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Hyungjin Eoh, PhD

Associate Professor of Immunology and Immune Therapeutics and Ophthalmology

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Email [email protected]
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Awards

  • Donald E. & Delia B. Baxter Foundation: Junior Faculty Award, 2016
     – 2017
  • L.K Whittier Foundation: Whitter Health Sciences Initiative, 2017
     – 2018
  • Wright Foundation: Wright Foundation Research Awards, 2018
     – 2019
  • American Lung Association: Innovation Award, 2020
     – 2022
  • University of Southern California: KSOM Dean Fund, 2021
     – 2022

Research Funding

  • Interplay of M. tuberculosis trehalose metabolism and its pathogenesis and drug resistance
    NIH · R01AI168088 · Mar 16, 2023 – Feb 28, 2027 · Role: Principal Investigator
  • Characterizing CaeA-mediated rifampin tolerance in MTB
    NIH · R21AI167027 · Nov 10, 2022 – Oct 31, 2024 · Role: Co-Investigator
  • PknG mediated tailoring Mycobacterium tuberculosis adaptive metabolism is required for the persister formation
    NIH · R56AI143870 · Sep 10, 2019 – Aug 31, 2021 · Role: Principal Investigator
  • Metabolic compensation in Mycobacterium tuberculosis for the formation of persisters
    NIH · R21AI139386 · Mar 1, 2019 – Feb 28, 2021 · Role: Principal Investigator

Research Keywords

  • Metabolomics
  • Drug Discovery
  • Tuberculosis
  • Drug Resistance

Publications

  • Regulation of polar peptidoglycan biosynthesis by Wag31 phosphorylation in mycobacteria. BMC Microbiol. 2010 Dec 29; 10:327.. View in PubMed
  • Expression and validation of D-erythrulose 1-phosphate dehydrogenase from Brucella abortus: a diagnostic reagent for bovine brucellosis. J Vet Diagn Invest. 2010 Jul; 22(4):524-30.. View in PubMed
  • Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF. Chem Biol. 2010 Feb 26; 17(2):117-22.. View in PubMed
  • Expression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens. Chem Biol. 2009 Dec 24; 16(12):1230-9.. View in PubMed
  • The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target. Tuberculosis (Edinb). 2009 Jan; 89(1):1-11.. View in PubMed
  • Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase. Bioorg Med Chem Lett. 2008 Oct 01; 18(19):5320-3.. View in PubMed
  • Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol: A substrate for IspE. Tetrahedron Lett. 2008 Jul 21; 49(29-30):4461-4463.. View in PubMed
  • Characterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug development. J Bacteriol. 2007 Dec; 189(24):8922-7.. View in PubMed
  • Antigens secreted from Mycobacterium tuberculosis: identification by proteomics approach and test for diagnostic marker. Proteomics. 2004 Nov; 4(11):3299-307.. View in PubMed

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