Woojin An, PhD

Dr. An is a Professor of Cancer Biology at the Keck School of Medicine of USC. His research program is focused on using multi-disciplinary biochemical and cellular approaches to understand fundamental concepts and mechanisms of action of epigenetic histone remodeling in various cellular events. Specifically, his laboratory employs multiple assay systems and methods to dissect molecular details of how histone modification, histone variant exchange, and histone tail proteolysis regulate chromatin structure and control gene expression processes. Current projects involve genome-wide location analysis and functional characterization of histone marks and downstream effectors that are crucial for epigenetic regulation of cell growth, differentiation, and transformation. Dr. An received his Ph.D. in Biochemistry and Biophysics in 1998 from the Oregon State University and did his postdoctoral training at the Rockefeller University. He began his career on the faculty at USC in 2004.

• Epigenetic Regulation of Osteoclastogenic Gene Expression: Factors, Targets, and Mechanisms
  NIH · R01AR073233 · Aug 1, 2019 – Nov 30, 2024 · Role: Principal Investigator
• Role of histone kinase VprBP in gene silencing: mechanisms, targets, and regulation
  NIH · R01CA201561 · Jul 15, 2016 – Jun 30, 2021 · Role: Principal Investigator
• ROLE OF HISTONE H4 N-TERMINAL TAIL IN TRANSCRIPTION REGULATION
  NIH · R01GM084209 · Aug 1, 2008 – Jul 31, 2014 · Role: Principal Investigator

• Farnham, Peggy
• Rice, Judd
• Lenz, Heinz-Josef
• Liang, Gangning
• Dou, Yali
• Rhie, Suhn