Keck School Faculty

Rayudu Gopalakrishna, PhD
Rayudu Gopalakrishna, PhD
Associate Professor of Integrative Anatomical Sciences
Integrative Anatomical Sciences
BMT 306 A 1333 San Pablo Street Health Sciences Campus Los Angeles

Keck School of Medicine of USC: Outstanding Teaching Award (Year I med), 2014

Keck School of Medicine of USC: Outstanding Teaching Award (Year II med), 2014

Keck School of Medicine of USC: Outstanding Teaching Award (Year I med), 2011

Alpha Omega Alpha: Membership, 2010

Keck School of Medicine of USC: Outstanding Teaching Award (Year II med), 2008

Keck School of Medicine of USC: Master Teacher, 2008

Keck School of Medicine of USC: Outstanding Teaching Award (Year I med), 2006

Keck School of Medicine of USC: Outstanding teaching Award (year II med), 2004

Keck School of Medicine of USC: Outstanding Teaching Award (year I med), 2003

Keck School of Medicine of USC: Outstanding Teaching Award (year II med), 2000

Keck School of Medicine of USC: Outstanding Teaching Award (year II med)), 1996

Keck School of Medicine of USC: Excellence in Teaching Certificate, 1995

National Cancer Institute, NIH: FIRST Award, 1988-1993

Cell signaling associated with internalization of 67 kDa laminin receptor (67LR) by soluble laminin and its implication for protection against neurodegenerative diseases Neural Regen Res. 2019 Sep; 14(9):1513-1514. . View in PubMed

Redox regulation of protein kinase C by selenometabolites and selenoprotein thioredoxin reductase limits cancer prevention by selenium Free Radic Biol Med. 2018 Nov 01; 127:55-61. . View in PubMed

Redox regulation of protein kinase C by selenometabolites and selenoprotein thioredoxin reductase limits cancer prevention by selenium Free Radic Biol Med. 2018 May 22. . View in PubMed

Lowering side effects of NSAID usage in osteoarthritis: recent attempts at minimizing dosage Expert Opin Pharmacother. 2018 Feb; 19(2):93-102. . View in PubMed

Lowering side effects of NSAID usage in osteoarthritis: recent attempts at minimizing dosage Expert Opin Pharmacother. 2018 02; 19(2):93-102. . View in PubMed

Laminin-1 induces endocytosis of 67KDa laminin receptor and protects Neuroscreen-1 cells against death induced by serum withdrawal Biochem Biophys Res Commun. 2018 01 01; 495(1):230-237. . View in PubMed

Counteraction of Nogo-A and axonal growth inhibitors by green tea polyphenols and other natural products Neural Regen Res. 2016 Apr; 11(4):545-6. . View in PubMed

Imbalance in Protein Thiol Redox Regulation and Cancer-Preventive Efficacy of Selenium React Oxyg Species (Apex). 2016; 2(4):272-289. . View in PubMed

Polyphenols from green tea prevent antineuritogenic action of Nogo-A via 67-kDa laminin receptor and hydrogen peroxide J Neurochem. 2015 Jan; 132(1):70-84. . View in PubMed

Green tea catechins potentiate the neuritogenic action of brain-derived neurotrophic factor: role of 67-kDa laminin receptor and hydrogen peroxide Biochem Biophys Res Commun. 2014 Feb 28; 445(1):218-24. . View in PubMed

Methods for studying oxidative regulation of protein kinase C Methods Enzymol. 2013; 528:79-98. . View in PubMed

Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Ce J Biol Chem. 2012 Oct 05; 287(41):34694-708. . View in PubMed

Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species J Neurosci Res. 2010 Dec; 88(16):3644-55. . View in PubMed

Negation of the cancer-preventive actions of selenium by over-expression of protein kinase Cepsilon and selenoprotein thioredoxin reductase Carcinogenesis. 2009 Sep; 30(9):1553-61. . View in PubMed

Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells J Biol Chem. 2008 Dec 12; 283(50):34519-31. . View in PubMed

A direct redox regulation of protein kinase C isoenzymes mediates oxidant-induced neuritogenesis in PC12 cells J Biol Chem. 2008 May 23; 283(21):14430-44. . View in PubMed

The synthetic estrogen 4-estren-3 alpha,17 beta-diol (estren) induces estrogen-like neuroprotection Neurobiol Dis. 2005 Jun-Jul; 19(1-2):331-9. . View in PubMed

Estrogen activates protein kinase C in neurons: role in neuroprotection J Neurochem. 2003 Mar; 84(6):1340-8. . View in PubMed

Antioxidant regulation of protein kinase C in cancer prevention J Nutr. 2002 Dec; 132(12):3819S-3823S. . View in PubMed

Protein kinase C as a molecular target for cancer prevention by selenocompounds Nutr Cancer. 2001; 40(1):55-63. . View in PubMed

Protein kinase C signaling and oxidative stress Free Radic Biol Med. 2000 May 01; 28(9):1349-61. . View in PubMed

Tumor promoter benzoyl peroxide induces sulfhydryl oxidation in protein kinase C: its reversibility is related to the cellular resistance to peroxide-induced cytotoxicity Arch Biochem Biophys. 1999 Mar 15; 363(2):246-58. . View in PubMed

Differential distribution of protein phosphatase 2A in human breast carcinoma cell lines and its relation to estrogen receptor status Cancer Lett. 1999 Mar 01; 136(2):143-51. . View in PubMed

Role of protein kinase C in basal and hydrogen peroxide-stimulated NF-kappa B activation in the murine macrophage J774A1 cell line. Arch Biochem Biophys. 1998 Feb 01; 350(1):79-86. . View in PubMed

Selenocompounds induce a redox modulation of protein kinase C in the cell, compartmentally independent from cytosolic glutathione: its role in inhibition of tumor promotion Arch Biochem Biophys. 1997 Dec 01; 348(1):37-48. . View in PubMed

Cancer-preventive selenocompounds induce a specific redox modification of cysteine-rich regions in Ca(2+)-dependent isoenzymes of protein kinase C Arch Biochem Biophys. 1997 Dec 01; 348(1):25-36. . View in PubMed

Hypericin inhibits choroidal endothelial cell proliferation and cord formation in vitro Curr Eye Res. 1997 Oct; 16(10):967-72. . View in PubMed

Inhibition of cellular growth and induction of apoptosis in pituitary adenoma cell lines by the protein kinase C inhibitor hypericin: potential therapeutic application J Neurosurg. 1996 Aug; 85(2):329-34. . View in PubMed

Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells J Biol Chem. 1996 Jun 07; 271(23):13504-14. . View in PubMed

Enhancement of radiosensitivity in human malignant glioma cells by hypericin in vitro Clin Cancer Res. 1996 May; 2(5):843-6. . View in PubMed

Induction of intercellular adhesion molecule-1 by tumor necrosis factor-alpha through the 55-kDa receptor is dependent on protein kinase C in human retinal pigment epithelial cells Invest Ophthalmol Vis Sci. 1996 Mar; 37(4):597-606. . View in PubMed

Protein kinase C and growth regulation of pituitary adenomas Acta Neurochir Suppl. 1996; 65:22-6. . View in PubMed

Effect of linoleic acid hydroperoxide on endothelial cell calcium homeostasis and phospholipid hydrolysis Arch Biochem Biophys. 1995 Oct 20; 323(1):97-107. . View in PubMed

Modifications of cysteine-rich regions in protein kinase C induced by oxidant tumor promoters and enzyme-specific inhibitors Methods Enzymol. 1995; 252:132-46. . View in PubMed

Tobacco smoke tumor promoters, catechol and hydroquinone, induce oxidative regulation of protein kinase C and influence invasion and metastasis of lung carcinoma cells Proc Natl Acad Sci U S A. 1994 Dec 06; 91(25):12233-7. . View in PubMed

Transforming growth factor-beta regulates human retinal pigment epithelial cell phagocytosis by influencing a protein kinase C-dependent pathway Graefes Arch Clin Exp Ophthalmol. 1994 Nov; 232(11):695-701. . View in PubMed

Hypericin: a potential antiglioma therapy Neurosurgery. 1994 Oct; 35(4):705-9; discussion 709-10. . View in PubMed

Nitric oxide and nitric oxide-generating agents induce a reversible inactivation of protein kinase C activity and phorbol ester binding J Biol Chem. 1993 Dec 25; 268(36):27180-5. . View in PubMed

Multiwell filtration assay for rapid determination of protein phosphatase activity Anal Biochem. 1993 Jul; 212(1):296-9. . View in PubMed

Retinoids inhibit the oxidative modification of protein kinase C induced by oxidant tumor promoters Arch Biochem Biophys. 1993 Jan; 300(1):526-30. . View in PubMed

Nonphorbol tumor promoters okadaic acid and calyculin-A induce membrane translocation of protein kinase C Biochem Biophys Res Commun. 1992 Dec 15; 189(2):950-7. . View in PubMed

Irreversible oxidative inactivation of protein kinase C by photosensitive inhibitor calphostin C FEBS Lett. 1992 Dec 14; 314(2):149-54. . View in PubMed

Rapid filtration assays for protein kinase C activity and phorbol ester binding using multiwell plates with fitted filtration discs Anal Biochem. 1992 Oct; 206(1):24-35. . View in PubMed

Reversible oxidative activation and inactivation of protein kinase C by the mitogen/tumor promoter periodate Arch Biochem Biophys. 1991 Mar; 285(2):382-7. . View in PubMed

Powered by SC CTSI
Go to Top