William Stohl, MD, PhD

Professor of Medicine

Chief, Division of Rheumatology

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Overview

Dr. Stohl’s research focus is on systemic lupus erythematosus (pathogenesis, natural course of disease, treatment, animal models, immunologic disturbances, novel therapeutics); rheumatoid arthritis (pathogenesis, natural course of disease, treatment, animal models, immunologic disturbances, novel therapeutics); Sjogren’s syndrome (biomarkers, novel therapeutics); and B cells (basic biology, role in autoimmune diseases, development of targeted therapies).

Dr. Stohl received his M.D. (1977) and his Ph.D. (1979) from the University Pennsylvania.

Awards

  • University of Pennsylvania School of Medicine: Upjohn Award, 1979
  • Arthritis Foundation Southern California Chapter: James R. Klinenberg, M.D. Award, 2003

Research Funding

  • The vital role of BAFF in the development of SLE
    NIH · R01AR050193 · May 16, 2006 – Aug 31, 2012 · Role: Principal Investigator
  • T CELL CYTOLYTIC ACTIVITY IN SLE
    NIH · R01AR041006 · Aug 12, 1993 – Jun 30, 2002 · Role: Principal Investigator
  • POLYMORPHISM WITHIN T4/LEU3 AND SLE
    NIH · R23AR036527 · Jan 1, 1986 – Jun 30, 1989 · Role: Principal Investigator

Publications

  • Industry Payments to United States Rheumatologist-Authors of Publications in High-Impact Rheumatology Journals. ACR Open Rheumatol. 2023 Nov; 5(11):609-618.. View in PubMed
  • Impaired dynamic X-chromosome inactivation maintenance in T cells is a feature of spontaneous murine SLE that is exacerbated in female-biased models. J Autoimmun. 2023 09; 139:103084.. View in PubMed
  • Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms. Commun Biol. 2023 03 20; 6(1):295.. View in PubMed
  • Belimumab for the treatment of pediatric patients with lupus nephritis. Expert Opin Biol Ther. 2023 03; 23(3):243-251.. View in PubMed
  • Maternal and cord blood BAFF and APRIL levels during pregnancy. Am J Reprod Immunol. 2023 03; 89(3):e13654.. View in PubMed
  • B Cell and T Cell Dissimilarities in BAFF-Deficient versus BR3-Deficient C57BL/6 Mice. J Immunol. 2022 12 01; 209(11):2133-2140.. View in PubMed
  • Impact of Belimumab on Organ Damage in Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2022 11; 74(11):1822-1828.. View in PubMed
  • Preferential Expansion of Foxp3+ T Regulatory Cells in CTLA-4-Deficient and CTLA-4-Haploinsufficient C57BL/6 Mice. Immunohorizons. 2022 07 25; 6(7):507-514.. View in PubMed
  • Reductions in circulating B cell subsets and immunoglobulin G levels with long-term belimumab treatment in patients with SLE. Lupus Sci Med. 2022 02; 9(1).. View in PubMed
  • First-trimester serum BAFF:sFlt-1 ratio as a candidate early biomarker of spontaneous abortion. Am J Reprod Immunol. 2021 10; 86(4):e13428.. View in PubMed