Keck School Faculty

Subcortical brain alterations in carriers of genomic copy number variants medRxiv. 2023 Feb 22. . View in PubMed

Volume of subcortical brain regions in social anxiety disorder: mega-analytic results from 37 samples in the ENIGMA-Anxiety Working Group Mol Psychiatry. 2023 Jan 19. . View in PubMed

Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q112 deletion syndrome: A review of ENIGMA findings. Psychiatry Clin Neurosci. 2022 May; 76(5):140-161. . View in PubMed

Genomic and neuroimaging approaches to bipolar disorder BJPsych Open. 2022 Feb 01; 8(2):e36. . View in PubMed

Shape analysis of subcortical structures in obsessive-compulsive disorder and the relationship with comorbid anxiety, depression, and medication use: A meta-analysis by the OCD Brain Imaging Consortium Brain Behav. 2022 10; 12(10):e2755. . View in PubMed

Longitudinal trajectories of cortical development in 22q112 copy number variants and typically developing controls. Mol Psychiatry. 2022 10; 27(10):4181-4190. . View in PubMed

Remodeling of the Cortical Structural Connectome in Posttraumatic Stress Disorder: Results From the ENIGMA-PGC Posttraumatic Stress Disorder Consortium Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 09; 7(9):935-948. . View in PubMed

Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs Hum Brain Mapp. 2022 01; 43(1):300-328. . View in PubMed

Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90? years. Hum Brain Mapp. 2022 01; 43(1):431-451.. View in PubMed

Neuroinformatics. 2022 01; 20(1):261-275. . View in PubMed

Subcortical shape alterations in major depressive disorder: Findings from the ENIGMA major depressive disorder working group Hum Brain Mapp. 2022 01; 43(1):341-351. . View in PubMed

ENIGMA-DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross-diagnostic psychiatric research Hum Brain Mapp. 2022 01; 43(1):194-206. . View in PubMed

What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group Hum Brain Mapp. 2022 01; 43(1):56-82. . View in PubMed

Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder Hum Brain Mapp. 2022 01; 43(1):414-430. . View in PubMed

Greater male than female variability in regional brain structure across the lifespan Hum Brain Mapp. 2022 01; 43(1):470-499. . View in PubMed

In vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics through Meta-Analysis Bipolar Disorder Working Group Hum Brain Mapp. 2022 01; 43(1):385-398. . View in PubMed

Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90? years. Hum Brain Mapp. 2022 01; 43(1):452-469.. View in PubMed

A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium Hum Brain Mapp. 2022 01; 43(1):352-372. . View in PubMed

Virtual Ontogeny of Cortical Growth Preceding Mental Illness Biol Psychiatry. 2022 08 15; 92(4):299-313. . View in PubMed

Multiscale neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology Commun Biol. 2022 09 27; 5(1):1024. . View in PubMed

Site effects how-to and when: An overview of retrospective techniques to accommodate site effects in multi-site neuroimaging analyses Front Neurol. 2022; 13:923988. . View in PubMed

A comparison of methods to harmonize cortical thickness measurements across scanners and sites Neuroimage. 2022 11 01; 261:119509. . View in PubMed

RORA rs8042149 polymorphism moderates the association between PTSD symptom severity and transverse temporal gyrus thickness in Han Chinese adults who lost their only child J Affect Disord. 2022 10 01; 314:318-324. . View in PubMed

Local molecular and global connectomic contributions to cross-disorder cortical abnormalities Nat Commun. 2022 08 10; 13(1):4682. . View in PubMed

Harmonization of multi-scanner in vivo magnetic resonance spectroscopy: ENIGMA consortium task group considerations Front Neurol. 2022; 13:1045678. . View in PubMed

Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders Nat Commun. 2022 11 11; 13(1):6851. . View in PubMed

Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group Biol Psychiatry. 2022 03 15; 91(6):582-592. . View in PubMed

Association between body mass index and subcortical brain volumes in bipolar disorders-ENIGMA study in 2735 individuals Mol Psychiatry. 2021 11; 26(11):6806-6819. . View in PubMed

Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group Mol Psychiatry. 2021 09; 26(9):5124-5139. . View in PubMed

Structural and functional brain alterations revealed by neuroimaging in CNV carriers Curr Opin Genet Dev. 2021 06; 68:88-98. . View in PubMed

Structural brain imaging studies offer clues about the effects of the shared genetic etiology among neuropsychiatric disorders Mol Psychiatry. 2021 06; 26(6):2101-2110. . View in PubMed

Association of Immunosuppression and Viral Load With Subcortical Brain Volume in an International Sample of People Living With HIV JAMA Netw Open. 2021 01 04; 4(1):e2031190. . View in PubMed

Prioritizing Genetic Contributors to Cortical Alterations in 22q112 Deletion Syndrome Using Imaging Transcriptomics. Cereb Cortex. 2021 06 10; 31(7):3285-3298. . View in PubMed

1q211 distal copy number variants are associated with cerebral and cognitive alterations in humans. Transl Psychiatry. 2021 03 22; 11(1):182. . View in PubMed

Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders JAMA Psychiatry. 2021 Jan 01; 78(1):47-63. . View in PubMed

Altered white matter microstructure in 22q112 deletion syndrome: a multisite diffusion tensor imaging study. Mol Psychiatry. 2020 11; 25(11):2818-2831. . View in PubMed

Subcortical surface morphometry in substance dependence: An ENIGMA addiction working group study Addict Biol. 2020 11; 25(6):e12830. . View in PubMed

Using structural MRI to identify bipolar disorders - 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group Mol Psychiatry. 2020 09; 25(9):2130-2143. . View in PubMed

Large-scale mapping of cortical alterations in 22q112 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size. Mol Psychiatry. 2020 08; 25(8):1822-1834. . View in PubMed

The genetic architecture of the human cerebral cortex Science. 2020 03 20; 367(6484). . View in PubMed

Brain structural correlates of insomnia severity in 1053 individuals with major depressive disorder: results from the ENIGMA MDD Working Group Transl Psychiatry. 2020 12 08; 10(1):425. . View in PubMed

Association of Copy Number Variation of the 15q112 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition. JAMA Psychiatry. 2020 04 01; 77(4):420-430. . View in PubMed

Mapping Subcortical Brain Alterations in 22q112 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness. Am J Psychiatry. 2020 07 01; 177(7):589-600. . View in PubMed

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries Transl Psychiatry. 2020 03 20; 10(1):100. . View in PubMed

Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals Neuropsychopharmacology. 2019 12; 44(13):2285-2293. . View in PubMed

Genetic architecture of subcortical brain structures in 38,851 individuals Nat Genet. 2019 11; 51(11):1624-1636. . View in PubMed

Progressive brain atrophy in chronically infected and treated HIV+ individuals J Neurovirol. 2019 06; 25(3):342-353. . View in PubMed

Striatal morphology and neurocognitive dysfunction in Huntington disease: The IMAGE-HD study Psychiatry Res Neuroimaging. 2019 09 30; 291:1-8. . View in PubMed

Altered Cortical Brain Structure and Increased Risk for Disease Seen Decades After Perinatal Exposure to Maternal Smoking: A Study of 9000 Adults in the UK Biobank Cereb Cortex. 2019 12 17; 29(12):5217-5233. . View in PubMed

The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder Biol Psychiatry. 2019 10 01; 86(7):545-556. . View in PubMed

Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group Mol Psychiatry. 2018 04; 23(4):932-942. . View in PubMed

Machine Learning for Large-Scale Quality Control of 3D Shape Models in Neuroimaging Mach Learn Med Imaging. 2017 Sep; 10541:371-378. . View in PubMed

Novel genetic loci associated with hippocampal volume Nat Commun. 2017 01 18; 8:13624. . View in PubMed

Generalized reduced rank latent factor regression for high dimensional tensor fields, and neuroimaging-genetic applications Neuroimage. 2017 01 01; 144(Pt A):35-57. . View in PubMed

Mapping 22q112 Gene Dosage Effects on Brain Morphometry. J Neurosci. 2017 06 28; 37(26):6183-6199. . View in PubMed

Novel genetic loci underlying human intracranial volume identified through genome-wide association Nat Neurosci. 2016 12; 19(12):1569-1582. . View in PubMed

MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trials Neurobiol Aging. 2016 Jan; 37:26-37. . View in PubMed

A Model For Teaching Advanced Neuroscience Methods: A Student-Run Seminar to Increase Practical Understanding and Confidence J Undergrad Neurosci Educ. 2016; 15(1):A5-A10. . View in PubMed

Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2 Alzheimers Dement. 2015 Jul; 11(7):740-56. . View in PubMed

Common genetic variants influence human subcortical brain structures Nature. 2015 Apr 09; 520(7546):224-9. . View in PubMed

Medial Demons Registration Localizes The Degree of Genetic Influence Over Subcortical Shape Variability: An N= 1480 Meta-Analysis Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:1402-1406. . View in PubMed

Does MRI scan acceleration affect power to track brain change? Neurobiol Aging. 2015 Jan; 36 Suppl 1:S167-77.. View in PubMed

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data Brain Imaging Behav. 2014 Jun; 8(2):153-82. . View in PubMed

Unbiased tensor-based morphometry: improved robustness and sample size estimates for Alzheimer's disease clinical trials Neuroimage. 2013 Feb 01; 66:648-61. . View in PubMed

MRI signatures of brain macrostructural atrophy and microstructural degradation in frontotemporal lobar degeneration subtypes J Alzheimers Dis. 2013; 33(2):431-44. . View in PubMed

Differential putaminal morphology in Huntington's disease, frontotemporal dementia and Alzheimer's disease Aust N Z J Psychiatry. 2012 Dec; 46(12):1145-58. . View in PubMed

Patterns of altered cortical perfusion and diminished subcortical integrity in posttraumatic stress disorder: an MRI study Neuroimage. 2011 Jan; 54 Suppl 1:S62-8. . View in PubMed

Joint assessment of structural, perfusion, and diffusion MRI in Alzheimer's disease and frontotemporal dementia Int J Alzheimers Dis. 2011; 2011:546871. . View in PubMed

Training programme for rural midwives in Mozambique Trop Doct. 1985 Jul; 15(3):146-7. . View in PubMed