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Radha Kalluri, PhD

Associate Professor of Otolaryngology - Head & Neck Surgery and Biomedical Engineering

Division Chief of Research

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Phone +1 323 442 4820
Email [email protected]
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Overview

Dr. Radha Kalluri heads the Physiology of the Inner Ear Laboratory whose focus is to understand the physical and physiological mechanisms underlying sensory transduction in the inner ear, with the ultimate goal of understanding how disease and injury impair function. The lab. studies sensory transduction in the auditory and vestibular systems both at the cellular and system level using electrophysiology and biophysical modeling. Our work relies heavily on the interplay between quantitative analysis, theoretical modeling and experimental neuroscience.

https://keck.usc.edu/otolaryngology/

Research Funding

  • The role of ion channels in shaping the function of inner ear neurons
    NIH · R01DC015512 · Jul 1, 2017 – Nov 30, 2027 · Role: Principal Investigator
  • Biophysical properties and function of primary auditory neurons
    NIH · R03DC012652 · Mar 1, 2013 – Feb 28, 2017 · Role: Principal Investigator
  • Firing patterns in vestibular afferents
    NIH · F32DC009360 · Dec 1, 2007 – Nov 30, 2010 · Role: Principal Investigator

Publications

  • Gradients in the biophysical properties of neonatal auditory neurons align with synaptic contact position and the intensity coding map of inner hair cells. Elife. 2020 07 08; 9.. View in PubMed
  • Generation of inner ear hair cells by direct lineage conversion of primary somatic cells. Elife. 2020 06 30; 9.. View in PubMed
  • Enhanced Activation of HCN Channels Reduces Excitability and Spike-Timing Regularity in Maturing Vestibular Afferent Neurons. J Neurosci. 2019 04 10; 39(15):2860-2876.. View in PubMed
  • Towards a joint reflection-distortion otoacoustic emission profile: Results in normal and impaired ears. J Acoust Soc Am. 2017 08; 142(2):812.. View in PubMed
  • Spatial Gradients in the Size of Inner Hair Cell Ribbons Emerge Before the Onset of Hearing in Rats. J Assoc Res Otolaryngol. 2017 Jun; 18(3):399-413.. View in PubMed
  • A biophysical model examining the role of low-voltage-activated potassium currents in shaping the responses of vestibular ganglion neurons. J Neurophysiol. 2016 08 01; 116(2):503-21.. View in PubMed
  • Stimulus-frequency otoacoustic emissions in human newborns. J Acoust Soc Am. 2015 Jan; 137(1):EL78-84.. View in PubMed
  • Exploiting Dual Otoacoustic Emission Sources. AIP Conf Proc. 2015; 1703.. View in PubMed
  • Measuring stimulus-frequency otoacoustic emissions using swept tones. J Acoust Soc Am. 2013 Jul; 134(1):356-68.. View in PubMed
  • Deviations from Scaling Symmetry in the Apical Half of the Human Cochlea. AIP Conf Proc. 2011; 1403:483-488.. View in PubMed

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