Overview

Dr. Sun Young Lee is a board-certified retina surgeon and clinician-scientist at the University of Southern California, where she serves as a tenured Associate Professor of Ophthalmology and Physiology & Neuroscience. She has extensive expertise in diagnosing and managing complex, vision-threatening retinal conditions. Dr. Lee specializes in age-related macular degeneration, inherited retinal diseases, diabetic retinopathy, retinal detachment, and surgical complications. She is nationally and internationally recognized for her surgical precision, clinical expertise, and seamless dedication to patient care.

Dr. Lee’s patient care is empowered by cutting-edge research funded by the National Eye Institute. Her laboratory investigates the role of extracellular vesicles (EVs) in the pathogenesis and treatment of retinal disease. She leads the development of EV-based intraocular therapies, a transformative approach to targeted drug delivery, gene therapy, and regenerative medicine for blinding retinal disorders such as age-related macular degeneration, inherited retinal diseases, diabetic retinopathy. Her research is deeply committed to restoring and preserving vision in patients with challenging conditions and limited treatment options.

For more information on Dr. Lee’s work, visit LeeRetinaLab.com

Awards

  • ARVO Foundation: Eye Research/Retina Research Foundation Travel Grant, 2009
  • Los Angeles Ophthalmology Society (LASO): Dr. Henry & Lilian Nesburn Award for Best Research by a Resident, 2016
  • Women in Retina (WinR) Mentoring Program: Travel Grant, 2016
  • Fellowship Research Award: The Retina Society, 2017
  • Presbyterian Health Foundation (PHF): Clinician Scientist Development Award, 2019
  • Women in Retin (WinR)/ American Society of Retina Specialist (ASRS): Mina Chung Research Award, 2021
  • Alcon Research Institute: Young Investigator Award, 2023
  • American Society of Retina Specialists: Fellow, 2024
  • Association for Research in Vision and Ophthalmology (ARVO): Silver Fellow, 2025

Education and Training

  • Pusan National University, S. Korea — MD — 1999
  • University of Ulsan, S. Korea — PhD — 2007
  • Asan Medical Center , S. Korea — Ophthalmology Residency/Vitreoretinal Surgery Fellowship — 2007
  • Johns Hopkins University, MD — Post-doctoral Fellowship — 2010
  • University of Southern California, CA — Ophthalmology Residency — 2016
  • University of Iowa , IA — Vitreoretinal Surgery Fellowship — 2018

Research Funding

  • Extracellular vesicle-based intraocular therapy combined with active targeting of ocular neovascularization
    NIH/NEI · R01EY034193 · Feb 1, 2024 – Jan 31, 2029 · Role: Principal Investigator
  • Extracellular Vesicle Therapy for Diabetic Retinopathy
    NIH/NEI · R21EY035425 · Sep 30, 2023 – Aug 31, 2025 · Role: Principal Investigator
  • USC Alpha Clinic Network Expansion for Cell and Gene Therapies (PI: Buchanan, T)
    California Institute for Regenerative Medicine (CIRM) · Feb 1, 2023 – Jan 31, 2027 · Role: Vision Disorder Lead
  • Exosome based intraocular therapy combined with active targeting of ocular neovascularization
    NIH/NEI · R56EY034193 · Sep 30, 2022 – Sep 29, 2024 · Role: Principal Investigator
  • USC Roski Eye K12 Clinician-Vision Scientist Training Program
    NIH/NEI · K12EY028873 · Feb 1, 2022 – Jan 31, 2024 · Role: Scholar

Publications

  • The therapeutic effects of bevacizumab in patients with polypoidal choroidal vasculopathy. Korean J Ophthalmol. 2008 Jun; 22(2):92-9.. View in PubMed
  • Optical coherence tomography evaluation of detached macula from rhegmatogenous retinal detachment and central serous chorioretinopathy. Am J Ophthalmol. 2008 Jun; 145(6):1071-1076.. View in PubMed
  • Efficacy of intravitreal triamcinolone acetonide for eyes with postvitrectomy diabetic vitreous hemorrhage. Korean J Ophthalmol. 2007 Dec; 21(4):208-12.. View in PubMed
  • Retinal complications in patients with solid organ or bone marrow transplantations. Transplantation. 2007 Mar 27; 83(6):694-9.. View in PubMed
  • Clinical and OCT features in spontaneously progressive idiopathic choriovitreal neovascularization. Ophthalmic Surg Lasers Imaging. 2007 Mar-Apr; 38(2):151-3.. View in PubMed
  • Intravitreal triamcinolone acetonide in eyes with recurrent postvitrectomy diabetic vitreous hemorrhage. Am J Ophthalmol. 2006 Sep; 142(3):501-3.. View in PubMed
  • Mitomycin C, ceramide, and 5-fluorouracil inhibit corneal haze and apoptosis after PRK. Cornea. 2006 Jan; 25(1):55-60.. View in PubMed
  • Mitomycin C-induced reduction of keratocytes and fibroblasts after photorefractive keratectomy. Invest Ophthalmol Vis Sci. 2004 Sep; 45(9):2978-84.. View in PubMed
  • Pars plana vitrectomy for exuduative retinal detachment in coats-type retinitis pigmentosa. Retina. 2004 Jun; 24(3):450-2.. View in PubMed