Ray Matthews, MD

Professor of Clinical Medicine

Director of Interventional Cardiology and Catheterization Laboratories

Director, CVI Outreach & Network Development

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Overview

Dr Matthews was recruited in 2007 to build and lead the section of interventional cardiology at USC. He has 35 years of experience in the catheter based treatment of a wide variety of cardiac disease states. He is well recognized as a pioneer in the performance of coronary interventions in patients too ill for bypass surgery, by using temporary ventricular assist devices during coronary stenting. Dr Mathews was one of the first cardiologists to close congenital heart defects percutaneously in Los Angeles and has since accumulated a large experience in ASD, VSD and PFO closure. Dr Matthews developed a structural heart program at USC over the past decade where he helped USC lead in the early development of TAVR procedures and now has performed well over 1000 of these procedures himself. Through his leadership, USC now has robust programs to percutaneously replace aortic, pulmonic and mitral valves as well.

Dr Matthews maintains a large practice of patients referred with cardiac abnormalities too challenging for community practitioners. He is also a dedicated teacher and scientist. He has trained over 80 interventional cardiologists who have gone on to successful practices all over the US and the world. He is a sought after speaker on the topic of structural heart disease and high risk coronary intervention. He is also involved in research projects to develop implantable sensors that are patient operated to detect heart failure at home and synthetically produced artificial TAVR valves. Dr Matthews continues to innovate and lead in interventional cardiology assisting in the development of numerous medical devices to facilitate the performance of cardiac procedures less invasively, safely and with excellent outcomes.

Awards

  • American Heart Association: Group Investigator Award, 1986
  • Harbor-UCLA Medical Center: Distinguished Teaching Award, 1987
  • American Heart Association: First Place, Clinical Division, Laverne Titus Young Investigator Competition, 1987
  • Division of Cardiovascular Medicine, Keck School of Medicine of USC: Golden Apple Award for Outstanding Teaching, 2013

Publications

  • Long-term outcomes of drug-eluting stents versus bare metal stents in saphenous vein graft interventions. Evidence from a meta-analysis of randomized controlled trials. Cardiovasc Revasc Med. 2018 12; 19(8):951-955.. View in PubMed
  • Incidence and treatment of severe primary mitral regurgitation in contemporary clinical practice. Cardiovasc Revasc Med. 2018 12; 19(8):960-963.. View in PubMed
  • Comparison of devices used in carotid artery stenting: A vascular quality initiative analysis of commonly used carotid stents and embolic protection devices. Catheter Cardiovasc Interv. 2018 10 01; 92(4):743-749.. View in PubMed
  • Comparison of Outcomes of Percutaneous Coronary Intervention on Native Coronary Arteries Versus on Saphenous Venous Aorta Coronary Conduits in Patients With Low Left Ventricular Ejection Fraction and Impella Device Implantation Achieved or Attempted (from the PROTECT II Randomized Trial and the cVAD Registry). Am J Cardiol. 2018 09 15; 122(6):966-972.. View in PubMed
  • Prevalence of high on-treatment (aspirin and clopidogrel) platelet reactivity in patients with critical limb ischemia. Cardiovasc Revasc Med. 2018 07; 19(5 Pt A):516-520.. View in PubMed
  • Switch to Ticagrelor in critical limb ischemia antiplatelet study (STT-CLIPS). Cardiovasc Revasc Med. 2018 Apr – May; 19(3 Pt B):319-323.. View in PubMed
  • Association of elevated triglycerides and acute myocardial infarction in young Hispanics. Cardiovasc Revasc Med. 2016 Dec; 17(8):510-514.. View in PubMed
  • Same-day discharge after coronary stenting and femoral artery device closure: A randomized study in stable and low-risk acute coronary syndrome patients. Cardiovasc Revasc Med. 2016 Apr-May; 17(3):155-61.. View in PubMed
  • Impact of Surgical Consultation on Outcomes in Hemodynamically Supported High-Risk Percutaneous Coronary Intervention: Insights From PROTECT II Randomized Study. J Invasive Cardiol. 2016 May; 28(5):187-92.. View in PubMed
  • The efficacy of objective and subjective predictors of driving performance during sleep restriction and circadian misalignment. Accid Anal Prev. 2017 Feb; 99(Pt B):445-451.. View in PubMed