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Marlena Fejzo, PhD

Clinical Assistant Professor of Population and Public Health Sciences in the Center for Genetic Epidemiology

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Overview

Marlena Fejzo is a Harvard-trained women’s health scientist who has published peer-reviewed articles on many diseases of women including ovarian and breast cancer, multiple sclerosis, and discovered the first genes for uterine fibroids, nausea and vomiting of pregnancy (NVP), and hyperemesis gravidarum (HG). Fejzo is a Clinical Professor at the University of Southern California, Chief Scientific Officer of The Morning Sickness and HG Clinic, Research Advisor of the HER Foundation, Board Member of the Foundation for Women’s Health, Member of the Women’s Health Network, and an advisor for NGM Bio. Fejzo is a 2024 Time Woman of the Year and Time 100 Health Honoree, received the National Organization of Women Victoria Mastrobuono Award in Women’s Health, Forbes 50-Over-50 award in Innovation, is a Falling Walls Breakthrough of the Year Finalist, and the inaugural BII & Science Translational Medicine Prize for Innovations in Women’s Health grand prize winner.

Publications

  • Whole-exome sequencing uncovers new variants in GDF15 associated with hyperemesis gravidarum. BJOG. 2022 10; 129(11):1845-1852.. View in PubMed
  • HyperEmesis Level Prediction (HELP Score) Identifies Patients with Indicators of Severe Disease: a Validation Study. Geburtshilfe Frauenheilkd. 2021 Jan; 81(1):90-98.. View in PubMed
  • Analysis in epithelial ovarian cancer identifies KANSL1 as a biomarker and target gene for immune response and HDAC inhibition. Gynecol Oncol. 2021 02; 160(2):539-546.. View in PubMed
  • A core outcome set for hyperemesis gravidarum studies is a small step in the right direction. BJOG. 2020 07; 127(8):993.. View in PubMed
  • Nausea and vomiting of pregnancy and hyperemesis gravidarum. Nat Rev Dis Primers. 2019 09 12; 5(1):62.. View in PubMed
  • Analysis of GDF15 and IGFBP7 in Hyperemesis Gravidarum Support Causality. Geburtshilfe Frauenheilkd. 2019 Apr; 79(4):382-388.. View in PubMed
  • Analysis of neurodevelopmental delay in children exposed in utero to hyperemesis gravidarum reveals increased reporting of autism spectrum disorder. Reprod Toxicol. 2019 03; 84:59-64.. View in PubMed
  • Evidence GDF15 Plays a Role in Familial and Recurrent Hyperemesis Gravidarum. Geburtshilfe Frauenheilkd. 2018 Sep; 78(9):866-870.. View in PubMed
  • Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum. Nat Commun. 2018 03 21; 9(1):1178.. View in PubMed
  • Critique of inaccurate reporting in Edlavitch article on “Publishing negative findings and the challenge of avoiding type II errors in studies of suspect teratogens: Example of a recent ondansetron publication”. Reprod Toxicol. 2018 01; 75:144-145.. View in PubMed

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