Mark S. Borchert, MD

Clinical Professor of Ophthalmology (Part-Time)

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Overview

Mark S. Borchert, MD earned a medical degree from Baylor College of Medicine. He completed his residency in the Department of Ophthalmology, University of Southern California, and a fellowship in neuro-ophthalmology at the Massachusetts Eye & Ear Infirmary, Harvard University. Dr. Borchert is the Director of Eye Birth Defects, leading the world’s largest study into optic nerve hypoplasia. Dr. Borchert, who has been listed in “Best Doctors in America,” also has received honors from the Pan American Association of Ophthalmology, the American Academy of Ophthalmology, and Society of Heed Fellows, as well as several teaching awards from the Keck School of Medicine. His research on the development of the retina and optic nerve in rats was part of an experiment on the NASA space shuttle.

Borchert investigates the development of the optic nerve and its retinotopic connections in the tectum (part of the midbrain) and thalamus (part of the forebrain). He is interested in the role that inaccurate or inadequate development of these connections plays in the pathogenesis of optic nerve hypoplasia, the leading cause of blindness in infants in the United states and Europe. His research focus also includes developing diagnostic tools using spectroscopic methods in the measurement of glucose levels in the eye.

Awards

  • Keck School of Medicine of USC: Resident Teaching Award, 1991
     – 1994
  • Keck School of Medicine of USC: Senior Resident Teaching Award, 1994
  • Keck School of Medicine of USC: Resident Teaching Award, 1996
  • Keck School of Medicine of USC: Resident Teaching Award, 1999
  • Keck School of Medicine of USC: Resident Teaching Award, 2001
  • American Academy of Ophthalmology: Achievement Award, 2002
  • America’s Top Doctors, 2006
     – 2009
  • Best Doctors in America Award, 2006
  • Pasadena Magazine Top Doctors Award, 2008
  • LA Magazine Best Doctors in Southern California, 2009
  • Best Doctors in America Award, 2009
  • LA Magazine: Super Doctors Award, 2010
  • Pasadena Magazine Top Doctors Award, 2010
  • Pasadena Magazine Top Doctors Award, 2013
     – 2014

Education and Training

  • Baylor College of Medicine — MD — 1983
  • USC Roski Eye Institute — Ophthalmology Residency — 1987
  • Massachusetts Eye & Ear Infirmary — Neuro-Ophthalmology Fellowship — 1988

Publications

  • Prevalence of amblyopia or strabismus in asian and non-Hispanic white preschool children: multi-ethnic pediatric eye disease study. Ophthalmology. 2013 Oct; 120(10):2117-24.. View in PubMed
  • Prevalence and causes of visual impairment in Asian and non-Hispanic white preschool children: Multi-ethnic Pediatric Eye Disease Study. Ophthalmology. 2013 Jun; 120(6):1220-6.. View in PubMed
  • Optic nerve hypoplasia syndrome: a review of the epidemiology and clinical associations. Curr Treat Options Neurol. 2013 Feb; 15(1):78-89.. View in PubMed
  • Newborn thyroid-stimulating hormone in children with optic nerve hypoplasia: associations with hypothyroidism and vision. J AAPOS. 2012 Oct; 16(5):418-23.. View in PubMed
  • ATOH7 mutations cause autosomal recessive persistent hyperplasia of the primary vitreous. Hum Mol Genet. 2012 Aug 15; 21(16):3681-94.. View in PubMed
  • Serum prolactin concentrations in relation to hypopituitarism and obesity in children with optic nerve hypoplasia. Horm Res Paediatr. 2012; 77(5):277-80.. View in PubMed
  • Reappraisal of the optic nerve hypoplasia syndrome. J Neuroophthalmol. 2012 Mar; 32(1):58-67.. View in PubMed
  • Presenting features and long-term effects of growth hormone treatment of children with optic nerve hypoplasia/septo-optic dysplasia. Int J Pediatr Endocrinol. 2011 Nov 15; 2011(1):17.. View in PubMed
  • Risk factors for decreased visual acuity in preschool children: the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies. Ophthalmology. 2011 Nov; 118(11):2262-73.. View in PubMed
  • Risk factors for astigmatism in preschool children: the multi-ethnic pediatric eye disease and Baltimore pediatric eye disease studies. Ophthalmology. 2011 Oct; 118(10):1974-81.. View in PubMed