Mark S. Borchert, MD

Clinical Professor of Ophthalmology (Part-Time)

Image of Mark S. Borchert, MD
Is this your profile? Click to edit

Overview

Mark S. Borchert, MD earned a medical degree from Baylor College of Medicine. He completed his residency in the Department of Ophthalmology, University of Southern California, and a fellowship in neuro-ophthalmology at the Massachusetts Eye & Ear Infirmary, Harvard University. Dr. Borchert is the Director of Eye Birth Defects, leading the world’s largest study into optic nerve hypoplasia. Dr. Borchert, who has been listed in “Best Doctors in America,” also has received honors from the Pan American Association of Ophthalmology, the American Academy of Ophthalmology, and Society of Heed Fellows, as well as several teaching awards from the Keck School of Medicine. His research on the development of the retina and optic nerve in rats was part of an experiment on the NASA space shuttle.

Borchert investigates the development of the optic nerve and its retinotopic connections in the tectum (part of the midbrain) and thalamus (part of the forebrain). He is interested in the role that inaccurate or inadequate development of these connections plays in the pathogenesis of optic nerve hypoplasia, the leading cause of blindness in infants in the United states and Europe. His research focus also includes developing diagnostic tools using spectroscopic methods in the measurement of glucose levels in the eye.

Awards

  • Keck School of Medicine of USC: Resident Teaching Award, 1991
     – 1994
  • Keck School of Medicine of USC: Senior Resident Teaching Award, 1994
  • Keck School of Medicine of USC: Resident Teaching Award, 1996
  • Keck School of Medicine of USC: Resident Teaching Award, 1999
  • Keck School of Medicine of USC: Resident Teaching Award, 2001
  • American Academy of Ophthalmology: Achievement Award, 2002
  • America’s Top Doctors, 2006
     – 2009
  • Best Doctors in America Award, 2006
  • Pasadena Magazine Top Doctors Award, 2008
  • LA Magazine Best Doctors in Southern California, 2009
  • Best Doctors in America Award, 2009
  • LA Magazine: Super Doctors Award, 2010
  • Pasadena Magazine Top Doctors Award, 2010
  • Pasadena Magazine Top Doctors Award, 2013
     – 2014

Education and Training

  • Baylor College of Medicine — MD — 1983
  • USC Roski Eye Institute — Ophthalmology Residency — 1987
  • Massachusetts Eye & Ear Infirmary — Neuro-Ophthalmology Fellowship — 1988

Publications

  • Utility of In Vitro Mutagenesis of RPE65 Protein for Verification of Mutational Pathogenicity Before Gene Therapy. JAMA Ophthalmol. 2019 12 01; 137(12):1381-1388.. View in PubMed
  • Papilledema Treated by Cranial Expansion in a 5-Year-Old Boy with Camurati-Engelmann Syndrome. Ophthalmology. 2019 11; 126(11):1579.. View in PubMed
  • Factors Associated With Lack of Vision Improvement in Children With Cortical Visual Impairment. J Neuroophthalmol. 2018 12; 38(4):429-433.. View in PubMed
  • Decreased severity of age-related macular degeneration in amblyopic eyes. Br J Ophthalmol. 2018 11; 102(11):1575-1578.. View in PubMed
  • Pediatric Optic Neuritis: What Is New. J Neuroophthalmol. 2017 09; 37.. View in PubMed
  • Brain Malformations Do Not Predict Hypopituitarism in Young Children with Optic Nerve Hypoplasia. Horm Res Paediatr. 2017; 88(3-4):251-257.. View in PubMed
  • Predictive value of N95 waveforms of pattern electroretinograms (PERGs) in children with optic nerve hypoplasia (ONH). Doc Ophthalmol. 2017 10; 135(2):97-106.. View in PubMed
  • The Optic Nerve Hypoplasia Spectrum: Review of the Literature and Clinical Guidelines. Adv Pediatr. 2016 08; 63(1):127-46.. View in PubMed
  • Strabismus in patients with cortical visual impairment: outcomes of surgery and observations of spontaneous resolution. J AAPOS. 2016 Apr; 20(2):121-5.. View in PubMed
  • An evaluation of the safety and efficacy of bimatoprost for eyelash growth in pediatric subjects. Clin Ophthalmol. 2016; 10:419-29.. View in PubMed