Mark S. Borchert, MD

Clinical Professor of Ophthalmology (Part-Time)

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Overview

Mark S. Borchert, MD earned a medical degree from Baylor College of Medicine. He completed his residency in the Department of Ophthalmology, University of Southern California, and a fellowship in neuro-ophthalmology at the Massachusetts Eye & Ear Infirmary, Harvard University. Dr. Borchert is the Director of Eye Birth Defects, leading the world’s largest study into optic nerve hypoplasia. Dr. Borchert, who has been listed in “Best Doctors in America,” also has received honors from the Pan American Association of Ophthalmology, the American Academy of Ophthalmology, and Society of Heed Fellows, as well as several teaching awards from the Keck School of Medicine. His research on the development of the retina and optic nerve in rats was part of an experiment on the NASA space shuttle.

Borchert investigates the development of the optic nerve and its retinotopic connections in the tectum (part of the midbrain) and thalamus (part of the forebrain). He is interested in the role that inaccurate or inadequate development of these connections plays in the pathogenesis of optic nerve hypoplasia, the leading cause of blindness in infants in the United states and Europe. His research focus also includes developing diagnostic tools using spectroscopic methods in the measurement of glucose levels in the eye.

Awards

  • Keck School of Medicine of USC: Resident Teaching Award, 1991
     – 1994
  • Keck School of Medicine of USC: Senior Resident Teaching Award, 1994
  • Keck School of Medicine of USC: Resident Teaching Award, 1996
  • Keck School of Medicine of USC: Resident Teaching Award, 1999
  • Keck School of Medicine of USC: Resident Teaching Award, 2001
  • American Academy of Ophthalmology: Achievement Award, 2002
  • America’s Top Doctors, 2006
     – 2009
  • Best Doctors in America Award, 2006
  • Pasadena Magazine Top Doctors Award, 2008
  • LA Magazine Best Doctors in Southern California, 2009
  • Best Doctors in America Award, 2009
  • LA Magazine: Super Doctors Award, 2010
  • Pasadena Magazine Top Doctors Award, 2010
  • Pasadena Magazine Top Doctors Award, 2013
     – 2014

Education and Training

  • Baylor College of Medicine — MD — 1983
  • USC Roski Eye Institute — Ophthalmology Residency — 1987
  • Massachusetts Eye & Ear Infirmary — Neuro-Ophthalmology Fellowship — 1988

Publications

  • The Nictavi Tarsus Patch: A New Device for Achieving Temporary Eyelid Closure in Lagophthalmos. Clin Ophthalmol. 2023; 17:1877-1884.. View in PubMed
  • Association of prepregnancy body mass index and gestational weight gain on severity of optic nerve hypoplasia. Birth Defects Res. 2023 04 15; 115(7):753-763.. View in PubMed
  • Full-field Scotopic Threshold Improvement after Voretigene Neparvovec-rzyl Treatment Correlates with Chorioretinal Atrophy. Ophthalmology. 2023 07; 130(7):764-770.. View in PubMed
  • Subretinal deposits in young patients treated with voretigene neparvovec-rzyl for RPE65-mediated retinal dystrophy. Br J Ophthalmol. 2023 03; 107(3):299-301.. View in PubMed
  • The Pediatric Optic Neuritis Prospective Outcomes Study: Two-Year Results. Ophthalmology. 2022 08; 129(8):856-864.. View in PubMed
  • Neovascularization of the optic disc and peripheral retinal ischemia in a child with a novel variant in ALMS1 (Alström syndrome). Am J Ophthalmol Case Rep. 2022 Jun; 26:101506.. View in PubMed
  • Characteristics and Outcomes of Idiopathic and Non-idiopathic Ocular Motor Apraxia in Children. J Pediatr Ophthalmol Strabismus. 2022 Sep-Oct; 59(5):326-331.. View in PubMed
  • Delayed Diagnosis of Childhood-Onset Huntington Disease in an 8-Year-Old Boy With Ocular Motor Apraxia. J Neuroophthalmol. 2023 12 01; 43(4):e304-e305.. View in PubMed
  • Increase in Pediatric Pseudotumor Cerebri Syndrome Emergency Department Visits, Inpatient Admissions, and Surgeries During the COVID-19 Pandemic. J Neuroophthalmol. 2022 03 01; 42(1):e87-e92.. View in PubMed
  • Paroxysmal tonic upgaze (PTU) associated with CACNA1A mutation and gross motor delay. J AAPOS. 2021 12; 25(6):353-353.e1.. View in PubMed