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Cheng Ji, PhD

Professor of Research Medicine

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Phone +1 323 442 2224
Email [email protected]
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Overview

Dr. Ji joined the faculty of Keck School of Medicine of USC in September 2000. Prior to the faculty, he earned his M.S. in Chemistry from Shanghai Jiao Tong Univ. and completed his PhD in Biochemistry and postdoctoral fellowships in Pathology/Medicine at Univ. of California and Keck School of Medicine of USC, respectively. Dr. Ji’s research interests include cellular organelle (e.g., ER, Golgi, mitochondria, or lysosomes) stress and liver disease, alcohol-induced hyperhomocysteinemia, and hepatotoxicity of anti-viral drugs and substance use disorders. He was among the first discovered in vivo the association of ER stress response with development of liver disease. Dr. Ji has published original research papers in leading journals such as Gastroenterology, Journal of Hepatology, Hepatology, PNAS, Cell, Nature Nanotech. and Advanced Materials.

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Publications

  • New Insights into the Pathogenesis of Alcohol-Induced ER Stress and Liver Diseases. Int J Hepatol. 2014; 2014:513787.. View in PubMed
  • Glucose-regulated protein 78 may play a crucial role in promoting the pulmonary microvascular remodeling in a rat model of hepatopulmonary syndrome. Gene. 2014 Jul 15; 545(1):156-62.. View in PubMed
  • CD133 positive cells isolated from A549 cell line exhibited high liver metastatic potential. Neoplasma. 2014; 61(2):153-60.. View in PubMed
  • Expression of the 78 kD glucose-regulated protein is induced by endoplasmic reticulum stress in the development of hepatopulmonary syndrome. Gene. 2014 Mar 01; 537(1):115-9.. View in PubMed
  • Restoration of intrahepatic regulatory T cells through MMP-9/13-dependent activation of TGF-β is critical for immune homeostasis following acute liver injury. J Mol Cell Biol. 2013 Dec; 5(6):369-79.. View in PubMed
  • Altered methylation and expression of ER-associated degradation factors in long-term alcohol and constitutive ER stress-induced murine hepatic tumors. Front Genet. 2013; 4:224.. View in PubMed
  • Evaluation of protein extraction protocols for 2DE in marine ecotoxicoproteomics. Proteomics. 2013 Nov; 13(21):3205-10.. View in PubMed
  • Effects of Bacillus subtilis ANSB060 on growth performance, meat quality and aflatoxin residues in broilers fed moldy peanut meal naturally contaminated with aflatoxins. Food Chem Toxicol. 2013 Sep; 59:748-53.. View in PubMed
  • Detection of transgenic and endogenous plant DNA fragments and proteins in the digesta, blood, tissues, and eggs of laying hens fed with phytase transgenic corn. PLoS One. 2013; 8(4):e61138.. View in PubMed
  • Association of cyclin D and estrogen receptor α36 with hepatocellular adenomas of female mice under chronic endoplasmic reticulum stress. J Gastroenterol Hepatol. 2013 Mar; 28(3):576-83.. View in PubMed

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