Christopher Ching

Assistant Professor Of Research Neurology

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Overview

Dr. Ching is an Assistant Professor at The Imaging Genetics Center, part of the Mark and Mary Stevens Neuroimaging and Informatics Institute, where his research focuses on neuroimaging and genomic markers of psychiatric and neurodegenerative disorders. As a core organizing member of the Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium (ENIGMA), he designs and implements standardized processing and analysis techniques for large-scale, international neuroimaging studies for a wide range of brain conditions. He leads the ENIGMA Bipolar Disorder Working Group, an effort including >200 researchers from around the world pooling data and resources to improve our understanding of the biological processes driving bipolar disorder. In complementary work, he studies rare copy number variants like 22q11.2 Deletion Syndrome to understand how certain rare genetic mutations can lead to increased risk for developing psychiatric illness. Finally, he leads several large-scale transdiagnostic neuroimaging and genomic initiatives mapping the common and distinct brain and clinical factors across a range of serious mental illnesses.

Awards

  • USC: Postdoctoral Fellowship in Biomarkers in Alzheimer’s Disease NIAT32AG058507, 2019
     – 2021
  • UCLA: Neurobehavioral Genetics Predoctoral Fellowship, NIH/NIMH 5T32MH073526, 2015
     – 2016
  • UCLA: Neuroimaging Training Program, National Institutes of Health, R90 DA022768 and T90 DA023422, 2012
     – 2013
  • UCLA: National Science Foundation Alliance for Graduate Education and the Professoriate Grant, 2012
     – 2012

Education and Training

  • UCLA — PhD — Neuroscience
  • Pomona College — BA — Neuroscience/Philosophy

Research Keywords

  • Neuroscience
  • Neuoroimaging
  • Psychiatric Disorders
  • Genetics
  • Neurodegenerative Disease

Publications

  • Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years. Hum Brain Mapp. 2022 01; 43(1):452-469.. View in PubMed
  • Structural brain imaging studies offer clues about the effects of the shared genetic etiology among neuropsychiatric disorders. Mol Psychiatry. 2021 06; 26(6):2101-2110.. View in PubMed
  • Association of Immunosuppression and Viral Load With Subcortical Brain Volume in an International Sample of People Living With HIV. JAMA Netw Open. 2021 01 04; 4(1):e2031190.. View in PubMed
  • Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders. JAMA Psychiatry. 2021 Jan 01; 78(1):47-63.. View in PubMed
  • Brain structural correlates of insomnia severity in 1053 individuals with major depressive disorder: results from the ENIGMA MDD Working Group. Transl Psychiatry. 2020 12 08; 10(1):425.. View in PubMed
  • In vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics through Meta-Analysis Bipolar Disorder Working Group. Hum Brain Mapp. 2022 01; 43(1):385-398.. View in PubMed
  • Greater male than female variability in regional brain structure across the lifespan. Hum Brain Mapp. 2022 01; 43(1):470-499.. View in PubMed
  • Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder. Hum Brain Mapp. 2022 01; 43(1):414-430.. View in PubMed
  • What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group. Hum Brain Mapp. 2022 01; 43(1):56-82.. View in PubMed
  • Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group. Mol Psychiatry. 2021 09; 26(9):5124-5139.. View in PubMed