Brian P. Lee, MD

Associate Professor of Clinical Medicine

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Overview

Dr. Lee is a transplant hepatologist who cares for patients with advanced liver disease and those undergoing liver transplantation. He leads ACCELERATE, an NIH-funded national research consortium, and his research program focuses on improving health for patients with alcohol use, metabolic dysfunction, and liver disease through: 1) early transplant with alcohol; 2) the overlap of alcohol and metabolic liver disease; 3) public policy and advocacy; and 4) novel therapies and translational science. He is lead author of studies in The Lancet, JAMA Internal Medicine, Annals of Internal Medicine, Gastroenterology, Journal of Hepatology, and his work has featured in New York Times, Wall Street Journal, NPR, CNN, the New Yorker, and NBC Nightly News. He has led advocacy initiatives that changed national and statewide transplant and insurance policies to improve healthcare access, and his research has been incorporated into practice guidelines across North America, Europe, Latin America, and Asia. He is first author of international expert task force consensus guidelines for clinical trial design in alcohol use and liver disease. He serves currently as Associate Editor for Hepatology, and has served as an Associate Editor for Journal of Hepatology Reports. He serves as a standing Voting Member of the FDA Gastrointestinal Drugs Advisory Committee and as a Voting Member of the FDA Pharmacy Compounding Advisory Committee.

Awards

  • European Association for the Study of the Liver: Young Investigator Bursary Award, 2019
  • American Association for the Study of Liver Diseases: Clinical/Translational Early Career Investigator Award, 2018
  • American Society of Transplantation: Young Investigator Award, 2018
  • International Liver Transplantation Society: Young Investigator Award, 2017
  • Johns Hopkins Hospital: Resident Teaching Award, 2016
  • Summa Cum Laude, 2013
  • Alpha Omega Alpha (AOA), 2013
  • Phi Beta Kappa, 2010

Education and Training

  • Johns Hopkins Osler Program — 2016 — Internal Medicine
  • UCSF — 2019 — Gastroenterology
  • UCSF — 2020 — Transplant Hepatology

Research Funding

  • American Consortium of Early Liver Transplantation-Prospective Alcohol-associated liver disease Cohort Evaluation (ACCELERATE-PACE)
    NIH · R01AA030960 · Aug 1, 2023 – Jul 31, 2030
  • Estimating the Contribution of Alcohol and Metabolic Risk to Liver Disease Progression to Inform Personalized Interventions
    NIH · K23AA029752 · Jul 15, 2022 – Jun 30, 2026 · Role: Principal Investigator
  • Estimating the Contribution of Alcohol and Metabolic Risk to Liver Disease Progression to Inform Personalized Interventions
    NIH · K23AA029752 · Jul 1, 2022 – Jun 30, 2026

Media

Publications

  • Artificial intelligence to identify harmful alcohol use after early liver transplant for alcohol-associated hepatitis. Am J Transplant. 2022 07; 22(7):1834-1841.. View in PubMed
  • Duration and cost-effectiveness of hepatocellular carcinoma surveillance in hepatitis C patients after viral eradication. J Hepatol. 2022 07; 77(1):55-62.. View in PubMed
  • Subclinical hepatic fibrosis is associated with coronary microvascular dysfunction by myocardial perfusion reserve index: a retrospective cohort study. Int J Cardiovasc Imaging. 2022 Jul; 38(7):1579-1586.. View in PubMed
  • Discordance in categorization of acute-on-chronic liver failure in the United Network for Organ Sharing database. J Hepatol. 2022 05; 76(5):1122-1126.. View in PubMed
  • Medicaid expansion and variability in mortality in the USA: a national, observational cohort study. Lancet Public Health. 2022 01; 7(1):e48-e55.. View in PubMed
  • Changes and mediators of survival disparity among Black liver transplant recipients in the United States. Am J Transplant. 2021 12; 21(12):3883-3893.. View in PubMed
  • Ultrasonic Percutaneous Tenotomy for Recalcitrant Lateral Elbow Tendinopathy: Clinical and Sonographic Results at 90 Months. Am J Sports Med. 2021 06; 49(7):1854-1860.. View in PubMed
  • Retail Alcohol and Tobacco Sales During COVID-19. Ann Intern Med. 2021 07; 174(7):1027-1029.. View in PubMed
  • Excess Mortality After Liver Transplantation in Young Women With Alcohol-Associated Liver Disease. Am J Gastroenterol. 2021 03 01; 116(3):551-559.. View in PubMed
  • Bariatric surgery and the risk of alcohol-related cirrhosis and alcohol misuse. Liver Int. 2021 05; 41(5):1012-1019.. View in PubMed