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Hyungjin Eoh, PhD

Associate Professor of Immunology and Immune Therapeutics and Ophthalmology

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Email [email protected]
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Awards

  • Donald E. & Delia B. Baxter Foundation: Junior Faculty Award, 2016
     – 2017
  • L.K Whittier Foundation: Whitter Health Sciences Initiative, 2017
     – 2018
  • Wright Foundation: Wright Foundation Research Awards, 2018
     – 2019
  • American Lung Association: Innovation Award, 2020
     – 2022
  • University of Southern California: KSOM Dean Fund, 2021
     – 2022

Research Funding

  • Interplay of M. tuberculosis trehalose metabolism and its pathogenesis and drug resistance
    NIH · R01AI168088 · Mar 16, 2023 – Feb 28, 2027 · Role: Principal Investigator
  • Characterizing CaeA-mediated rifampin tolerance in MTB
    NIH · R21AI167027 · Nov 10, 2022 – Oct 31, 2024 · Role: Co-Investigator
  • PknG mediated tailoring Mycobacterium tuberculosis adaptive metabolism is required for the persister formation
    NIH · R56AI143870 · Sep 10, 2019 – Aug 31, 2021 · Role: Principal Investigator
  • Metabolic compensation in Mycobacterium tuberculosis for the formation of persisters
    NIH · R21AI139386 · Mar 1, 2019 – Feb 28, 2021 · Role: Principal Investigator

Research Keywords

  • Metabolomics
  • Drug Discovery
  • Tuberculosis
  • Drug Resistance

Publications

  • Inhibiting the stringent response blocks Mycobacterium tuberculosis entry into quiescence and reduces persistence. Sci Adv. 2019 03; 5(3):eaav2104.. View in PubMed
  • Bacterial Protein Reshapes Host Defense toward Antiviral Responses. Mol Cell. 2018 08 16; 71(4):483-484.. View in PubMed
  • Glutamate mediated metabolic neutralization mitigates propionate toxicity in intracellular Mycobacterium tuberculosis. Sci Rep. 2018 05 31; 8(1):8506.. View in PubMed
  • Endothelial lineage-specific interaction of Mycobacterium tuberculosis with the blood and lymphatic systems. Tuberculosis (Edinb). 2018 07; 111:1-7.. View in PubMed
  • TRIM56-mediated monoubiquitination of cGAS for cytosolic DNA sensing. Nat Commun. 2018 02 09; 9(1):613.. View in PubMed
  • A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus. mBio. 2017 08 15; 8(4).. View in PubMed
  • Δ20 IFITM2 differentially restricts X4 and R5 HIV-1. Proc Natl Acad Sci U S A. 2017 07 03; 114(27):7112-7117.. View in PubMed
  • Metabolic anticipation in Mycobacterium tuberculosis. Nat Microbiol. 2017 May 22; 2:17084.. View in PubMed
  • Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2017 03 14; 114(11):E2225-E2232.. View in PubMed
  • Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis. ACS Infect Dis. 2016 12 09; 2(12):958-968.. View in PubMed

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