Mark S. Humayun, MD, PhD

University Professor of Ophthalmology

Cornelius J. Pings Chair in Biomedical Sciences

Director, USC Ginsberg Institute for Biomedical Therapeutics

Co-Director USC Roski Eye Institute

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Overview

Mark S. Humayun, MD, PhD, received his Bachelors of Science degree from Georgetown University in 1984, his Doctor of Medicine (MD) from Duke University in 1989, and his PhD from the University of North Carolina, Chapel Hill in 1994. He completed his ophthalmology residency at Duke Eye Center and fellowships in both vitreoretinal and retinovascular surgery at Johns Hopkins Hospital. He stayed on as faculty at Johns Hopkins where he rose to the rank of associate professor before moving to USC in 2001.

Dr. Humayun has devoted much of his career to clinical and scientific research in ophthalmology and bioengineering, becoming both a biomedical engineer and professor of ophthalmology. Dr. Humayun led a talented and diverse team of interdisciplinary researchers with the ultimate goal of creating the world’s first artificial retina. He assembled a team of world experts with a wide range of proficiency, including biomedical engineering, computer science, medicine, chemistry, biology and business. In clinical trials since 2007 and approved by the FDA in 2013, the Argus II retinal implant, represents the culmination of a visual restoration strategy that offers an unprecedented degree of sight to those with complete retinal blindness. He was elected to the prestigious National Academy of Medicine (NAM) and National Academy of Engineering (NAE) for his pioneering work to restore sight.

With over 300 publications and more than 140 patents and patent applications, Dr. Humayun has received several research awards which includes the 2005 Innovator of the Year award. He was also featured as one of the top 10 inventors in Time Magazine in 2013, voted as one of the Best Doctors in America for three years, and one of the top 1% of Doctors by U.S. News & World Report.

In 2016, Dr. Humayun received the National Medal of Technology and Innovation from President Barack Obama for his innovative work and development of the Argus II.

Awards

  • USC Roski Eye Institute: Narsing A. Rao, MD Endowed Lecture Award, 2022
  • Association for Research in Vision and Ophthalmology: ARVO Fellows Class of 2022, 2022
  • American Association for the Advancement of Science: American Association for the Advancement of Science (AAAS) Fellow, 2022
  • Super Doctors Southern California Magazine: Southern California Super Doctors, 2021
  • Retina Research Foundation: Retina Research Foundation Award of Merit (The Schepens Lecture), 2021
  • USC Stevens Center for Innovation: 2020 Technology Commercialization Award, 2021
  • American Society of Retina Specialists: Gertrude D. Pyron Award, 2020
  • European Vitreo Retinal Society: The Relja Zivojnovic Award, 2020
  • Institute of Electrical and Electronics Engineers: 2020 IEEE Medal for Innovations in Healthcare Technology, 2020
  • Duke Medical Alumni Association: Distinguished Alumnus Award, 2019
  • Georgetown University: Doctor of Humane Letters, Honoris Causa, 2019
  • University of Southern California: USC Stevens Center Commercialization Award, 2019
  • Farabi Eye Hospital: 2018 Persian Ophthalmologist, 2018
  • Future Vision Foundation: 2018 Future Vision Award, 2018
  • Eye and Ear Foundation, University of Pittsburgh: 2018 Muse Prize in Ophthalmology, 2018
  • Institute of Electrical and Electronics Engineers: IEEE Biomedical Engineering Award, 2018
  • National Academy of Inventors Fellows Medallion, 2017
  • USC Presidential Medallion, 2017
  • National Medal of Technology and Innovation, 2016
  • Wills Eye Institute: Richard Ellis Award, 2014
  • Pasadena Magazine: Top Doctors in Ophthalmology, 2013-2014
  • UIC Illinois Eye and Ear Infirmary: Morton F. Goldberg Endowed Lecturer Medallion, 2013
  • U.S. World & News Report: Top 1% of Ophthalmologists, 2011
  • Castle Connolly Medical Ltd. : America’s Top Doctors, 2011
  • Popular Mechanics Breakthrough Award, 2010
  • The Retina Society: Award of Merit in Retina Research, 2009
  • Best Doctors in Southern California Award, 2009
  • Best Doctors of America Award, 2005-2007
  • Strathmore’s Who’s Who Award, 2005-2006
  • R&D magazine: Innovator of the Year award, 2005
  • Senior Honor Award of the Am. Soc. Retina Specialists, 2004
  • Jules Stein Living tribute Award, 2002
  • William and Mary Grieve Scholar’s Award, 1997-1998
  • Richard S. Ross Clinical Scientist Award, 1997-1998

Publications

  • Scaling up polarized RPE cell supernatant production on parylene membrane Exp Eye Res. 2024 Mar; 240:109789. . View in PubMed
  • Integrating a Fundus Camera with High-Frequency Ultrasound for Precise Ocular Lesion Assessment Biosensors (Basel). 2024 Feb 29; 14(3). . View in PubMed
  • Loss of 15-Lipoxygenase in Retinodegenerative RCS Rats Int J Mol Sci. 2024 Feb 15; 25(4). . View in PubMed
  • Hydroxypropyl-Beta Cyclodextrin Barrier Prevents Respiratory Viral Infections: A Preclinical Study Int J Mol Sci. 2024 Feb 08; 25(4). . View in PubMed
  • Long-term Follow-up of a Phase 1/2a Clinical Trial of a Stem Cell-Derived Bioengineered Retinal Pigment Epithelium Implant for Geographic Atrophy Ophthalmology. 2023 Dec 30. . View in PubMed
  • Author Correction: An extraocular electrical stimulation approach to slow down the progression of retinal degeneration in an animal model Sci Rep. 2023 Oct 23; 13(1):18120. . View in PubMed
  • Gaps and future of human-centered artificial intelligence in ophthalmology: Future Vision Forum consensus statement Curr Opin Ophthalmol. 2023 Sep 01; 34(5):431-436. . View in PubMed
  • Non-Invasive Hybrid Ultrasound Stimulation of Visual Cortex In Vivo Bioengineering (Basel). 2023 May 10; 10(5). . View in PubMed
  • Ultrasound Concave 2-D Ring Array for Retinal Stimulation IEEE Trans Ultrason Ferroelectr Freq Control. 2023 11; 70(11):1527-1535. . View in PubMed
  • Simultaneous Assessment of the Whole Eye Biomechanics Using Ultrasonic Elastography IEEE Trans Biomed Eng. 2023 04; 70(4):1310-1317. . View in PubMed
  • An extraocular electrical stimulation approach to slow down the progression of retinal degeneration in an animal model Sci Rep. 2023 09 23; 13(1):15924. . View in PubMed
  • Computational optimization of delivery parameters to guide the development of targeted Nasal spray Sci Rep. 2023 03 12; 13(1):4099. . View in PubMed
  • Polarized RPE Secretome Preserves Photoreceptors in Retinal Dystrophic RCS Rats Cells. 2023 06 22; 12(13). . View in PubMed
  • Development of a Surgical Technique for Subretinal Implants in Rats J Vis Exp. 2022 Dec 02; (190). . View in PubMed
  • Design and Simulation of a Ring Transducer Array for Ultrasound Retinal Stimulation Micromachines (Basel). 2022 Sep 16; 13(9). . View in PubMed
  • Mathematical Model of Macromolecular Drug Transport in a Partially Liquefied Vitreous Humor J Heat Transfer. 2022 Mar 01; 144(3):031208. . View in PubMed
  • Ultrasound Retinal Stimulation: A Mini-Review of Recent Developments IEEE Trans Ultrason Ferroelectr Freq Control. 2022 12; 69(12):3224-3231. . View in PubMed
  • Advanced Retina Implants Ophthalmol Retina. 2022 10; 6(10):899-905. . View in PubMed
  • Super-Resolution Ultrasound Localization Microscopy for Visualization of the Ocular Blood Flow IEEE Trans Biomed Eng. 2022 05; 69(5):1585-1594. . View in PubMed
  • Focused ultrasound stimulation on meibomian glands for the treatment of evaporative dry eye Exp Biol Med (Maywood). 2022 03; 247(6):519-526. . View in PubMed
  • Flexible ultrasound-induced retinal stimulating piezo-arrays for biomimetic visual prostheses Nat Commun. 2022 07 04; 13(1):3853. . View in PubMed
  • Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration Stem Cell Reports. 2022 03 08; 17(3):448-458. . View in PubMed
  • Development of Moderate Intensity Focused Ultrasound (MIFU) for Ocular Drug Delivery BME Front. 2022; 2022:9840678. . View in PubMed
  • Noninvasive Ultrasound Retinal Stimulation for Vision Restoration at High Spatiotemporal Resolution BME Front. 2022; 2022:9829316. . View in PubMed
  • Selective Activation of Retinal Ganglion Cell Subtypes Through Targeted Electrical Stimulation Parameters IEEE Trans Neural Syst Rehabil Eng. 2022; 30:350-359. . View in PubMed
  • Analytical and Computational Modeling of Sustained-Release Drug Implants in the Vitreous Humor J Heat Transfer. 2021 Oct 01; 143(10):101201. . View in PubMed
  • Publisher Correction: Color and cellular selectivity of retinal ganglion cell subtypes through frequency modulation of electrical stimulation Sci Rep. 2021 Jun 14; 11(1):12855. . View in PubMed
  • Electronic retinal prosthesis for severe loss of vision in geographic atrophy in age-related macular degeneration: First-in-human use Eur J Ophthalmol. 2021 May; 31(3):920-931. . View in PubMed
  • In Vivo Experimental and Analytical Studies for Bevacizumab Diffusion Coefficient Measurement in the Rabbit Vitreous Humor J Heat Transfer. 2021 Mar 01; 143(3):032101. . View in PubMed
  • High resolution optical coherence elastography of retina under prosthetic electrode Quant Imaging Med Surg. 2021 Mar; 11(3):918-927. . View in PubMed
  • Tissue Engineering Strategies for Retina Regeneration Appl Sci (Basel). 2021 Mar; 11(5). . View in PubMed
  • Novel probabilistic model of core vitreous traction using microsurgical vitrectomy tools Graefes Arch Clin Exp Ophthalmol. 2021 Feb; 259(2):405-412. . View in PubMed
  • Ultrasonic elastography to assess biomechanical properties of the optic nerve head and peripapillary sclera of the eye Ultrasonics. 2021 Feb; 110:106263. . View in PubMed
  • NAP1051, a Lipoxin A4 Biomimetic Analogue, Demonstrates Antitumor Activity Against the Tumor Microenvironment Mol Cancer Ther. 2021 12; 20(12):2384-2397. . View in PubMed
  • Modeling ON Cone Bipolar Cells for Electrical Stimulation Annu Int Conf IEEE Eng Med Biol Soc. 2021 11; 2021:6547-6550. . View in PubMed
  • On the Design of an Efficient Inductive Wireless Power Transfer for Passive Neurostimulation Systems Annu Int Conf IEEE Eng Med Biol Soc. 2021 11; 2021:7497-7501. . View in PubMed
  • Restoring Color Perception to the Blind: An Electrical Stimulation Strategy of Retina in Patients with End-stage Retinitis Pigmentosa Ophthalmology. 2021 03; 128(3):453-462. . View in PubMed
  • Transcranial Focused Ultrasound for Noninvasive Neuromodulation of the Visual Cortex IEEE Trans Ultrason Ferroelectr Freq Control. 2021 01; 68(1):21-28. . View in PubMed
  • First Human Results With the 256 Channel Intelligent Micro Implant Eye (IMIE 256) Transl Vis Sci Technol. 2021 08 12; 10(10):14. . View in PubMed
  • Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo Sci Rep. 2021 03 18; 11(1):6286. . View in PubMed
  • One-Year Anatomical and Functional Outcomes of the Argus II Implantation in Korean Patients with Late-Stage Retinitis Pigmentosa: A Prospective Case Series Study Ophthalmologica. 2021; 244(4):291-300. . View in PubMed
  • Mechanisms underlying activation of retinal bipolar cells through targeted electrical stimulation: a computational study J Neural Eng. 2021 12 15; 18(6). . View in PubMed
  • Layer-specific ultrasound elastography using a multi-layered shear wave dispersion model for assessing the viscoelastic properties Phys Med Biol. 2021 01 26; 66(3):035003. . View in PubMed
  • Color and cellular selectivity of retinal ganglion cell subtypes through frequency modulation of electrical stimulation Sci Rep. 2021 03 04; 11(1):5177. . View in PubMed
  • One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration Transl Vis Sci Technol. 2021 08 12; 10(10):13. . View in PubMed
  • Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats Front Neurosci. 2021; 15:752958. . View in PubMed
  • Blocking Ocular Sympathetic Activity Inhibits Choroidal Neovascularization Front Neurosci. 2021; 15:780841. . View in PubMed
  • Long-Term Transplant Effects of iPSC-RPE Monolayer in Immunodeficient RCS Rats Cells. 2021 10 29; 10(11). . View in PubMed
  • Ultrasonic Retinal Neuromodulation and Acoustic Retinal Prosthesis Micromachines (Basel). 2020 Oct 13; 11(10). . View in PubMed
  • ADVERSE EVENTS OF THE ARGUS II RETINAL PROSTHESIS: Incidence, Causes, and Best Practices for Managing and Preventing Conjunctival Erosion Retina. 2020 Feb; 40(2):303-311. . View in PubMed
  • Targeted Stimulation of Retinal Ganglion Cells in Epiretinal Prostheses: A Multiscale Computational Study IEEE Trans Neural Syst Rehabil Eng. 2020 11; 28(11):2548-2556. . View in PubMed
  • In Vivo Visualization of Eye Vasculature Using Super-Resolution Ultrasound Microvessel Imaging IEEE Trans Biomed Eng. 2020 10; 67(10):2870-2880. . View in PubMed
  • Responsiveness of Retinal Ganglion Cells Through Frequency Modulation of Electrical Stimulation: A Computational Modeling Study Annu Int Conf IEEE Eng Med Biol Soc. 2020 07; 2020:3393-3398. . View in PubMed
  • Hypotony and the Argus II retinal prosthesis: causes, prevention and management Br J Ophthalmol. 2020 04; 104(4):518-523. . View in PubMed
  • Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study Ophthalmol Retina. 2020 03; 4(3):264-273. . View in PubMed
  • In vivo evaluation of posterior eye elasticity using shaker-based optical coherence elastography Exp Biol Med (Maywood). 2020 02; 245(4):282-288. . View in PubMed
  • Cyanine Nanocages Activated by Near-Infrared Light for the Targeted Treatment of Traumatic Brain Injury Front Chem. 2020; 8:769. . View in PubMed
  • Retina-electrode interface properties and vision restoration by two generations of retinal prostheses in one patient-one in each eye J Neural Eng. 2020 04 09; 17(2):026020. . View in PubMed
  • Economic Value of Anti-Vascular Endothelial Growth Factor Treatment for Patients With Wet Age-Related Macular Degeneration in the United States JAMA Ophthalmol. 2020 01 01; 138(1):40-47. . View in PubMed
  • Cyanine Nanocage Activated by Near-IR Light for the Targeted Delivery of Cyclosporine A to Traumatic Brain Injury Sites Mol Pharm. 2020 12 07; 17(12):4499-4509. . View in PubMed
  • MEASUREMENT OF THE HYDRAULIC CONDUCTIVITY OF THE VITREOUS HUMOR J Porous Media. 2020; 23(2):195-206. . View in PubMed
  • Quantitative confocal optical coherence elastography for evaluating biomechanics of optic nerve head using Lamb wave model Neurophotonics. 2019 Oct; 6(4):041112. . View in PubMed
  • Evaluating New Ophthalmic Digital Devices for Safety and Effectiveness in the Context of Rapid Technological Development JAMA Ophthalmol. 2019 Aug 01; 137(8):939-944. . View in PubMed
  • Diffusive Transport in the Vitreous Humor: Experimental and Analytical Studies J Heat Transfer. 2019 May; 141(5):050801. . View in PubMed
  • Histopathologic Assessment of Optic Nerves and Retina From a Patient With Chronically Implanted Argus II Retinal Prosthesis System Transl Vis Sci Technol. 2019 May; 8(3):31. . View in PubMed
  • A Novel Racing Array Transducer for Noninvasive Ultrasonic Retinal Stimulation: A Simulation Study Sensors (Basel). 2019 Apr 17; 19(8). . View in PubMed
  • Flexible piezoelectric ultrasonic energy harvester array for bio-implantable wireless generator Nano Energy. 2019 Feb; 56:216-224. . View in PubMed
  • Ultrasonic Microelastography to Assess Biomechanical Properties of the Cornea IEEE Trans Biomed Eng. 2019 03; 66(3):647-655. . View in PubMed
  • Thomas ASwift’s Electric Rifle Injuries to the Eye and Ocular Adnexa: The Management of Complex Trauma. Ophthalmol Retina. 2019 03; 3(3):258-269. . View in PubMed
  • Sympathetic Effects of Internal Carotid Nerve Manipulation on Choroidal Vascularity and Related Measures Invest Ophthalmol Vis Sci. 2019 10 01; 60(13):4303-4309. . View in PubMed
  • Enhanced Depth Navigation Through Augmented Reality Depth Mapping in Patients with Low Vision Sci Rep. 2019 08 02; 9(1):11230. . View in PubMed
  • Subretinal Implantation of a Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium Monolayer in a Porcine Model Adv Exp Med Biol. 2019; 1185:569-574. . View in PubMed
  • Argus II Retinal Prosthesis Implantation in a Patient With a History Of Strabismus Surgery:A Surgical Technique Ophthalmic Surg Lasers Imaging Retina. 2019 02 01; 50(2):116-119. . View in PubMed
  • A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells Graefes Arch Clin Exp Ophthalmol. 2018 Nov; 256(11):2113-2125. . View in PubMed
  • VISUAL AND ANATOMICAL OUTCOMES AFTER DIABETIC TRACTION AND TRACTION-RHEGMATOGENOUS RETINAL DETACHMENT REPAIR Retina. 2018 Oct; 38(10):1913-1919. . View in PubMed
  • Quantified elasticity mapping of retinal layers using synchronized acoustic radiation force optical coherence elastography Biomed Opt Express. 2018 Sep 01; 9(9):4054-4063. . View in PubMed
  • Chronically Implantable Package Based on Alumina Ceramics and Titanium with High-density Feedthroughs for Medical Implants Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:3382-3385. . View in PubMed
  • Implantation of multiple suprachoroidal electrode arrays in rabbits J Curr Ophthalmol. 2018 Mar; 30(1):68-73. . View in PubMed
  • Development of a KNN Ceramic-Based Lead-Free Linear Array Ultrasonic Transducer IEEE Trans Ultrason Ferroelectr Freq Control. 2018 11; 65(11):2113-2120. . View in PubMed
  • Retinal Anatomy and Electrode Array Position in Retinitis Pigmentosa Patients After Argus II Implantation: An International Study Am J Ophthalmol. 2018 09; 193:87-99. . View in PubMed
  • Increasing Electrical Stimulation Efficacy in Degenerated Retina: Stimulus Waveform Design in a Multiscale Computational Model IEEE Trans Neural Syst Rehabil Eng. 2018 06; 26(6):1111-1120. . View in PubMed
  • Temporal Neuromodulation of Retinal Ganglion Cells by Low-Frequency Focused Ultrasound Stimulation IEEE Trans Neural Syst Rehabil Eng. 2018 05; 26(5):969-976. . View in PubMed
  • High-Performance Ultrasound Needle Transducer Based on Modified PMN-PT Ceramic With Ultrahigh Clamped Dielectric Permittivity IEEE Trans Ultrason Ferroelectr Freq Control. 2018 02; 65(2):223-230. . View in PubMed
  • Stereological Method in Optical Coherence Tomography for In Vivo Evaluation of Laser-Induced Choroidal Neovascularization Ophthalmic Surg Lasers Imaging Retina. 2018 09 01; 49(9):e65-e74. . View in PubMed
  • A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration Sci Transl Med. 2018 04 04; 10(435). . View in PubMed
  • Disintegrin-Integrin Binding for Attachment of Polymer Substrate to the Retina J Clin Exp Ophthalmol. 2018; 9(5). . View in PubMed
  • A reversible thermoresponsive sealant for temporary closure of ocular trauma Sci Transl Med. 2017 Dec 06; 9(419). . View in PubMed
  • Flexible microelectrode array for retinal prosthesis Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul; 2017:1097-1100. . View in PubMed
  • High-performance iridium oxide/platinum nano-leaf composite coatings on microelectrodes for neural stimulation/recording Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul; 2017:1070-1073. . View in PubMed
  • Parylene scaffold for cartilage lesion Biomed Microdevices. 2017 06; 19(2):26. . View in PubMed
  • THE SECOND BLIND SPOT: SMALL RETINAL VESSEL VASCULOPATHY AFTER VACCINATION AGAINST NEISSERIA MENINGITIDIS AND YELLOW FEVER Retin Cases Brief Rep. 2017 Winter; 11 Suppl 1:S18-S23. . View in PubMed
  • Development of a new tissue injector for subretinal transplantation of human embryonic stem cell derived retinal pigmented epithelium Int J Retina Vitreous. 2017; 3:41. . View in PubMed
  • Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models Stem Cells Int. 2017; 2017:9428176. . View in PubMed
  • Positive Visual Phenomena Following Implantation of the Argus II Retinal Prosthesis Ophthalmic Surg Lasers Imaging Retina. 2017 12 01; 48(12):1022-1025. . View in PubMed
  • The Bionic Eye: A Quarter Century of Retinal Prosthesis Research and Development Ophthalmology. 2016 Oct; 123(10S):S89-S97. . View in PubMed
  • Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs Graefes Arch Clin Exp Ophthalmol. 2016 Aug; 254(8):1553-1565. . View in PubMed
  • Strategies to improve stimulation efficiency for retinal prostheses Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug; 2016:3133-3138. . View in PubMed
  • INTRAOCULAR PRESSURE CHANGES DURING VITRECTOMY USING CONSTELLATION VISION SYSTEM’S INTRAOCULAR PRESSURE CONTROL FEATURE Retina. 2016 Jul; 36(7):1275-80. . View in PubMed
  • An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results Ophthalmic Surg Lasers Imaging Retina. 2016 Apr 01; 47(4):342-51. . View in PubMed
  • NorLeu3A(1-7) Accelerates Clear Corneal Full Thickness Wound Healing Invest Ophthalmol Vis Sci. 2016 Apr 01; 57(4):2187-94. . View in PubMed
  • Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial Ophthalmology. 2016 10; 123(10):2248-54. . View in PubMed
  • Retinal stimulation strategies to restore vision: Fundamentals and systems Prog Retin Eye Res. 2016 07; 53:21-47. . View in PubMed
  • Biomimetic Accommodating Intraocular Lens Using a Valved Deformable Liquid Balloon IEEE Trans Biomed Eng. 2016 06; 63(6):1129-35. . View in PubMed
  • Electrical Stimulation of the Retina to Produce Artificial Vision Annu Rev Vis Sci. 2016 10 14; 2:273-294. . View in PubMed
  • Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats Invest Ophthalmol Vis Sci. 2016 05 01; 57(6):2877-87. . View in PubMed
  • Spatial Variations in Vitreous Oxygen Consumption PLoS One. 2016; 11(3):e0149961. . View in PubMed
  • OPTOMAP WIDEFIELD IMAGING OF THE ARGUS II RETINAL PROSTHESIS IN PATIENTS WITH RETINITIS PIGMENTOSA Retin Cases Brief Rep. 2016; 10(4):382-5. . View in PubMed
  • Improving the spatial resolution of epiretinal implants by increasing stimulus pulse duration Sci Transl Med. 2015 Dec 16; 7(318):318ra203. . View in PubMed
  • Ten-Year Follow-up of a Blind Patient Chronically Implanted with Epiretinal Prosthesis Argus IOphthalmology. 2015 Dec; 122(12):2545-52. e1. . View in PubMed
  • Stem cell based therapies for age-related macular degeneration: The promises and the challenges Prog Retin Eye Res. 2015 Sep; 48:1-39. . View in PubMed
  • Monte Carlo analysis of the enhanced transcranial penetration using distributed near-infrared emitter array J Biomed Opt. 2015 Aug; 20(8):88001. . View in PubMed
  • Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind Ophthalmology. 2015 Aug; 122(8):1547-54. . View in PubMed
  • Whole vitreous humor dissection for vitreodynamic analysis J Vis Exp. 2015 May 24; (99):e52759. . View in PubMed
  • Fluidics comparison between dual pneumatic and spring return high-speed vitrectomy systems Ophthalmic Surg Lasers Imaging Retina. 2015 Jan; 46(1):68-72. . View in PubMed
  • Implantable MicroPump for Drug Delivery in Patients with Diabetic Macular Edema Transl Vis Sci Technol. 2014 Oct; 3(6):5. . View in PubMed
  • Noninvasive assessment of retinal vascular oxygen content among normal and diabetic human subjects: a study using hyperspectral computed tomographic imaging spectroscopy Retina. 2014 Sep; 34(9):1854-60. . View in PubMed
  • Elastic properties of human posterior eye J Biomed Mater Res A. 2014 Jun; 102(6):2001-7. . View in PubMed
  • Retinal prosthesis IEEE Trans Biomed Eng. 2014 May; 61(5):1412-24. . View in PubMed
  • One-Year Feasibility Study of Replenish MicroPump for Intravitreal Drug Delivery: A Pilot Study Transl Vis Sci Technol. 2014 May; 3(4):8. . View in PubMed
  • Interphase gap as a means to reduce electrical stimulation thresholds for epiretinal prostheses J Neural Eng. 2014 Feb; 11(1):016007. . View in PubMed
  • Profile of ocriplasmin and its potential in the treatment of vitreomacular adhesion Clin Ophthalmol. 2014; 8:847-56. . View in PubMed
  • Comparison of reaction response time between hand and foot controlled devices in simulated microsurgical testing Biomed Res Int. 2014; 2014:769296. . View in PubMed
  • Microdevice-based cell therapy for age-related macular degeneration Dev Ophthalmol. 2014; 53:155-66. . View in PubMed
  • A fully intraocular high-density self-calibrating epiretinal prosthesis IEEE Trans Biomed Circuits Syst. 2013 Dec; 7(6):747-60. . View in PubMed
  • Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer Invest Ophthalmol Vis Sci. 2013 Jul 26; 54(7):5087-96. . View in PubMed
  • In vivo detection of hESC-RPE cells via confocal near-infrared fundus reflectance Ophthalmic Surg Lasers Imaging Retina. 2013 Jul-Aug; 44(4):380-4. . View in PubMed
  • A system verification platform for high-density epiretinal prostheses IEEE Trans Biomed Circuits Syst. 2013 Jun; 7(3):326-37. . View in PubMed
  • The Argus II epiretinal prosthesis system allows letter and word reading and long-term function in patients with profound vision loss Br J Ophthalmol. 2013 May; 97(5):632-6. . View in PubMed
  • Analysis of a 23-gauge ultra high-speed cutter with duty cycle control Retina. 2013 May; 33(5):933-8. . View in PubMed
  • Performance analysis of ultrahigh-speed vitreous cutter system Retina. 2013 May; 33(5):928-32. . View in PubMed
  • Light-triggered modulation of cellular electrical activity by ruthenium diimine nanoswitches ACS Chem Neurosci. 2013 Apr 17; 4(4):585-93. . View in PubMed
  • Factors Affecting Perceptual Threshold in Argus II Retinal Prosthesis Subjects Transl Vis Sci Technol. 2013 Apr; 2(4):1. . View in PubMed
  • Performance of visually guided tasks using simulated prosthetic vision and saliency-based cues J Neural Eng. 2013 Apr; 10(2):026017. . View in PubMed
  • Imaging the response of the retina to electrical stimulation with genetically encoded calcium indicators J Neurophysiol. 2013 Apr; 109(7):1979-88. . View in PubMed
  • Quantitative analysis of retinal structures using spectral domain optical coherence tomography in normal rabbits Curr Eye Res. 2013 Feb; 38(2):299-304. . View in PubMed
  • In vivo Sonothrombolysis of Ear Marginal Vein of Rabbits Monitored with High-frequency Ultrasound Needle Transducer J Med Biol Eng. 2013; 33(1):103-110. . View in PubMed
  • Fluidics in a dual pneumatic ultra high-speed vitreous cutter system Ophthalmologica. 2013; 229(1):15-20. . View in PubMed
  • High-resolution OCT: an innovative tool for posterior segment imaging Ophthalmic Surg Lasers Imaging. 2012 Nov-Dec; 43(6 Suppl):S123-34. . View in PubMed
  • Evaluation of ultrasound-assisted thrombolysis using custom liposomes in a model of retinal vein occlusion Invest Ophthalmol Vis Sci. 2012 Oct 05; 53(11):6920-7. . View in PubMed
  • Fluorescein angiography, optical coherence tomography, and histopathologic findings in a VEGF(165) animal model of retinal angiogenesis Graefes Arch Clin Exp Ophthalmol. 2012 Oct; 250(10):1421-8. . View in PubMed
  • Mesh-supported submicron parylene-C membranes for culturing retinal pigment epithelial cells Biomed Microdevices. 2012 Aug; 14(4):659-67. . View in PubMed
  • Artificial vision through neuronal stimulation Neurosci Lett. 2012 Jun 25; 519(2):122-8. . View in PubMed
  • Response to ‘technology for mobility in SCI ten years from now’ Spinal Cord. 2012 May; 50(5):364. . View in PubMed
  • Preservation of retinotopic map in retinal degeneration Exp Eye Res. 2012 May; 98:88-96. . View in PubMed
  • Interim results from the international trial of Second Sight’s visual prosthesis Ophthalmology. 2012 Apr; 119(4):779-88. . View in PubMed
  • Assessment of MRI issues for the Argus II retinal prosthesis Magn Reson Imaging. 2012 Apr; 30(3):382-9. . View in PubMed
  • Frequency and amplitude modulation have different effects on the percepts elicited by retinal stimulation Invest Ophthalmol Vis Sci. 2012 Jan 20; 53(1):205-14. . View in PubMed
  • A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer Ophthalmic Res. 2012; 48(4):186-91. . View in PubMed
  • Acute variations in retinal vascular oxygen content in a rabbit model of retinal venous occlusion PLoS One. 2012; 7(11):e50179. . View in PubMed
  • Impedance as a method to sense proximity at the electrode-retina interface IEEE Trans Neural Syst Rehabil Eng. 2011 Dec; 19(6):696-9. . View in PubMed
  • Retinal prostheses: current clinical results and future needs Ophthalmology. 2011 Nov; 118(11):2227-37. . View in PubMed
  • Continuous electrical stimulation decreases retinal excitability but does not alter retinal morphology J Neural Eng. 2011 Aug; 8(4):045003. . View in PubMed
  • Resolution of the epiretinal prosthesis is not limited by electrode size IEEE Trans Neural Syst Rehabil Eng. 2011 Aug; 19(4):436-42. . View in PubMed
  • Modeling and percept of transcorneal electrical stimulation in humans IEEE Trans Biomed Eng. 2011 Jul; 58(7):1932-9. . View in PubMed
  • Morphometric analysis of optic nerves and retina from an end-stage retinitis pigmentosa patient with an implanted active epiretinal array Invest Ophthalmol Vis Sci. 2011 Jun 28; 52(7):4610-6. . View in PubMed
  • Both electrical stimulation thresholds and SMI-32-immunoreactive retinal ganglion cell density correlate with age in S334ter line 3 rat retina J Neurophysiol. 2011 Jun; 105(6):2687-97. . View in PubMed
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