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Hyungjin Eoh, PhD

Associate Professor of Immunology and Immune Therapeutics and Ophthalmology

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Email [email protected]
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Awards

  • Donald E. & Delia B. Baxter Foundation: Junior Faculty Award, 2016
     – 2017
  • L.K Whittier Foundation: Whitter Health Sciences Initiative, 2017
     – 2018
  • Wright Foundation: Wright Foundation Research Awards, 2018
     – 2019
  • American Lung Association: Innovation Award, 2020
     – 2022
  • University of Southern California: KSOM Dean Fund, 2021
     – 2022

Research Funding

  • Interplay of M. tuberculosis trehalose metabolism and its pathogenesis and drug resistance
    NIH · R01AI168088 · Mar 16, 2023 – Feb 28, 2027 · Role: Principal Investigator
  • Characterizing CaeA-mediated rifampin tolerance in MTB
    NIH · R21AI167027 · Nov 10, 2022 – Oct 31, 2024 · Role: Co-Investigator
  • PknG mediated tailoring Mycobacterium tuberculosis adaptive metabolism is required for the persister formation
    NIH · R56AI143870 · Sep 10, 2019 – Aug 31, 2021 · Role: Principal Investigator
  • Metabolic compensation in Mycobacterium tuberculosis for the formation of persisters
    NIH · R21AI139386 · Mar 1, 2019 – Feb 28, 2021 · Role: Principal Investigator

Research Keywords

  • Metabolomics
  • Drug Discovery
  • Tuberculosis
  • Drug Resistance

Publications

  • Publisher Correction: Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. Nat Neurosci. 2022 Feb; 25(2):264.. View in PubMed
  • The Role of Fatty Acid Metabolism in Drug Tolerance of Mycobacterium tuberculosis. mBio. 2022 02 22; 13(1):e0355921.. View in PubMed
  • Arginine-mediated gut microbiome remodeling promotes host pulmonary immune defense against nontuberculous mycobacterial infection. Gut Microbes. 2022 Jan-Dec; 14(1):2073132.. View in PubMed
  • Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. Nat Neurosci. 2021 12; 24(12):1673-1685.. View in PubMed
  • Phosphoenolpyruvate depletion mediates both growth arrest and drug tolerance of Mycobacterium tuberculosis in hypoxia. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).. View in PubMed
  • Transcriptomic and Metabolomic Analysis Revealed Roles of Yck2 in Carbon Metabolism and Morphogenesis of Candida albicans. Front Cell Infect Microbiol. 2021; 11:636834.. View in PubMed
  • SP_0916 Is an Arginine Decarboxylase That Catalyzes the Synthesis of Agmatine, Which Is Critical for Capsule Biosynthesis in Streptococcus pneumoniae. Front Microbiol. 2020; 11:578533.. View in PubMed
  • A nutrient-limited screen unmasks rifabutin hyperactivity for extensively drug-resistant Acinetobacter baumannii. Nat Microbiol. 2020 09; 5(9):1134-1143.. View in PubMed
  • Oncogenic human herpesvirus hijacks proline metabolism for tumorigenesis. Proc Natl Acad Sci U S A. 2020 04 07; 117(14):8083-8093.. View in PubMed
  • Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis. Nat Commun. 2019 07 02; 10(1):2928.. View in PubMed

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