Robinder G. Khemani, MD

Professor of Pediatrics (Clinical Scholar)

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Overview

Dr. Khemani is a Pediatric Intensive Care Physician and Clinical Researcher at the Children’s Hospital Los Angeles. His major area of research interest involves using observational data to answer important clinical questions in the realm of pediatric critical care. This includes but is not limited to the creation and validation of quality indicators and severity of illness scores to develop objective criteria for comparing pediatric intensive care unit (PICU) outcomes internationally. This work involves both disease specific markers for certain subgroups of PICU patients, or global ICU populations. These findings will help target specific areas for quality improvement, and help evaluate new interventions and treatment modalities.

He is also interested in pediatric mechanical ventilation, lung injury, and respiratory physiology, both translationally and at the bedside. He has specific interests in acute respiratory distress syndrome and upper airway obstruction: developing and validating minimally invasive pulmonary function techniques. Moreover, he uses his background in statistical modeling to examine the impact of different treatment regimens on cohorts of patients with specific respiratory disease such as upper airway obstruction, obstructive airways, hypoxemic respiratory failure, and acute lung injury.

Publications

  • Decision Assist During Mechanical Ventilation. Respir Care. 2026 02; 71(2):226-236.. View in PubMed
  • Post Extubation Noninvasive Respiratory Support for Pediatric ARDS. Pediatr Pulmonol. 2025 Nov; 60(11):e71375.. View in PubMed
  • Differentiating Lung From Chest Wall Mechanics Is Difficult Without Esophageal Manometry in Children With Acute Respiratory Distress Syndrome. Crit Care Med. 2025 Nov 01; 53(11):e2211-e2221.. View in PubMed
  • Contemporary Trends in Pediatric Extubation Failure and Noninvasive Respiratory Support Use. Chest. 2026 Jan; 169(1):106-114.. View in PubMed
  • Randomized Trial of Lung and Diaphragm Protective Ventilation in Children. NEJM Evid. 2025 Jun; 4(6):EVIDoa2400360.. View in PubMed
  • An overview of patient-ventilator asynchrony in children. Expert Rev Respir Med. 2025 May; 19(5):435-447.. View in PubMed
  • Phoenix Sepsis Criteria in Critically Ill Children: Retrospective Validation Using a United States Nine-Center Dataset, 2012-2018. Pediatr Crit Care Med. 2025 Feb 01; 26(2):e155-e165.. View in PubMed
  • Planning a Phased Guideline Implementation Strategy Across the Multicenter Ventilation Liberation for Kids (VentLib4Kids) Collaborative. Pediatr Crit Care Med. 2025 Mar 01; 26(3):e396-e407.. View in PubMed
  • Challenges in using the ROX index as a predictor of failure in high flow nasal cannula in infants with respiratory failure. Pediatr Pulmonol. 2025 Jan; 60(1):e27332.. View in PubMed
  • Phenotypes based on respiratory drive and effort to identify the risk factors when P0.1 fails to estimate ∆PES in ventilated children. Crit Care. 2024 10 04; 28(1):325.. View in PubMed