Dynamic Research for
Alzheimer’s Prevention

At the USC Center for Personalized Brain Health, we believe that the best way to fight Alzheimer’s disease is to stop injury to the brain before it starts. Our interdisciplinary research keys on a gene carried by over half of Alzheimer’s patients. By translating science into clinical impact, we aim to bring personalized prevention to people facing high risk.

Personalized Brain Health Research

Biomarker Discovery

We’re uncovering biological markers for Alzheimer’s disease and building a pipeline of potential treatments that address inflammation in the brain. First in line is a new drug that has shown promise in lab studies.

Imaging Innovations

Imaging techniques under development at the Center for Personalized Brain Health may profile Alzheimer’s risk and inform interventions. We’re looking for early brain changes, well before damage starts — and decades before symptoms appear.

Digital Tools for Early Detection

USC biomedical researchers and engineers collaborate to develop and deploy advanced technology for early detection. Measuring lapses in the brain’s internal GPS could enable people to get help before Alzheimer’s memory loss sets in.

From the Director

Most people with APOE4 don’t get neurological attention until they have dementia. Our center is going to provide resources to these individuals well before they get the disease.

Professor Hussein Yassine, MD
Professor Hussein Yassine, MD

Get Involved

You can make a difference in the fight against Alzheimer’s disease. Your gift helps turn bold ideas and groundbreaking findings into new Alzheimer’s prevention and treatment strategies. You can also become a partner in our work — with the potential benefit of personalized care.