmology Fellowship — 1988

Publications

  • Long-term outcomes of pediatric ocular myasthenia gravis. Ophthalmology. 2008 Jul; 115(7):1245-1248.e1.. View in PubMed
  • Review of the pleiotropic effects of peroxisome proliferator-activated receptor gamma agonists on platelet function. Diabetes Technol Ther. 2007 Oct; 9(5):410-20.. View in PubMed
  • Visual acuity testability in African-American and Hispanic children: the multi-ethnic pediatric eye disease study. Am J Ophthalmol. 2007 Nov; 144(5):663-7.. View in PubMed
  • Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report. Blood. 2007 Jan 15; 109(2):503-6.. View in PubMed
  • Retinal function in infants with optic nerve hypoplasia: electroretinograms to large patterns and photopic flash. Eye (Lond). 2007 Jun; 21(6):712-20.. View in PubMed
  • Measurement of amphotericin B concentration by resonant Raman spectroscopy–a novel technique that may be useful for non-invasive monitoring. Med Mycol. 2006 Mar; 44(2):169-74.. View in PubMed
  • Validation of ICNIRP estimates of toxicity thresholds for NIR (785 nm) light in the retinas of pigmented rabbits. Health Phys. 2006 Jan; 90(1):3-10.. View in PubMed
  • Endocrinological and auxological abnormalities in young children with optic nerve hypoplasia: a prospective study. J Pediatr. 2006 Jan; 148(1):78-84.. View in PubMed
  • Determination of glucose in human aqueous humor using Raman spectroscopy and designed-solution calibration. Appl Spectrosc. 2005 Aug; 59(8):1024-31.. View in PubMed
  • Glucose determination in human aqueous humor with Raman spectroscopy. J Biomed Opt. 2005 May-Jun; 10(3):031110.. View in PubMed