Brian Applegate, PhD

Our research interests are broadly to develop novel biophotonic technologies for point-of-care diagnosis and monitoring of human disease as well as the basic scientific understanding of human disease.

• The Ohio State University, Columbus, OH — PhD — 12/2000 — Chemistry

• New technologies for imaging of the human cochlea
  NIH · R01DC023511 · Jul 1, 2026 – Apr 30, 2031 · Role: Principal Investigator
• New low cost technology for early detection of ear disorders
  NIH · R21DC023404 · Sep 17, 2025 – Aug 31, 2027 · Role: Principal Investigator
• Ultra-stable, phase sensitive, snapshot OCT system enabled by 2-Photon additive manufacturing
  NIH · R21GM149078 · Sep 15, 2023 – Aug 31, 2025 · Role: Principal Investigator
• High-Speed, Low-Cost, Image Remapping Spectral Domain Full-Field Optical Coherence Tomography for Retinal Imaging
  NIH · R21EY035108 · Jul 1, 2023 – Jun 30, 2025 · Role: Principal Investigator
• Comb Light Source/Imaging spectrometer for advanced Spectral Domain Optical Coherence Tomography
  NIH · R21GM135530 · Sep 1, 2020 – Aug 31, 2022 · Role: Principal Investigator
• Optical imaging technologies to identify residual cholesteatoma and improve ossiculoplasty outcomes
  NIH · R01EB027113 · Apr 1, 2019 – Dec 31, 2023 · Role: Principal Investigator
• Morphological and Molecular Imaging System for in vivo Atherosclerosis Research
  NIH · R01HL111361 · Apr 1, 2012 – Mar 31, 2019 · Role: Principal Investigator
• Development of high-resolution molecular imaging of endogenous chromophores with
  NIH · R21RR025799 · May 15, 2009 – Apr 30, 2013 · Role: Principal Investigator
• New Technologies for high resolution optical molecular imaging
  NIH · R21EB007729 · Jun 1, 2008 – May 31, 2011 · Role: Principal Investigator
• Bringing Molecular Contrast to OCT
  NIH · F32EB004237 · Sep 1, 2004 – Aug 31, 2006 · Role: Principal Investigator

• Oghalai, John
• Shera, Christopher
• Altoe, Alessandro
• Charaziak, Karolina
• Dewey, James
• Xu, Benjamin