Stan Louie, PharmD

Professor Of Clinical Pharmacy

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Overview

Dr. Louie is a translational pharmacologist with expertise in advancing hit candidates through preclinical development and into clinical evaluation. His drug discovery strategies is to use metabolomics/lipidomics to identify drug targets. His team has developed four therapeutic modality from benchtop to clinical evaluation. His area of focus include inflammation and development of drug that promote regenerations.

Awards

  • March of Dimes Research Fellowship, 1979
     – 1982
  • Rho Chi Honor Society, 1985
  • Paper of the Year Award, 1997
  • California Society of Health System Pharmacist: Fellow, 1998
  • American Society of Health System Pharmacists: Fellow, 2000

Research Funding

  • Drug Development for Alzheimer's neuroinflammation
    NIH · U01AG094622 · Aug 1, 2025 – Jul 31, 2030 · Role: Co-Principal Investigator
  • NorLeu3Angiotensin (1-7) Promotes Non-Fibrotic Healing in Ocular Globe Injury Models
    Department of Defense · Sep 1, 2021 – Aug 31, 2024
  • Molecular Mechanism of Drug Resistance in Obese Leukemic
    National Cancer Institute · Jul 1, 2017 – Jun 30, 2022

Research Keywords

  • Inflammation, RAS, Specialize Lipid Mediators

Publications

  • Adipocytes Impair Mitoxantrone Cytotoxicity Against Acute Lymphoblastic Leukemia. EJHaem. 2025 Oct; 6(5):e70140.. View in PubMed
  • Evidence for cPLA2 activation in Alzheimer’s Disease Synaptic Pathology. bioRxiv. 2025 Apr 01.. View in PubMed
  • Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD. Mol Neurodegener. 2025 Feb 04; 20(1):15.. View in PubMed
  • Transcorneal electrical stimulation restores DNA methylation changes in retinal degeneration. Front Mol Neurosci. 2024; 17:1484964.. View in PubMed
  • Botulinum Toxin Application for Treatment of Graft Vasospasm: A Reverse Translational Study. medRxiv. 2024 Nov 13.. View in PubMed
  • Nicotinamide Riboside and CD38: Covalent Inhibition and Live-Cell Labeling. JACS Au. 2024 Nov 25; 4(11):4345-4360.. View in PubMed
  • Characterization of Induced Current Density During Transcorneal Electrical Stimulation to Promote Neuroprotection in the Degenerating Retina. IEEE Trans Biomed Eng. 2024 11; 71(11):3221-3231.. View in PubMed
  • Adipocyte maturation impacts daunorubicin disposition and metabolism. Eur J Clin Invest. 2024 Dec; 54(12):e14307.. View in PubMed
  • Immunonutrition with Omega-3 Fatty Acid Supplementation in Severe TBI: Retrospective Analysis of Patient Characteristics and Outcomes. Neurotrauma Rep. 2024; 5(1):574-583.. View in PubMed
  • Effects of age on lacrimal gland bioactive lipids. Ocul Surf. 2024 07; 33:64-73.. View in PubMed