Ray Matthews, MD

Professor of Clinical Medicine

Director of Interventional Cardiology and Catheterization Laboratories

Director, CVI Outreach & Network Development

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Overview

Dr Matthews was recruited in 2007 to build and lead the section of interventional cardiology at USC. He has 35 years of experience in the catheter based treatment of a wide variety of cardiac disease states. He is well recognized as a pioneer in the performance of coronary interventions in patients too ill for bypass surgery, by using temporary ventricular assist devices during coronary stenting. Dr Mathews was one of the first cardiologists to close congenital heart defects percutaneously in Los Angeles and has since accumulated a large experience in ASD, VSD and PFO closure. Dr Matthews developed a structural heart program at USC over the past decade where he helped USC lead in the early development of TAVR procedures and now has performed well over 1000 of these procedures himself. Through his leadership, USC now has robust programs to percutaneously replace aortic, pulmonic and mitral valves as well.

Dr Matthews maintains a large practice of patients referred with cardiac abnormalities too challenging for community practitioners. He is also a dedicated teacher and scientist. He has trained over 80 interventional cardiologists who have gone on to successful practices all over the US and the world. He is a sought after speaker on the topic of structural heart disease and high risk coronary intervention. He is also involved in research projects to develop implantable sensors that are patient operated to detect heart failure at home and synthetically produced artificial TAVR valves. Dr Matthews continues to innovate and lead in interventional cardiology assisting in the development of numerous medical devices to facilitate the performance of cardiac procedures less invasively, safely and with excellent outcomes.

Awards

  • American Heart Association: Group Investigator Award, 1986
  • Harbor-UCLA Medical Center: Distinguished Teaching Award, 1987
  • American Heart Association: First Place, Clinical Division, Laverne Titus Young Investigator Competition, 1987
  • Division of Cardiovascular Medicine, Keck School of Medicine of USC: Golden Apple Award for Outstanding Teaching, 2013

Publications

  • The Reply. Am J Med. 2015 Sep; 128(9):e35.. View in PubMed
  • Percutaneous left ventricular assist device for high-risk percutaneous coronary interventions: Real-world versus clinical trial experience. Am Heart J. 2015 Nov; 170(5):872-9.. View in PubMed
  • Early repolarization masquerading as STEMI. Am J Med. 2014 Nov; 127(11):e1-e2.. View in PubMed
  • Design and rationale of the ANALYZE ST study: a prospective, nonrandomized, multicenter ST monitoring study to detect acute coronary syndrome events in implantable cardioverter-defibrillator patients. Am Heart J. 2014 Oct; 168(4):424-429.e1.. View in PubMed
  • African-American patients are less likely to receive drug-eluting stents during percutaneous coronary intervention. Cardiovasc Revasc Med. 2014 Jun; 15(4):214-8.. View in PubMed
  • Utility of fluoroscopy in teaching trainees groin puncture technique. J Invasive Cardiol. 2014 Jan; 26(1):18-20.. View in PubMed
  • Predictors of reperfusion delay in patients with ST elevation myocardial infarction self-transported to the hospital (from the American Heart Association’s Mission: Lifeline Program). Am J Cardiol. 2014 Mar 01; 113(5):798-802.. View in PubMed
  • Catheter intervention in structural heart disease. Preface. Cardiol Clin. 2013 Aug; 31(3):ix-x.. View in PubMed
  • Transcatheter aortic valve replacement with CoreValve. Cardiol Clin. 2013 Aug; 31(3):351-61.. View in PubMed
  • Use of regadenoson for measurement of fractional flow reserve. Catheter Cardiovasc Interv. 2014 Feb 15; 83(3):369-74.. View in PubMed