Stan Louie, PharmD

Professor Of Clinical Pharmacy

Image of Stan Louie, PharmD
Is this your profile? Click to edit

Overview

Dr. Louie is a translational pharmacologist with expertise in advancing hit candidates through preclinical development and into clinical evaluation. His drug discovery strategies is to use metabolomics/lipidomics to identify drug targets. His team has developed four therapeutic modality from benchtop to clinical evaluation. His area of focus include inflammation and development of drug that promote regenerations.

Awards

  • March of Dimes Research Fellowship, 1979
     – 1982
  • Rho Chi Honor Society, 1985
  • Paper of the Year Award, 1997
  • California Society of Health System Pharmacist: Fellow, 1998
  • American Society of Health System Pharmacists: Fellow, 2000

Research Funding

  • Drug Development for Alzheimer's neuroinflammation
    NIH · U01AG094622 · Aug 1, 2025 – Jul 31, 2030 · Role: Co-Principal Investigator
  • NorLeu3Angiotensin (1-7) Promotes Non-Fibrotic Healing in Ocular Globe Injury Models
    Department of Defense · Sep 1, 2021 – Aug 31, 2024
  • Molecular Mechanism of Drug Resistance in Obese Leukemic
    National Cancer Institute · Jul 1, 2017 – Jun 30, 2022

Research Keywords

  • Inflammation, RAS, Specialize Lipid Mediators

Publications

  • Proximal tubule ACE2 mediates early responses to hypertension by regulating intrarenal RAS and sodium homeostasis. JCI Insight. 2026 Sep 22; 11(18).. View in PubMed
  • Brain pro-resolving-to-pro-inflammatory lipids and cPLA2 activation associations with late-life cognitive trajectories. EBioMedicine. 2026 Sep; 131:106421.. View in PubMed
  • CNS target engagement of high-dose DHA supplementation in older adults at risk for dementia: a randomised, double-blind, placebo-controlled trial. EBioMedicine. 2026 Jul; 129:106316.. View in PubMed
  • The effect of long-term oral tamoxifen and metabolism in the mouse ovary. Reprod Toxicol. 2026 Aug; 143:109264.. View in PubMed
  • Administration of Topical NorLeu3Angiotensin(1-7) Minimizes Fibrotic Corneal Healing in Stellate Wound: A 28-Day Study. Int J Mol Sci. 2026 Apr 16; 27(8).. View in PubMed
  • A perspective: PLA2G4A as drug target for vascular inflammation in Alzheimer’s disease. Alzheimers Dement. 2026 Apr; 22(4):e71320.. View in PubMed
  • Long-term tamoxifen impacts the ovary but not preimplantation embryo development†. Biol Reprod. 2026 03 16; 114(3):1115-1126.. View in PubMed
  • Evidence for cPLA2 activation in Alzheimer’s disease synaptic pathology. Acta Neuropathol Commun. 2026 02 12; 14(1).. View in PubMed
  • Development of potent, selective cPLA2 inhibitors for targeting neuroinflammation in Alzheimer’s disease and other neurodegenerative disorders. NPJ Drug Discov. 2026; 3(1):2.. View in PubMed
  • Telmisartan reduces systemic inflammation and alters the renin-angiotensin system in mild COVID-19. Sci Rep. 2025 Dec 03; 16(1):720.. View in PubMed