Srikar Chamala, PhD

Associate Professor of Clinical Pathology

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Overview

Srikar Chamala, PhD, is an Associate Professor of Clinical Pathology at the Keck School of Medicine of USC. He also serves as Director of the Center for Pathology Informatics and Data Science at Children’s Hospital Los Angeles. The major areas of research interest include clinical genome informatics, cancer disparity informatics, pathology informatics and data analytics, and translational bioinformatics.

Education and Training

  • University of Florida, Gainesville, FL, USA — PhD — 05/2014 — Bioinformatics / Comparative Genomics
  • University of Illinois, Urbana-Champaign, IL, USA — MS — 05/2008 — Bioinformatics
  • Brigham Young University, Provo, UT, USA — BS — 12/2006 — Bioinformatics

Publications

  • Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes. Genome Biol. 2021 01 21; 22(1):39.. View in PubMed
  • Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis. Diabetes. 2021 04; 70(4):932-943.. View in PubMed
  • Optimizing COVID-19 testing capabilities and clinical management using pathology informatics. JAMIA Open. 2020 Dec; 3(4):523-529.. View in PubMed
  • Informatics driven quality improvement in the modern histology lab. JAMIA Open. 2020 Dec; 3(4):530-535.. View in PubMed
  • Histological validation of a type 1 diabetes clinical diagnostic model for classification of diabetes. Diabet Med. 2020 12; 37(12):2160-2168.. View in PubMed
  • Disparities in Pancreatic Ductal Adenocarcinoma-The Significance of Hispanic Ethnicity, Subgroup Analysis, and Treatment Facility on Clinical Outcomes. Cancer Med. 2020 06; 9(12):4069-4082.. View in PubMed
  • Informatics Training for Pathology Practice and Research in the Digital Era. Acad Pathol. 2020 Jan-Dec; 7:2374289520911179.. View in PubMed
  • The avocado genome informs deep angiosperm phylogeny, highlights introgressive hybridization, and reveals pathogen-influenced gene space adaptation. Proc Natl Acad Sci U S A. 2019 08 20; 116(34):17081-17089.. View in PubMed
  • Endometrial Thickness as Measured by Transvaginal Ultrasound and the Corresponding Histopathologic Diagnosis in Women With Postmenopausal Bleeding. Int J Gynecol Pathol. 2017 Jul; 36(4):348-355.. View in PubMed
  • Deep reticulation and incomplete lineage sorting obscure the diploid phylogeny of rain-lilies and allies (Amaryllidaceae tribe Hippeastreae). Mol Phylogenet Evol. 2017 06; 111:231-247.. View in PubMed